STANFORD BRAIN TUMOR CENTER
The Stanford Brain Tumor Center combines multidisciplinary clinical care
and a strong research program in an effort to facilitate rapid transfer
of basic scientific findings into clinical protocols for patients with
tumors of the brain, skull base and spine. The Center has innovative clinical
initiatives organized under the auspices of the Stanford
Neuro-Oncology Program; the Stanford Pediatric Brain Tumor Program,
the Stanford Skull Base Surgery Program, the Stanford Tumor Radiosurgery
Program, the Stanford Spinal Tumor Program and the Stanford Neuro-Endocrinology
Diseases treated in the Center include both benign and malignant tumors
of the brain, spinal cord, skull base, and spine in adults and children.
Targeted pathologies include primary parenchymal tumors (including gliomas,
craniopharyngiomas, germ cell tumors, and lymphomas), metastatic tumors
(including parenchymal, leptomenngeal, and osseous lesions) and tumors
of the skull base (including meningiomas, osseous and cartilagenous tumors,
pituitary adenomas, acoustic neuromas and glomus tumors).
Minimally invasive therapies, such as radiosurgery, are a particular strength.
Studies of innovative treatment currently underway include the following:
- Fractionated radiosurgery for acoustic neuromas
- Timozodamide for adult malignat gliomas
- Oxygenation agents as radiosensitizers
- Combination chemotherapy for pediatric tumors
Brain tumors, or neurological complications of other cancers, often
have profound implications for patients and their families. Caring for
patients with neuro-oncological disease is a complex task that requires
input from many specialists.
To meet these challenges, the Stanford
Neuro-Oncology Program has developed an interdisciplinary team whose
goals are the following:
- To provide a specific and accurate diagnosis
- To communicate to the patient and the patient's family the nature,
treatment options, and possible outcomes of the disease
- To offer both conventional and experimental treatments
- To optimize the quality of each patient's life
- To assist the patient and the patient's family in coping with the
The Department maintains an active pediatric tumor practice at the Lucille
Salter Packard Children's Hospital. Here, advanced multimodality therapy
for a wide varienty of brain
tumors in children is offered in a collaborative multidisciplinary
Pediatric Neuro-Oncology Clinic.
Basic science research efforts within the Department include investigation
of the following:
- The regulatory mechanism of tumor angiogenesis
- Tumor angiogenesis as a target for gene therapy
- Gene therapy involving insertion of tumor suppressor genes
- Tumor cell invasion and establishment of therapeutic neuronal grafts
- The utility of bio-chips and cybo-technology in degenerative diseases.
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