Publications Publications
Berns DS, DeNardo LA, Pederick DT, Luo L. (2018)
Teneurin-3 controls topographic circuit assembly in the hippocampus. Nature. 554(7692):328-333.
Abstract |[PDF]
Girasole AE, Lum MY, Nathaniel D, Bair-Marshall CJ, Guenthner CJ, Luo L, Kreitzer AC, Nelson AB (2018)
A Subpopulation of Striatal Neurons Mediates Levodopa-Induced Dyskinesia. Neuron 97(4):787-795.
Abstract |[PDF] |[Supp. data]
Li H, Horns F, Wu B, Xie Q, Li J, Li T, Luginbuhl DJ, Quake SR, Luo L. (2017)
Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-Cell RNA Sequencing. Cell 171(5):1206-1220.
Abstract |[PDF]
Hung LW, Neuner S, Polepalli JS, Beier KT, Wright M, Walsh JJ, Lewis EM, Luo L, Deisseroth K, Dölen G, Malenka RC. (2017)
Gating of social reward by oxytocin in the ventral tegmental area. Science 357(6358):1406-1411.
Abstract |[PDF] |[Supp. data]
Allen WE, DeNardo LA, Chen MZ, Liu CD, Loh KM, Fenno LE, Ramakrishnan C, Deisseroth K, Luo L. (2017)
Thirst-associated preoptic neurons encode an aversive motivational drive. Science 357(6356):1149-1155.
Abstract |[PDF] |[Supp. data]
Beier KT, Kim CK, Hoerbelt P, Hung LW, Heifets BD, DeLoach KE, Mosca TJ, Neuner S, Deisseroth K, Luo L, Malenka RC. (2017)
Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature 549(7672):345-350.
Abstract |[PDF]
Friedman DA, Gordon DM, Luo L. (2017)
The MutAnts Are Here. Cell 170(4):601-602.
Li J, Luo L. (2017)
Neurobiology: A bitter-sweet symphony. Nature 548(7667):285-287.
Wu B, Li J, Chou YH, Luginbuhl D, Luo L. (2017)
Fibroblast growth factor signaling instructs ensheathing glia wrapping of Drosophila olfactory glomeruli. Proc Natl Acad Sci 114(29):7505-7512.
Abstract |[PDF] |[PDF+Supp. data]
Mosca TJ, Luginbuhl DJ, Wang IE, Luo L. (2017)
Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons. Elife 6:e27347.
Abstract |[PDF]
DeNardo L, Luo L. (2017)
Genetic strategies to access activated neurons. Curr Opin Neurobiol. 45:121-129.
Abstract |[PDF]
Lasrado R, Boesmans W, Kleinjung J, Pin C, Bell D, Bhaw L, McCallum S, Zong H, Luo L, Clevers H, Vanden Berghe P, Pachnis V. (2017)
Lineage-dependent spatial and functional organization of the mammalian enteric nervous system. Science 356(6339):722-726.
Abstract |[PDF] |[PDF+Supp. data]
Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. (2017)
Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex. Neuron 94(4):891-907
Abstract |[PDF] |[PDF+Supp. data]
Chung S, Weber F, Zhong P, Tan CL, Nguyen TN, Beier KT, Hörmann N, Chang WC, Zhang Z, Do JP, Yao S, Krashes MJ, Tasic B, Cetin A, Zeng H, Knight ZA, Luo L, Dan Y. (2017)
Identification of preoptic sleep neurons using retrograde labelling and gene profiling. Nature 545(7655):477-481.
Abstract |[PDF]
Yackle K, Schwarz LA, Kam K, Sorokin JM, Huguenard JR, Feldman JL, Luo L, Krasnow MA. (2017)
Breathing control center neurons that promote arousal in mice. Science 355(6332):1411-1415.
Abstract |[PDF] |[PDF+Supp. data]
Wagner MJ, Kim TH, Savall J, Schnitzer MJ, Luo L. (2017)
Cerebellar granule cells encode the expectation of reward. Nature 544(7648):96-100.
