Fetal Radiation Dose Estimates

 

 
FETAL RADIATION DOSES CONSEQUENTIAL TO SELECTED NUCLEAR MEDICINE PROCEDURES

The radiation doses to the fetus at various points in gestation for a number of diagnostic nuclear medicine studies are tabulated below. "Early" refers to irradiation during the first portion of the first trimester; "Months 3, 6 and 9" to irradiation at the ends of the first, second and third trimesters respectively. The doses are expressed in millirads, and assume an amount of administered radioactivity which is customary for the study. When an agent has several indications using different administered activities, the highest value is assumed.

Studies for which values appear in yellow cells can carry an increased risk. Please refer to the "Risks" page for more information.

The information supplied for I-131 sodium iodide and I-131 MIBG is for diagnostic studies. Therapeutic procedures with these radiopharmaceuticals incur far higher doses and require special computational treatment.

Radiopharmaceutical

Early

Month 3
Month 6
Month 9

Co-57 Vitamin B-1, Normal-Flushing

4

3

3

4

Co-57 Vitamin B-12, Normal-No Flushing

6

4

5

5

Co-57 Vitamin B-12, PA- Flushing

1

1

1

1

Co-57 Vitamin B-12, PA- No Flushing

1

1

1

1

Co-58 Vitamin B-12, Normal-Flushing

8

6

6

6

Co-58 Vitamin B-12, Normal-No Flushing

11

8

9

9

Co-58 Vitamin B-12, PA-Flushing

2

2

2

1

Co-58 Vitamin B-12, PA-No Flushing

3

3

2

2

F-18 FDG

999

629

348

300

Ga-67 Citrate

1,767

3,800

3,420

2,470

I-123 Hippuran

233

180

63

59

I-123 IMP

380

220

142

118

I-123 MIBG

630

420

238

217

I-123 Sodium Iodide

60

42

33

29

I-125 HSA

50

16

8

5

I-125 Sodium Iodide

2

1

< 1

< 1

I-131 HSA

26

9

8

7

I-131 MAA

369

231

220

231

I-131 MIBG

220

108

76

70

I-131 Rose Bengal

1

1

1

<1

I-131 Sodium Iodide

288

272

920

1,080

In-111 DTPA

130

96

40

36

In-111 Pentetreotide

1,886

1,380

805

713

In-111 Platelets

170

110

99

89

In-111 White Blood Cells

260

192

192

188

Tc-99m Disofenin

595

525

420

235

Tc-99m DMSA

112

103

88

75

Tc-99m DTPA

900

653

308

353

Tc-99m DTPA Aerosol

23

17

9

12

Tc-99m Glucoheptonate

900

825

398

345

Tc-99m HDP

390

405

225

188

Tc-99m HMPAO

653

503

360

270

Tc-99m Human Serum Albumin

102

60

52

44

Tc-99m MAA

62

88

110

88

Tc-99m MAG3

1,350

1,050

413

390

Tc-99m MDP

458

405

203

180

Tc-99m MIBI-rest

1,650

1,320

924

594

Tc-99m MIBI-stress

1,320

1,045

759

484

Tc-99m Pertechnetate

1,210

2,420

1,540

1,023

Tc-99m PYP

420

462

252

203

Tc-99m RBC-in vitro

632

437

316

260

Tc-99m RBC-in vivo

595

400

307

251

Tc-99m Sulfur Colloid-Liver Disease

144

113

126

126

Tc-99m Sulfur Colloid-normal

81

95

144

167

Tc-99m White Blood Cells

76

56

58

56

Tl-201 Chloride

1,455

870

705

405

Xe-133, 5 minute rebreathing, 10 liter spirometer volume

19

2

2

1

Xe-133, 5 minute rebreathing, 5 liter spirometer volume

31

4

3

2

Xe-133, 5 minute rebreathing, 7.5 liter spirometer volume

17

2

1

1

Xe-133, injection

1

< 1

< 1

< 1

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