Arches. Photo by Daniel Chia
HOPES: Huntington's Outreach Project for Education, at Stanford
Feb
07
2011

histone acetyltransferases

Enzymes that add an acetyl group to histones, causing the histones to release the DNA they were binding. Transcription factors can then bind to the DNA, allowing gene transcription to occur. Patients with HD tend to have decreased histone acetyltransferase activity.