Abstract |[PDF]
François A, Low SA, Sypek EI, Christensen AJ, Sotoudeh C, Beier KT, Ramakrishnan C, Ritola KD, Sharif-Naeini R, Deisseroth K, Delp SL, Malenka RC, Luo L, Hantman AW, Scherrer G. (2017)
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins. Neuron 93(4): 822-839
Abstract |[PDF] |[PDF+Supp. data]
Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L. (2016)
Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron Epub 2016 Sep 29.
Abstract |[PDF] |[PDF+Supp. data]
Do JP, Xu M, Lee SH, Chang WC, Zhang S, Chung S, Yung TJ, Fan JL, Miyamichi K, Luo L, Dan Y. (2016)
Cell type-specific long-range connections of basal forebrain circuit. eLife 5:e13214.
Abstract |[PDF]
Luo L. (2016)
Q&A. Neuron 91(3):508-510.
Ye L, Allen WE, Thompson KR, Tian Q, Hsueh B, Ramakrishnan C, Wang AC, Jennings JH, Adhikari A, Halpern CH, Witten IB, Barth AL, Luo L, McNab JA, Deisseroth K. (2016)
Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences. Cell 165(7):1776-88.
Abstract |[PDF] |[PDF+Supp. data]
Wu B, Luo L, Gao XJ. (2016)
Cas9-triggered chain ablation of cas9 as a gene drive brake. Nat Biotechnol. 34(2):137-8
[PDF] |[PDF+Supp. data]
Schwarz LA, Luo L. (2015)
Organization of the locus coeruleus-norepinephrine system. Current Biology 25(21):R1051-1056.
Abstract |[PDF]
DeNardo LA, Berns DS, DeLoach K, Luo L. (2015)
Connectivity of mouse somatosensory and prefrontal cortex examined with trans-synaptic tracing. Nat Neurosci. Epub 2015 Oct 12.
Abstract |[PDF] |[PDF+Supp. data]
Xu M, Chung S, Zhang S, Zhong P, Ma C, Chang WC, Weissbourd B, Sakai N, Luo L, Nishino S, Dan Y. (2015)
Basal forebrain circuit for sleep-wake control. Nat Neurosci. Epub 2015 Oct 12.
Abstract |[PDF] |[PDF+Supp. data]
Weber F, Chung S, Beier KT, Xu M, Luo L, Dan Y. (2015)
Control of REM sleep by ventral medulla GABAergic neurons. Nature Epub 2015 Oct 7.
Abstract |[PDF] |[PDF+Supp. data]
Huang ZJ, Luo L. (2015)
It takes the world to understand the brain. Science 350(6256):42-4.
Lerner TN, Shilyansky C, Davidson TJ, Evans KE, Beier KT, Zalocusky KA, Crow AK, Malenka RC, Luo L, Tomer R, Deisseroth K. (2015)
Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits. Cell 162(3).
Abstract |[PDF] |[PDF+Supp. data]
Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L, Gao XJ, Kremer EJ, Malenka RC, Luo L. (2015)
Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping. Cell 162(3).
Abstract |[PDF] |[PDF+Supp. data]
Schwarz LA, Miyamichi K, Gao XJ, Beier KT, Weissbourd B, DeLoach KE, Ren J, Ibanes S, Malenka RC, Kremer EJ, Luo L. (2015)
Viral-genetic tracing of the input-output organization of a central noradrenaline circuit. Nature Epub 2015 Jul 1.
Abstract |[PDF]
Callaway EM, Luo L (2015)
Monosynaptic Circuit Tracing with Glycoprotein-Deleted Rabies Viruses. J Neurosci. 35(24):8979-85.
Abstract |[PDF]
Mosca TJ (2015)
On the Teneurin track: a new synaptic organization molecule emerges. Front Cell Neurosci. 9:204.
