HISTORY OF DISEASE:
- 1550BC - Hookworm
described in Egyptian Papyrus Ebers.
- The ancient Chinese,
Hippocrates, and Lucretius all describe symptoms of the condition
- N. americanus
was probably introduced from Africa with the slave trade.
- 1843 - Milan physician
Angelo Dubini discovers A. duodenale.
- 1878 - In Europe,
Grassi shows that hookworm infection can be diagnosed microscopically
by searching for eggs in a stool sample.
- 1880 - Anemia
outbreak during construction of St. Gotthard tunnel between Italy and
Switzerland. Attributed to hookworm. Later spread by workers to mines
- 1888 - Lutz discovers
N. americanus species in Brazil.
- 1902- C.A. Bentley
makes connection between ground itch and A. duodenale
- 1904 - German
helminthologist Arthur Loos elucidates hookworm transmission while in
- 1909 - Rockefeller
donates $1 million to found the Rockefeller
Sanitary Commission for the Eradication of Hookworm Disease.
- 2000 - Bill
& Melinda Gates Foundation gives $18 million to the Albert
B. Sabin Vaccine Institute to develop a genetically engineered hookworm