anisakiasis is easily diagnosed when a nematode is extracted from
a patient, either by coughing or by the crawling of the larvae from
the patient's anus. This diagnosis is confirmed if the patient has
a history of eating raw fish.
of acute gastric anisakiasis is obtained by endoscopy and the removal
of the larvae with forceps.
test (RAST) has been in recent development, and tests for IgE and
IgG antibodies in the serum of potential patients, using antigens
prepared from larval stage Anisakis simplex. If the serum is
RAST-positive for the A. simplex antigen, then the diagnosis
is confirmed. However, a potential drawback to such a serologic test
is its nonspecificity due to cross-reactions between various helminths.
Section of Anisakis in the ileum
of a Japanese patient.
Link to Case
Study #4 and #5