Abstract |[PDF]
Gao XJ, Riabinina O, Li J, Potter CJ, Clandinin TR, Luo L (2015)
A transcriptional reporter of intracellular Ca2+ in Drosophila. Nat Neurosci. Epub 2015 May 11.
Abstract |[PDF] |[PDF+Supp. data]
Gao XJ, Clandinin TR, Luo L (2015)
Extremely sparse olfactory inputs are sufficient to mediate innate aversion in Drosophila. PLoS One 10(4):e0125986.
Abstract |[PDF]
Pearce MM, Spartz EJ, Hong W, Luo L, Kopito RR (2015)
Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain. Nat Commun. 6:6768
Abstract |[PDF] |[PDF+Supp. data]
Ward A, Hong W, Favaloro V, Luo L (2015)
Toll receptors instruct axon and dendrite targeting and participate in synaptic partner matching in a Drosophila olfactory circuit. Neuron 85(5):1013-28.
Abstract |[PDF] |[PDF+Supp. data]
Allen WE, Luo L (2015)
Intersectional illumination of neural circuit function. Neuron 85(5):889-92.
Lammel S, Steinberg EE, Földy C, Wall NR, Beier K, Luo L, Malenka RC (2015)
Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons. Neuron 85(2):429-38.
Abstract |[PDF] |[PDF+Supp. data]
Riabinina O, Luginbuhl D, Marr E, Liu S, Wu MN, Luo L, Potter CJ (2015)
Improved and expanded Q-system reagents for genetic manipulations. Nature Methods
Abstract |[PDF] |[PDF+Supp. data]
Gao P, Postiglione MP, Krieger TG, Hernandez L, Wang C, Han Z, Streicher C, Papusheva E, Insolera R, Chugh K, Kodish O, Huang K, Simons BD, Luo L, Hippenmeyer S, Shi SH (2014)
Deterministic progenitor behavior and unitary production of neurons in the neocortex. Cell 159(4):775-88.
Abstract |[PDF] |[PDF+Supp. data]
Adam Y, Livneh Y, Miyamichi K, Groysman M, Luo L, Mizrahi A (2014)
Functional transformations of odor inputs in the mouse olfactory bulb. Front Neural Circuits 8:129.
Abstract |[PDF]
Joo W, Hippenmeyer S, Luo L (2014)
Dendrite morphogenesis depends on relative levels of NT-3/TrkC signaling. Science 346(6209):626-9.
Abstract |[PDF] |[Full text + link to supplement]
Adelson JD, Sapp RW, Brott BK, Lee H, Miyamichi K, Luo L, Cheng S, Djurisic M, Shatz CJ (2014)
Developmental Sculpting of Intracortical Circuits by MHC Class I H2-Db and H2-Kb. Cerebral Cortex 2014.
Abstract |[PDF]
Mosca TJ, Luo L (2014)
Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins. Elife 2014 3:e03726.
Abstract |[PDF]
Zhang S, Xu M, Kamigaki T, Hoang Do JP, Chang WC, Jenvay S, Miyamichi K, Luo L, Dan Y (2014)
Long-range and local circuits for top-down modulation of visual cortex processing. Science 345(6197):660-5.
Abstract |[PDF] |[PDF+Supp. data]
Weissbourd B, Ren J, DeLoach KE, Guenthner CJ, Miyamichi K, Luo L (2014)
Presynaptic partners of dorsal raphe serotonergic and GABAergic neurons. Neuron 83(3):645-62.
Abstract |[PDF] |[PDF+Supp. data] |[Tracing images]
Guenther CA, Tasic B, Luo L, Bedell MA, Kingsley DM (2014)
A molecular basis for classic blond hair color in Europeans. Nat Genet. 46(7):748-52.
Abstract |[PDF] |[PDF+Supp. data]
Ali SR, Hippenmeyer S, Saadat LV, Luo L, Weissman IL, Ardehali R (2014)
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. PNAS 111(24):8850-5.
