Bryant Molecular Motors Lab

Lebel P, Basu A, Oberstrass FC, Tretter EM, and Bryant Z, "Gold rotor bead tracking for high-speed measurements of DNA twist, torque, and extension." Nat Methods 2014
Pubmed | Nature Methods | PDF | Supplementary

Schindler TD, Chen L, Lebel P, Nakamura M, Bryant Z "Engineering myosins for long-range transport on actin filaments." Nat Nanotechnol 2014
Pubmed | PDF | Editorial | News and Views

Cipriano DJ, Jung J, Vivona S, Fenn TD, Brunger AT, Bryant Z "Processive ATP-driven substrate disassembly by the N-ethylmaleimide-sensitive factor (NSF) molecular machine." J Biol Chem 2013 Pubmed | PDF

Oberstrass FC, Fernandes LE, Lebel P, and Bryant Z "Torque Spectroscopy of DNA: Base-Pair Stability, Boundary Effects, Backbending, and Breathing Dynamics." Phys Rev Lett 2013 PDF | Physics Highlight

Bryant Z, Oberstrass FC, and Basu A "Recent developments in single-molecule DNA mechanics." Curr Opin Struct Biol 2012 Pubmed | PDF

Basu A, Schoeffler AJ, Berger JM, and Bryant Z "ATP controls distinct structural transitions of E. Coli DNA gyrase in complex with DNA." Nat Struct Mol Biol 2012 Pubmed | PDF | Cover

Oberstrass FC, Fernandes LE, and Bryant Z "Torque measurements reveal sequence-specific structural transitions in supercoiled DNA." Proc Natl Acad Sci USA 2012 Pubmed | PDF

Chen L, Nakamura M, Schindler TD, Parker D, and Bryant Z "Engineering controllable bidirectional molecular motors based on myosin." Nat Nanotechnol 2012 Pubmed | PDF | News and Views

Elting MW, Bryant Z, Liao J-C, and Spudich JA "Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI." Biophys J 2011 Pubmed | PDF

Dunn AR, Chuan P, Bryant Z, and Spudich JA "Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing." Proc Natl Acad Sci USA 2010 Pubmed | PDF

Parker D, Bryant Z, and Delp S. "Coarse-grained structural modeling of molecular motors using multibody dynamics." Cellular and Molecular Bioengineering 2009 Pubmed | PDF

Liao JC, Elting MW, Spudich JA, and Bryant Z "Engineered myosin VI motors reveal minimal structural determinants of directionality and processivity." J Mol Biol 2009 Pubmed | PDF

Nöllmann M, Stone MD, Bryant Z, Gore J, Crisona NJ, Hong SC, Mitelheiser S, Maxwell A, Bustamante C, and Cozzarelli NR "Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque." Nat Struct Mol Biol 2007;14: 4: 264-71 Pubmed | PDF

Bryant Z, Altman D, and Spudich JA "The power stroke of myosin VI and the basis of reverse directionality." Proc Natl Acad Sci U S A 2007; 104: 3: 772-7 Pubmed | PDF

Gore J, Bryant Z, Nöllmann M, Le MU, Cozzarelli NR, and Bustamante C "DNA overwinds when stretched." Nature 2006; 442: 7104: 836-9 Pubmed | PDF

Gore J, Bryant Z, Stone MD, Nöllmann M, Cozzarelli NR, and Bustamante C "Mechanochemical analysis of DNA gyrase using rotor bead tracking." Nature 2006; 439: 7072: 100-4 Pubmed | PDF

Bryant Z, Stone MD, Gore J, Smith SB, Cozzarelli NR, and Bustamante C "Structural transitions and elasticity from torque measurements on DNA." Nature 2003; 424: 6946: 338-41 Pubmed | PDF

Stone MD, Bryant Z, Crisona NJ, Smith SB, Vologodskii A, Bustamante C, and Cozzarelli NR "Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases." Proc Natl Acad Sci U S A 2003; 100: 15: 8654-9 Pubmed | PDF

Bustamante C, Bryant Z, and Smith SB "Ten years of tension: single-molecule DNA mechanics." Nature 2003; 421: 6921: 423-7 Pubmed | PDF

Bryant Z, Pande VS, and Rokhsar DS "Mechanical unfolding of a beta-hairpin using molecular dynamics." Biophys J 2000; 78: 2: 584-9 Pubmed | PDF

Bryant Z, Subrahmanyan L, Tworoger M, LaTray L, Liu CR, Li MJ, van den Engh G, and Ruohola-Baker H "Characterization of differentially expressed genes in purified Drosophila follicle cells: toward a general strategy for cell type-specific developmental analysis." Proc Natl Acad Sci U S A 1999; 96: 10: 5559-64 Pubmed | PDF

Tworoger M, Larkin MK, Bryant Z, and Ruohola-Baker H "Mosaic analysis in the drosophila ovary reveals a common hedgehog-inducible precursor stage for stalk and polar cells." Genetics 1999; 151: 2: 739-48 Pubmed | PDF

Clegg NJ, Frost DM, Larkin MK, Subrahmanyan L, Bryant Z, and Ruohola-Baker H "maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA." Development 1997; 124: 22: 4661-71 Pubmed | PDF

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