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  78. Kempadoo KA, Tourino C, Cho SL, Magnani F, Leinninger G-M, Stuber GD, Zhang F, Myers MG, Deisseroth K, de Lecea L, Bonci, A. Hypothalamic Neurotensin Projections Promote Reward by Enhancing Glutamate Transmission in the VTA. J Neuroscience. May 1, 2013. 33(18):7618-26. [ PDF ]
  79. Stroh A, Adelsberger H, Groh A, Ruhlmann C, Fischer S, Schierloh A, Deisseroth K, Konnerth A. Making Waves: Initiation and Propagation of Corticothalamic Ca2+ Waves In Vivo. Neuron. March 20, 2013. 77:1136-50 [ PDF ]
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  81. Kim SY, Adhikari A, Lee SY, Marshel JH, Kim CK, Mallory CS, Lo M, Pak S, Mattis J, Lim BK, Malenka RC, Warden MR, Neve R, Tye KM, Deisseroth K. Diverging neural pathways assemble a behavioural state from separable features in anxiety. Nature. Advance Online Publication 2013 Mar 20. [ PDF | Supplementary Information | News & Views ]
  82. Zalocusky K, Deisseroth K. Optogenetics in the behaving rat: integration of diverse new technologies in a vital animal model. Optogenetics. Mar. 2013 [ PDF ]
  83. Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, Kim SY, Adhikari A, Thompson KR, Andalman AS, Gunaydin LA, Witten IB, Deisseroth K. Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature. Advance Online Publication 2012 Dec. [ PDF | Supplementary Information ]
  84. Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, Lobo MK, Neve RL, Friedman JM, Russo SJ, Deisseroth K, Nestler EJ, Han MH. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. Advance Online Publication 2012 Dec. [ PDF | Supplementary Information ]
  85. Warden MR, Selimbeyoglu A, Mirzabekov JJ, Lo M, Thompson KR, Kim SY, Adhikari A, The KM, Frank LM, Deisseroth K. A prefrontal cortex-brainstem neuronal projection that controls response to behavioural challenge. Nature. 2012 Dec 20;492(7429):428-32. [ PDF | Supplementary Information ]
  86. Paz JT, Davidson TJ, Frechette ES, Delord B, Parada I, Peng K, Deisseroth K, Huguenard JR. Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury. Nat Neurosci. 2013 Jan;16(1):64-70. Epub 2012 Nov 7. [ PDF ]
  87. Prakash R, Yizhar O, Grewe B, Ramakrishnan C, Wang N, Goshen I, Packer AM, Peterka DS, Yuste R, Schnitzer MJ, Deisseroth K. Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation. Nat Methods. Advance Online Publication 2012 Nov 11. [ PDF | Supplemental Information ]
  88. Packer AM, Peterka DS, Hirtz JJ, Prakash R, Deisseroth K, Yuste R. Two-photon optogenetics of dendritic spines and neural circuits. Nat Methods. 2012 Dec 7;9(12):1202-5. Epub 2012 Nov 11. [ PDF | Supplemental Information ]
  89. Deisseroth K. Optogenetics and psychiatry: applications, challenges, and opportunities. Biol Psychiatry. 2012 Jun 15;71(12):1030-2. Epub 2012 Apr 13. [ PDF ]
  90. Ferenczi E, Deisseroth K. When the electricity (and the lights) go out: transient changes in excitability. Nat Neurosci. 2012 Jul 26;15(8):1058-60. [ PDF ]
  91. Tanaka KF, Matsui K, Sasaki T, Sano H, Sugio S, Fan K, Hen R, Nakai J, Yanagawa Y, Hasuwa H, Okabe M, Deisseroth K, Ikenaka K, Yamanaka A. Expanding the Repertoire of Optogenetically Targeted Cells with an Enhanced Gene Expression System. Cell Rep. 2012 Aug 30;2(2):397-406. Epub 2012 Jul 26. [ PDF with Supplemental Information ]
  92. Liu X, Ramirez S, Pang PT, Puryear CB, Govindarajan A, Deisseroth K, Tonegawa S. Optogenetic stimulation of a hippocampal engram activates fear memory recall. Nature. 2012 Mar 22;484(7394):381-5. [ PDF | Supplemental Information ]
  93. Tye KM, Deisseroth K. Optogenetic investigation of neural circuits underlying brain disease in animal models. Nat Rev Neurosci. 2012 Mar 20;13(4):251-66. [ PDF ]
