(3) Materials chemistry approaches to nano-biotechnology and nano-medicine
Overall, our research in this area is aimed at:
- - Utilization of the unique physical properties of nanomaterials for biological systems.
- - Development of better detection, imaging, diagnosis and treatment of diseases (cancer, atherosclerosis...) using based on interesting properties of nanomaterials.
Our research in this area includes the following aspects:
- Synthesis and functionalization of novel nanomaterials for biological applications
- - Carbon nanotubes, nano-graphene oxide, FeCo/graphene nanocrystals, plasmonic Au/Au films, plasmonic Au nanoplates
- Biosensors and microarrays
- - Multiplexed, multicolor Raman tags for protein microarrays with SERS; Fluorescence based microarrays on Au/Au nanofilms with metal enhanced photoluminescence.
- - Development of microarrays with broad dynamic range and high sensitivity.
- Near-infrared fluorescence enhanced molecular imaging and single cell tracking on plasmonic Au substrates
- - Up to 10 fold fluorescence enhancement of NIR fluorophores (dyes, nanotubes, quantum dots) for highly sensitive molecular imaging.
- Near infrared imaging (0.8-1.4 mm) in vivo
- - Imaging beyond the traditional NIR 0.7-0.9 mm window from cells to animals.
- Materials for drug delivery (small molecules, siRNA…), photothermal therapy and synergistic combination for cancer treatment
- - Nanomaterials for disease treatment with high efficacy, low toxic side effects at low doses.