Treatment and Management



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The optimal treatment for Oesophagostomiasis is controversial. Although removal of nodules by sectional colectomy is recommended, treatment with different parasitic drugs offers promising alternatives. Treatment with drugs such as albendazole, pyrantel pamoate, levamisole, and thiabendazole might play a critical role in treating people who are infected and had colon nodules but are asymptomatic. If left untreated, people with asymptomatic nodular disease will go on to develop the pathological form of the disease.



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Storey et al. (2000) investigated the effects of high dose Albendazole treatments administered to infected, asymptomatic children in Ghana. The treatment was found to reduce the number and size of the nodules as detected by ultrasound and also decreased to rates of Oesophagostomiasis disease development. Albendazole did not affect the number of new cases the following year though. It is hypothesized that albendazole may be a useful therapy for asymptomatic infections.

In addition to albendazole, other anti-parasitic drugs have been tested for their ability to treat Oesophagostomiasis. Krepel et al.(2000) found that although albendazole was best at decreasing the disease burden in patients, 2x10 mg/kg of pyrantel pamoate was also effective. The cure rates for thiabendazole were moderate and poor for levamisole. The availability of a variety of drugs to treat this disease effectively needs to be further developed.


Introduction
Classification
Life Cycle
Epidemiology
Clinical Manifestations
Diagnosis
Treatment
Links
References
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