- The optimal treatment for Oesophagostomiasis
controversial. Although removal of nodules by sectional colectomy is
recommended, treatment with different parasitic drugs offers promising
alternatives. Treatment with drugs such as albendazole, pyrantel pamoate,
levamisole, and thiabendazole might play a critical role in treating
people who are infected and had colon nodules but are asymptomatic. If
left untreated, people with asymptomatic nodular disease will go on to
develop the pathological form of the disease.
Storey et al. (2000) investigated the effects of high dose
Albendazole treatments administered to infected, asymptomatic children in
Ghana. The treatment was found to reduce the number and size of the
nodules as detected by ultrasound and also decreased to rates of
Oesophagostomiasis disease development. Albendazole did not affect the
number of new cases the following year though. It is hypothesized that
albendazole may be a useful therapy for asymptomatic infections.
Borrowed from http://pages.tias.com/18/PictPage/995742.html
In addition to albendazole, other anti-parasitic drugs have been tested
for their ability to treat Oesophagostomiasis. Krepel et al.(2000) found
that although albendazole was best at decreasing the disease burden in
patients, 2x10 mg/kg of pyrantel pamoate was also effective. The cure
rates for thiabendazole were moderate and poor for levamisole.
The availability of a variety of drugs to treat this disease effectively
needs to be further developed.
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