Abstract |[PDF] |[PDF+Supp. data]
Espinosa JS, Tea JS, Luo L (2014)
Mosaic analysis with double markers (MADM) in mice. Cold Spring Harb Protoc. (2):182-9
Abstract |[PDF]
Hong W, Luo L (2014)
Genetic control of wiring specificity in the fly olfactory system. Genetics 196(1):17-29
Abstract |[PDF]
Miyamichi K, Shlomai-Fuchs Y, Shu M, Weissbourd BC, Luo L, Mizrahi A (2013)
Dissecting local circuits: parvalbumin interneurons underlie broad feedback control of olfactory bulb output. Neuron 80(5):1232-45.
Abstract |[PDF] |[PDF+Supp. data]
Sinha S, Liang L, Ho ET, Urbanek KE, Luo L, Baer TM, Schnitzer MJ (2013)
High-speed laser microsurgery of alert fruit flies for fluorescence imaging of neural activity. PNAS 110(46):18374-9
Abstract |[PDF] |[PDF+Supp. data]
Liang L, Li Y, Potter CJ, Yizhar O, Deisseroth K, Tsien RW, Luo L (2013)
GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons. Neuron 79(5):917-31.
Abstract |[PDF] |[PDF+Supp. data]
Gao XJ, Potter CJ, Gohl DM, Silies M, Katsov AY, Clandinin TR, Luo L (2013)
Specific Kinematics and Motor-Related Neurons for Aversive Chemotaxis in Drosophila. Curr Biol. 23(13):1163-1172.
Abstract |[PDF] |[PDF+Supp. data]
Guenthner CJ, Miyamichi K, Yang HH, Heller HC, Luo L (2013)
Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations. Neuron 78(5):773-84.
Abstract |[PDF] |[PDF+Supp. data]
Joo WJ, Sweeney LB, Liang L, Luo L (2013)
Linking cell fate, trajectory choice, and target selection: genetic analysis of sema-2b in olfactory axon targeting. Neuron 78(4):673-86.
Abstract |[PDF] |[PDF+Supp. data]
Yu XM*, Gutman I*, Mosca TJ*, Iram T, Ozkan E, Garcia KC, Luo L, Schuldiner O (2013)
Plum, an Immunoglobulin Superfamily Protein, Regulates Axon Pruning by Facilitating TGF-Beta Signaling. Neuron 78(3):456-68.
Abstract |[PDF] |[PDF+Supp. data]
Sekine SU, Haraguchi S, Chao K, Kato T, Luo L, Miura M, Chihara T (2013)
Meigo governs dendrite targeting specificity by modulating Ephrin level and N-glycosylation. Nat Neurosci. 16(6):683-91.
Abstract |[PDF] |[PDF+Supp. data]
Hippenmeyer S, Johnson RL, Luo L (2013)
Mosaic Analysis with Double Markers Reveals Cell-Type-Specific Paternal Growth Dominance. Cell Rep. Epub 2013 Feb 26.
Abstract |[PDF] |[PDF+Supp. data]
Yu XM and Luo L (2012)
Neuroscience. dSarm-ing axon degeneration. Science 337(6093): 418-9. (preview)
Abstract |[PDF]
Chen S, Spletter M, Ni X, White KP, Luo L, Long M (2012)
Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Cell Reports 1(2): 118-32.
Abstract |[PDF]
Berdnik D, Favaloro V, Luo L (2012)
The SUMO Protease Verloren Regulates Dendrite and Axon Targeting in Olfactory Projection Neurons. J. Neurosci 32(24): 8331-8340.
Abstract |[PDF]
Tasic B, Miyamichi K, Hippenmeyer S, Dani VS, Zeng H, Joo W, Zong H, Chen-Tsai Y, Luo L (2012)
Extensions of MADM (mosaic analysis with double markers) in mice. PLoS One Epub 2012 Mar 27.