  94. Gee S, Ellwood I, Patel T, Luongo F, Deisseroth K, Sohal VS. Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex. J Neurosci. 2012 Apr 4;32(14):4959-71. [ PDF ]
  95. Tan KR, Yvon C, Turiault M, Mirzabekov JJ, Doehner J, Labouèbe G, Deisseroth K, Tye KM, Lüscher C. GABA neurons of the VTA drive conditioned place aversion. Neuron. 2012 Mar 22;73(6):1173-83. Epub 2012 Mar 21. [ PDF | Supplemental Information ]
  96. Watanabe HC, Welke K, Schneider F, Tsunoda S, Zhang F, Deisseroth K, Hegemann P, Elstner M. Structural model of channelrhodopsin. J Biol Chem. 2012 Mar 2;287(10):7456-66. Epub 2012 Jan 11. [ PDF ]
  97. Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O. Crystal structure of the channelrhodopsin light-gated cation channel. Nature. 2012 Jan 22;482(7385):369-74. [ PDF | Supplemental Information | News & Views ]
  98. Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K. The microbial opsin family of optogenetic tools. Cell. 2011 Dec 23;147(7):1446-57. [ PDF | Supplemental Information ]
  99. Witten IB, Steinberg EE, Lee SY, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C, Stuber GD, Tye KM, Janak PH, Deisseroth K. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron. 2011 Dec 8;72(5):721-33. [ PDF | Supplemental Information ]
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  101. Anikeeva P, Andalman AS, Witten I, Warden M, Goshen I, Grosenick L, Gunaydin LA, Frank LM, Deisseroth K. Optetrode: a multichannel readout for optogenetic control in freely moving mice. Nature Neuroscience. 2011 Dec 4;15(1):163-70. [ PDF | SolidWorks File ]
  102. Zhao S, Ting JT, Atallah HE, Qiu L, Tan J, Gloss B, Augustine GJ, Deisseroth K, Luo M, Graybiel AM, Feng G. Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat Methods. 2011 Sep;8(9):745-52. [ PDF | Supplemental Information ]
  103. Wang J, Wagner F, Borton DA, Zhang J, Ozden I, Burwell RD, Nurmikko AV, van Wagenen R, Diester I, Deisseroth K. Integrated device for combined optical neuromodulation and electrical recording for chronic in vivo applications. J Neural Eng. 2012 Feb;9(1):016001. Epub 2011 Dec 7. [ PDF ]
  104. Goshen I, Brodsky M, Prakash R, Wallace J, Gradinaru V, Ramakrishnan C, Deisseroth K. Dynamics of Retrieval Strategies for Remote Memories. Cell. 2011 Oct 28;147(3):678-89. Epub 2011 Oct 20. [ PDF | Comment | Nature Reviews Neuroscience | Trends in Cognitive Sciences ]
  105. Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P, Deisseroth K. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature. 2011 Jul 27;477(7363):171-8. [ PDF | Supplement | News & Views ]
  106. Yizhar O, Fenno LE, Davidson TJ, Mogri M, Deisseroth K. Optogenetics in Neural Systems. Neuron. 2011 July;72:9-34. [ PDF ]
  107. Fenno LE, Yizhar O, Deisseroth K. The development and application of optogenetics. Annual Review of Neuroscience. 2011 July;34:389-412. [ PDF ]
  108. Stuber G., Sparta D., Stamatakis A.M., van Leeuwen W.A., Hardjoprajitno J.E., Cho S., Tye K.M., A. Kempadoo K.A., Zhang F., Deisseroth D., Bonci A. Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. Nature. 2011 Jun 29;475(7356):377-80. [ PDF | Supplement ]
  109. Tye KM, Prakash R, Kim SY, Fenno LE, Grosenick L, Zarabi H, Thompson KR, Gradinaru V, Ramakrishnan C, Deisseroth K. Amygdala circuitry mediating reversible and bidirectional control of anxiety. Nature. Mar 17;471(7338):358-62. Epub 2011 Mar 9. [ PDF | Supplement | Supplementary Movie ]
  110. Berndt A, Schoenenberger P, Mattis J, Tye KM, Deisseroth K, Hegemann P, Oertner TG. High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7595-600. Epub 2011 Apr 19. [ PDF ]
