One of the transcription factors that needs CBP in order to bind to DNA. If P53 can’t access and bind DNA,there are problems with gene transcription and expression, which eventually leads to cell death.
An educational product of HOPES, not to be used in place of medical care. For more information about HOPES, click here. To contact HOPES with comments or questions, click here. Designed by Stephanie Liou. Based on Provision.