Abstract |[PDF] |[PDF+Supp. data]
Yang SB, McLemore KD, Tasic B, Luo L, Jan YN, Jan LY (2012)
Kv1.1-dependent Control of Hippocampal Neuron Number as Revealed by Mosaic Analysis with Double Markers (MADM). J. Physiology 590: 2645-2658.
Abstract |[PDF]
Mosca TJ*, Hong W*, Dani VS, Favaloro V, Luo L (2012)
Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice. Nature Epub 2012 Mar 18.
Abstract |[PDF] |[PDF+Supp. data]
Hong W, Mosca TJ, Luo L (2012)
Teneurins instruct synaptic partner matching in an olfactory map. Nature Epub 2012 Mar 18.
Abstract |[PDF] |[PDF+Supp. data]
Wei X, Potter CJ, Luo L, Shen K (2012)
Controlling gene expression with the Q repressible binary expression system in Caenorhabditis elegans. Nat Methods. Epub 2012 Mar 11.
Abstract |[PDF+Supp. data]
Sweeney LB, Chou YH, Wu Z, Joo W, Komiyama T, Potter CJ, Kolodkin AL, Garcia KC, Luo L (2011)
Secreted Semaphorins from Degenerating Larval ORN Axons Direct Adult Projection Neuron Dendrite Targeting. Neuron 72(5):734-47.
Abstract |[PDF] |[PDF+Supp. data]
de Wit J*, Hong W*, Luo L, Ghosh A (2011)
Role of leucine-rich repeat proteins in the development and function of neural circuits. Annu. Rev. Cell Dev. Biol. 27:697-729. Epub 2011 Jul 5.
Abstract |[PDF]
Liu C, Sage JC, Miller MR, Verhaak RGW, Hippenmeyer S, Vogel H, Foreman O, Bronson RT, Nishiyama A, Luo L, Zong H (2011)
Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma. Cell 146(2):209-21.
Abstract |[PDF] |Commentary
Potter CJ and Luo L (2011)
Using the Q system in Drosophila melanogaster. Nat. Protoc. 6(8):1105-20.
Abstract |[PDF]
Wu Z, Sweeney LB, Ayoob JC, Chak K, Andreone BJ, Ohyama T, Kerr R, Luo L, Zlatic M, Kolodkin AL. (2011)
A combinatorial semaphorin code instructs the initial steps of sensory circuit assembly in the Drosophila CNS. Neuron 70(2):281-98.
Abstract |[PDF] |Commentary
Tasic B, Hippenmeyer S, Wang C, Gamboa M, Zong H, Chen-Tsai Y and Luo L (2011)
Site-specific integrase-mediated transgenesis in mice via pronuclear injection. PNAS 108(19):7902-7. Epub 2011 Apr 4.
Abstract |[PDF] |[PDF+Supp. Data] |Commentary
Tea JS and Luo L (2011)
The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting. Neural Dev. 2011 Feb 1;6:5.
Abstract |[PDF]
Miyamichi K, Amat F, Moussavi F, Wang C, Wickersham I, Wall NR, Taniguchi H, Tasic B, Huang ZJ, He Z, Callaway EM, Horowitz MA, Luo L (2010)
Cortical representations of olfactory input by trans-synaptic tracing. Nature. 472(7342):191-6. Epub 2010 Dec 22.
Abstract |[PDF+Supp. Data] |[PDF]
Lin S, Lai SL, Yu HH, Chihara T, Luo L and Lee T. (2010)
Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development. 137(1):43-51.
Abstract |[PDF]
Hippenmeyer S, Youn YH, Moon HM, Miyamichi K, Zong H, Wynshaw-Boris A and Luo L (2010)
Genetic mosaic dissection of lis1 and ndel1 in neuronal migration. Neuron 68(4):695-709
Abstract |[PDF] |[PDF+Supp. Data] |[Supp. Data] |[Movie 1] |[Movie 2]
Chou Y, Zheng X, Beachy PA, Luo L (2010)
Patterning axon targeting of olfactory receptor neurons by coupled hedgehog signaling at two distinct steps. Cell 142(6): 954-66
Abstract |[PDF+Supp. Data] |[PDF]
Luo L et al. (2010)
Ten years of Nature Reviews Neuroscience: insights from the highly cited. Nat. Rev. Neurosci. 11(10):718-26.