  111. Carlén M, Meletis K, Siegle JH, Cardin JA, Futai K, Vierling-Claassen D, Rühlmann C, Jones SR, Deisseroth K, Sheng M, Moore CI, Tsai LH. A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior. Mol Psychiatry. 2012 May;17(5):537-48. Epub 2011 Apr 5. [ PDF ]
  112. Pagliardini S, Janczewski WA, Tan W, Dickson CT, Deisseroth K, Feldman JL. Active expiration induced by excitation of ventral medulla in adult anesthetized rats. J Neurosci. 2011 Feb 23;31(8):2895-905. [ PDF ]
  113. Tønnesen J, Parish CL, Sørensen AT, Andersson A, Lundberg C, Deisseroth K, Arenas E, Lindvall O, Kokaia M. Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. PLoS One. 2011 Mar 4;6(3):e17560. [ PDF ]
  114. Diester I, Kaufman MT, Mogri M, Pashaie R, Goo W, Yizhar O, Ramakrishnan C, Deisseroth K, Shenoy KV. An optogenetic toolbox designed for primates. Nat Neuro. 2011 Mar;14(3):387-97. Epub 2011 Jan 30. [ PDF ]
  115. Deisseroth, K. Optogenetics. Nat Methods. 2011 Jan;8(1):26-9. Epub 2010 Dec 20. [ PDF | Nature Method of the Year Primer ]
  116. Brown MT, Bellone C, Mameli M, Labouèbe G, Bocklisch C, Balland B, Dahan L, Luján R, Deisseroth K, Lüscher C. Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation. PLoS One. 2010 Dec 31;5(12):e15870. [ PDF ]
  117. Witten IB, Lin SC, Brodsky M, Prakash R, Diester I, Anikeeva P, Gradinaru V, Ramakrishnan C, Deisseroth K. Cholinergic interneurons control local circuit activity and cocaine conditioning. Science. 2010 Dec 17;330(6011):1677-81. [ PDF | Supplement ]
  118. Covington HE 3rd, Lobo MK, Maze I, Vialou V, Hyman JM, Zaman S, LaPlant Q, Mouzon E, Ghose S, Tamminga CA, Neve RL, Deisseroth K, Nestler EJ. Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J Neurosci. 2010 Dec 1;30(48):16082-90. [ PDF ]
  119. Stroh A, Tsai HC, Ping Wang L, Zhang F, Kressel J, Aravanis A, Santhanam N, Deisseroth K, Konnerth A, Schneider MB. Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells. 2010 Nov 18. [ PDF ]
  120. Ciocchi S, Herry C, Grenier F, Wolff SB, Letzkus JJ, Vlachos I, Ehrlich I, Sprengel R, Deisseroth K, Stadler MB, Müller C, Lüthi A. Encoding of conditioned fear in central amygdala inhibitory circuits. Nature. 2010 Nov 11. [ PDF ]
  121. Haubensak W, Kunwar PS, Cai H, Ciocchi S, Wall NR, Ponnusamy R, Biag J, Dong HW, Deisseroth K, Callaway EM, Fanselow MS, Lüthi A, Anderson DJ. Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature. 2010 Nov 11;468(7321):270-6. [ PDF ]
  122. Carter ME, Yizhar O, Chikahisa S, Nguyen H, Adamantidis A, Nishino S, Deisseroth K, de Lecea L. Tuning arousal with optogenetic modulation of locus coeruleus neurons. Nat Neurosci. 2010 Dec;13(12):1526-33. Epub 2010 Oct 31. [ PDF ]
  123. Deisseroth K. Controlling the brain with light. Sci Am. 2010 Nov;303(5):48-55. [ Link | PDF ]
  124. Lobo MK, Covington HE 3rd, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, Nestler EJ. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science. 2010 Oct 15;330(6002):385-90. [ PDF ]
  125. Llewellyn ME, Thompson KR, Deisseroth K, Delp SL. Orderly recruitment of motor units under optical control in vivo. Nat Med. 2010 Oct;16(10):1161-5. Epub 2010 Sep 26. [ PDF ]
  126. Weick JP, Johnson MA, Skroch SP, Williams JC, Deisseroth K, Zhang SC. Functional control of transplantable human ESC-derived neurons via optogenetic targeting. Stem Cells. 2010 Nov;28(11):2008-16. [ PDF ]
  127. Gourine AV, Kasymov V, Marina N, Tang F, Figueiredo MF, Lane S, Teschemacher AG, Spyer KM, Deisseroth K, Kasparov S. Astrocytes control breathing through pH-dependent release of ATP. Science. 2010 Jul 30;329(5991):571-5. Epub 2010 Jul 15. [ PDF ]
  128. Shoham S, Deisseroth K. Special issue on optical neural engineering: advances in optical stimulation technology. J Neural Eng. 2010 Aug;7(4):040201. Epub 2010 Jul 19. [ PDF ]
