Since human dirofilariasis infection is rare and generally occurs in isolated cases, the epidemiology of human dirofilariasis is not well understood.  However, several factors are known to influence the frequency and distribution of infection, including: 1-the size of the natural host population in a particular area, 2-the prevalence of infection in the natural host population, 3-the density of the vector population (mosquitoes of various species), and 4-the degree of human exposure to the bite of infected mosquitoes (Villanueva, Rodriguez-Perez).

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