Daniel Herschlag

Professor of Biochemistry

Research areas:



The overarching goal of the Herschlag Lab is to understand the fundamental behavior of RNA and proteins and, in turn, how these behaviors determine and impact biological catalysis and biology. The lab takes an interdisciplinary approach, spanning and integrating physics, chemistry and biology, and a wide range of techniques are employed. We study the underlying mechanisms responsible for the enormous catalytic power and exquisite specificity of enzymes, both protein and RNA, the folding landscape of structured RNA molecules, and the genomic and cellular properties of RNA molecules and their regulation and coordination. I direct “Biological Macromolecules” (Structural Biology 241), which is a uniquely organized course aimed at conveying the essential principles of the properties and fundamental features of biological macromolecules.

Courses Taught