Abstract |[PDF]
Sweeney L and Luo L (2010)
‘Fore brain: a hint of the ancestral cortex. Cell 142(5): 679-81 (preview)
Abstract |[PDF]
Tea J, Chihara T and Luo L (2010)
Histone deacetylase Rpd3 regulates olfactory projection neuron dendrite targeting via the transcription factor Prospero. J. Neurosci. 30(29):9939-46.
Abstract |[PDF]
Li L, Tasic B, Micheva KD, Ivanov VM, Spletter ML, Smith SJ and Luo L (2010)
Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS ONE 5(7): e11503
Abstract |[PDF+Supp. Data] |[PDF]
Liang L and Luo L (2010)
The olfactory circuit of the fruit fly Drosophila melanogaster. Sci. China Life Sci. 53(4):472-84.
Potter CJ*, Tasic B*, Russler EV, Liang L, Luo L (2010)
The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis. Cell 141(3):536-48
Abstract |[PDF+Supp. Data] |[PDF] |[Supp. Data] |[flies@Bloomigton] |[DNA@Addgene] |[DNA sequence files - GenBank format]
Potter CJ and Luo L (2010)
Splinkerette PCR for mapping transposable elements in Drosophila. PLoS ONE 5(4):e10168.
Abstract |[PDF]
Chou YH*, Spletter ML*, Yaksi E*, Leong JC, Wilson RI, Luo L (2010)
Diversity and wiring variability of olfactory local interneurons in the Drosophila antennal lobe. Nat Neurosci. 13(4):439-49. Epub 2010 Feb 7.
Abstract |[PDF+Supp. Data] |[PDF] |[Supp. Data] |[Supp. Table 2] |[Supp. Table 3] |[LN Confocal Data - Flybrain@Stanford]
Hong W and Luo L (2009)
Dendritic tiling through TOR signalling. EMBO J. 28(24):3783-4. (preview)
Abstract |[PDF]
Miyamichi K and Luo L (2009)
Neuroscience. Brain wiring by presorting axons. Science, 325(5940):544-5. (preview)
Abstract |[PDF]
Hong W, Zhu H, Potter CJ, Barsh G, Kurusu M, Zinn K, Luo L (2009)
Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map. Nat. Neurosci. 12(12):1542-50
Abstract |[PDF+Supp. Data] |[PDF] |[Supp. Data]
Spletter ML and Luo L (2009)
A new family of odorant receptors in Drosophila. Cell, 136(1):23-5. (preview)
Abstract |[PDF]
Espinosa JS, Wheeler DG, Tsien RW, Luo L (2009)
Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B. Neuron, 62(2): 205-17
Abstract |[PDF + Supp. Data] |[PDF] |[Supp. Data]
Berdnik D, Fan AP, Potter CJ, Luo L (2008)
MicroRNA processing pathway regulates olfactory neuron morphogenesis. Curr. Biol. 18(22):1754-9.
Abstract |[PDF+Supp. Data] |[PDF] |[Supp. Data]
Potter, CJ and Luo L (2008)
Octopamine fuels fighting flies. Nat. Neurosci. 11(9):989-90. (comment)
Abstract |[PDF]
Hoopfer ED*, Penton A*, Watts RJ and Luo L (2008)
Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning. J. Neurosci. 28(24):6092-103.
Abstract |[PDF]
Luo L, Callaway EM and Svoboda K (2008)
Genetic dissection of neural circuits. Neuron 57: 634-60. (review)
Abstract |[PDF]
Espinosa JS and Luo L (2008)
Timing neurogenesis and differentiation: insights from quantitative clonal analyses of cerebellar granule cells. J. Neurosci. 28(10): 2301-12.