  129. Johansen JP, Hamanaka H, Monfils MH, Behnia R, Deisseroth K, Blair HT, LeDoux JE. Optical activation of lateral amygdala pyramidal cells instructs associative fear learning. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12692-7. Epub 2010 Jun 25. [ PDF ]
  130. Kravitz AV, Freeze BS, Parker PR, Kay K, Thwin MT, Deisseroth K, Kreitzer AC. Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature. 2010 Jul 29;466(7306):622-6. Epub 2010 Jul 7. [ PDF ]
  131. Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B. Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science. 2010 Jul 23;329(5990):413-7. Epub 2010 Jun 24. [ PDF ]
  132. Tecuapetla F, Patel JC, Xenias H, English D, Tadros I, Shah F, Berlin J, Deisseroth K, Rice ME, Tepper JM, Koos T. Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens. J Neurosci. 2010 May 19;30(20):7105-10. [ PDF ]
  133. Jin Hyung Lee, Remy Durand, Viviana Gradinaru, Feng Zhang, Inbal Goshen, Dae-Shik Kim, Lief E. Fenno, Charu Ramakrishnan & Karl Deisseroth Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature. 2010 Jun 10;465(7299):788-92. [ PDF | Supplement | News & Views ]
  134. Gradinaru V, Zhang, F, Ramakrishnan C, Mattis J, Prakash R, Diester I, Goshen I, Thompson K, Deisseroth K. Molecular and Cellular Approaches for Diversifying and Extending Optogenetics. Cell. Apr 2;141(1):154-65. Epub 2010 Mar 18. [ PDF with Supplementary Material | Commentary ]
  135. Zhang F, Gradinaru V, Adamantidis AR, Durand R, Airan RD, de Lecea L, Deisseroth K. Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. Nat Protoc. 2010 Mar;5(3):439-56. Epub 2010 Feb 18. [ PDF ]
  136. Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nat Protoc. 2010 Feb;5(2):247-54. Epub 2010 Jan 21. [ PDF ]
  137. Gunaydin LA, Yizhar O, Berndt A, Sohal VS, Deisseroth K, Hegemann P. Ultrafast optogenetic control. Nat Neurosci. 2010 Mar;13(3):387-92. Epub 2010 Jan 17. [ PDF | Supplementary Materials ]
  138. Zhu P, Narita Y, Bundschuh ST, Fajardo O, Schärer YP, Chattopadhyaya B, Bouldoires EA, Stepien AE, Deisseroth K, Arber S, Sprengel R, Rijli FM, Friedrich RW. Optogenetic Dissection of Neuronal Circuits in Zebrafish using Viral Gene Transfer and the Tet System. Front Neural Circuits. 2009 Dec 11;3:21. [ PDF ]
  139. Zhang J, Laiwalla F, Kim JA, Urabe H, Van Wagenen R, Song YK, Connors BW, Zhang F, Deisseroth K, Nurmikko AV. Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue. J Neural Eng. 2009 Oct;6(5):055007. Epub 2009 Sep 1. [ PDF ]
  140. Carter ME, Adamantidis A, Ohtsu H, Deisseroth K, de Lecea L. Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions. J Neurosci. 2009 Sep 2;29(35):10939-49. [ PDF ]
  141. Tønnesen J, Sørensen AT, Deisseroth K, Lundberg C, Kokaia M. Optogenetic control of epileptiform activity. PNAS 2009 Jul 21;106(29):12162-7. Epub 2009 Jul 6. [ PDF ]
  142. Sohal VS, Zhang F, Yizhar O, Deisseroth K. Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature. 2009 Jun 4;459(7247):698-702. Epub 2009 Apr 26. [ PDF | Supplementary Materials ]
  143. Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature. 2009 Jun 4;459(7247):663-7. Epub 2009 Apr 26. [ PDF ]
  144. Tsai HC, Zhang F, Adamantidis A, Stuber GD, Bonci A, de Lecea L, Deisseroth K. Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning. Science. 2009 May 22;324(5930):1080-4. Epub 2009 Apr 23. [ PDF | Supplementary Material ]
  145. Zimmermann G, Wang LP, Vaughan AG, Manoli DS, Zhang F, Deisseroth K, Baker BS, Scott MP. Manipulation of an innate escape response in Drosophila: photoexcitation of acj6 neurons induces the escape response. PLoS ONE. 2009;4(4):e5100. Epub 2009 Apr 2. [ PDF ]
