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Jan M. Skotheim

Assistant Professor of Biology and, by courtesy, of Chemical and Systems Biology

Research areas:

Description

Biophysics

Our laboratory works on general aspect of control as applied to the cell division cycle. In spite of our exquisite molecular knowledge, we lack a precise understanding of the regulatory dynamics associated with cell cycle transitions. Surprisingly, although size control has been known about since the 1970’s, we still do not know the mechanisms that allow a cell to compute its own size. Through studies with yeast and higher eukaryotes, we aim to lay the groundwork for a more satisfying systems-level understanding of the cell cycle and size control. I teach a graduate level course on the principles of cell cycle control (Bio171/271 Csb271) which aims to apply basic concepts from nonlinear dynamics to the study of the regulatory genetic networks controlling cell division. This interdisciplinary course attracts students from a wide range of backgrounds.

Courses Taught