The above image shows the adult M. yokogawai in the small intestine, between the intestinal villi. While attached to the intestinal wall, the adult worms usually produce no symptoms, unless they are present in large numbers.

The clinical manifestations of metagonimiasis include:

Occasionally, the worms may burrow into and invade the intestinal mucosa, which can ellicit an inflammatory immune response by the host. These worms can then deposit eggs in the tissues, which may subsequently enter the host's circulation. If this happens, the eggs can migrate to extra-intestinal sites, such as the brain, spinal cord, or heart. Ulceration can occur, and granulomas can form around the eggs. These granulomas can lead to severe consequences, including:

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