  146. Gradinaru V, Mogri M, Thompson KR, Henderson JM, Deisseroth K. Optical deconstruction of parkinsonian neural circuitry. Science. 2009 Apr 17;324(5925):354-9. Epub 2009 Mar 19. [ PDF | Supplementary Material | NewsFocus ]
  147. Airan RD, Thompson KR, Fenno LE, Bernstein H, Deisseroth K. Temporally precise in vivo control of intracellular signalling. Nature. 2009 Apr 23;458(7241):1025-9. Epub 2009 Mar 18. [ PDF | Supplementary Materials | News and Views ]
  148. Berndt A, Yizhar O, Gunaydin LA, Hegemann P, Deisseroth K. Bi-stable neural state switches. Nat Neurosci. 2009 Feb;12(2):229-34. Epub 2008 Dec 8. [ PDF ]
  149. Zhao S, Cunha C, Zhang F, Liu Q, Gloss B, Deisseroth K, Augustine GJ, Feng G. Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol. 2008 Aug;36(1-4):141-54. Epub 2008 Oct 17. [ PDF ]
  150. Douglass AD, Kraves S, Deisseroth K, Schier AF, Engert F. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Curr Biol. 2008 Aug 5;18(5):1133-7. [ PDF ]
  151. Gradinaru V, Thompson KR, Deisseroth K. eNpHR: aNatronomonashalorhodopsin enhanced for optogenetic applications. Brain Cell Biol. 2008 Aug;36(1-4):129-39. Epub 2008 Aug 2. [ PDF ]
  152. Schneider MB, Gradinaru V, Zhang F, Deisseroth K. Controlling neuronal activity. Am J Psychiatry. 2008 May;165(5):562. [ PDF ]
  153. Zhang F, Prigge M, Beyriere F, Tsunoda SP, Mattis J, Yizhar O, Hegemann P, Deisseroth K. Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nat Neurosci. 2008 Jun;11(6):631-3. Epub 2008 Apr 23. [ PDF ]
  154. Gradinaru V, Thompson KR, Zhang F, Mogri M, Kay K, Schneider MB, Deisseroth K. Targeting and readout strategies for fast optical neural control in vitro and in vivo. J Neurosci. 2007 Dec 26;27(52):14231-8. [ PDF | Thy-1::ChR2-EYFP Mouse | Wildtype Mouse Control ]
  155. Airan RD, Hu ES, Vijaykumar R, Roy M, Meltzer LA, Deisseroth K. Integration of light-controlled neuronal firing and fast circuit imaging. Curr Opin Neurobiol. 2007 Dec 17. [ PDF ]
  156. Adamantidis AR, Zhang F, Aravanis AM, Deisseroth K, de Lecea L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature. 2007 Nov 15;450(7168):420-4. Epub 2007 Oct 17. [ PDF ]
  157. Aravanis A, Wang LP, Zhang F, Meltzer L, Mogri M, Schneider MB, Deisseroth K. An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J. Neural Eng. 2007 Sep;4(3):S143-56. Epub 2007 May 31. [ PDF | Cover Image ]
  158. Zhang F, Aravanis AM, Adamantidis A, de Lecea L, Deisseroth K. Circuit-breakers: optical technologies for probing neural signals and systems. Nat Rev Neurosci. 2007 Aug;8(8):577-81. [ PDF | Corrigendum | Cover Image ]
  159. Arenkiel BR, Peca J, Davison IG, Feliciano C, Deisseroth K, Augustine GJ, Ehlers MD, Feng G. In vivolight-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2. Neuron. 2007 Apr 19;54(2):205-18. [ PDF ]
  160. Wang H, Peca J, Matsuzaki M, Matsuzaki K, Noguchi J, Qiu L, Wang D, Zhang F, Boyden E, Deisseroth K, Kasai H, Hall WC, Feng G, Augustine GJ. High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proc Natl Acad Sci U S A. 2007 May 8;104(19):8143-8. Epub 2007 May 1. [ PDF ]
  161. Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, Watzke N, Wood PH, Bamberg E, Nagel G, Gottschalk A, Deisseroth K. Multimodal fast optical interrogation of neural circuitry. Nature. 2007 Apr 5;446:633-39. [ PDF | N&V; | 2007 Highlight ]
  162. Deisseroth K, Feng G, Majewska AK, Miesenbock G, Ting A, Schnitzer MJ. Next-generation optical technologies for illuminating genetically targeted brain circuits. J Neurosci. 2006 Oct 11; 26(41):10380-6. [ PDF ]
  163. Zhang F, Wang LP, Boyden ES, Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat Methods. 2006 Oct; 3(10):785-92. [ PDF ]
  164. Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci. 2005 Sep;8(9):1263-8. Epub 2005 Aug 14. [ PDF ]