Abstract |[PDF]
Schuldiner O, Berdnik D, Levy JM, Wu JS, Luginbuhl D, Gontang AC, Luo L (2008)
piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning. Dev. Cell 14(2): 227-38.
Abstract |[PDF+Supp. Data] |[PDF] |[Supp. Data] |[Supp. Table 1] |[Supp. Table 2]
Luo L and Flanagan JG (2007)
Development of continuous and discrete neural maps. Neuron 56: 284-300. (review)
Abstract |[PDF]
Luo L (2007)
Fly MARCM and mouse MADM: Genetic methods of labeling and manipulating single neurons. Brain Res. Rev. 55(2): 220-7. (review)
Abstract |[PDF]
Muzumdar MD, Tasic B, Miyamichi K, Li L, Luo L (2007)
A global double-fluorescent Cre reporter mouse. Genesis 45(9): 593-605.
Abstract |[PDF]
Spletter ML, Liu J, Liu J, Su H, Giniger E, Komiyama T, Quake S, Luo L (2007)
Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Development 2: 14.
Abstract |[PDF] |[Supp. Data]
Chihara T, Luginbuhl D, Luo L (2007)
Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization. Nat. Neurosci. 110(7): 828-37.
Abstract |[PDF] |[Supp. Data]
Jefferis GSXE*, Potter CJ*, Chan AM, Marin EC, Rohlfing T, Maurer CR, and Luo L (2007)
Comprehensive maps of fly higher olfactory centres: spatially segregated fruit and pheromone representation. Cell 128: 1187-203.
Abstract |[PDF] |[Supp. Data] |[Flybrain @ Stanford]
Komiyama T, Sweeney LB, Schuldiner O, Garcia KC, and Luo L (2007)
Graded expression of Semephorin-1a cell-autonomously directs dendritic targeting of olfactory projection neurons. Cell 128: 399-410.
Abstract |[PDF] |[Supp. Data]
Komiyama T and Luo L (2007)
Intrinsic control of precise dendritic targeting by an ensemble of transcription factors. Current Biology 17(3): 278-85.
Abstract |[PDF] |[Supp. Data]
Muzumdar MD, Luo L, and Zong H (2007)
Modeling sporadic loss of heterozygosity in mice using Mosaic Analysis with Double Markers (MADM). PNAS 104(11): 4495-500.
Abstract |[PDF] |[Supp. Data]
Sweeney LB, Couto A, Chou Y-H, Berdnik D, Dickson BJ, Luo L, and Komiyama T (2007)
Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA mediated axon-axon interactions. Neuron 53: 185-200.
Abstract |[PDF] |[Supp. Data]
Wu J and Luo L (2006)
A protocol for mosaic analysis with a repressible cell marker (MARCM) in Drosophila. Nature Protocols 1(6): 2583-9. (protocol)
Wu J and Luo L (2006)
A Protocol for Dissecting and Immunostaining the Drosophila Brain. Nature Protocols 1(4): 2110-5. (protocol)
Hoopfer ED, McLaughlin T, Watts RJ, Oren Schuldiner O, O?Leary DDM, and Luo L (2006)
Wlds protection distinguishes axon degeneration following injury from naturally-occurring developmental pruning. Neuron 50: 883-95.
Abstract |[PDF] |[Supp. Data]
Berdnik D, Chihara T, Couto A, and Luo L (2006)
Wiring stability of the adult Drosophila olfactory circuit after lesion. J. Neurosci. 26(13): 3367-76.
Abstract |[PDF]
Zhu H, Hummel T, Clemens JC, Berdnik D, Zipursky SL, and Luo L (2006)
Dendritic patterning by Dscam and synaptic partner matching in the Drosophila antennal lobe. Nat. Neurosci. 9: 349-55.
Abstract |[PDF]
Komiyama T and Luo L (2006).
Development of wiring specificity in the olfactory system. Curr. Opin. Neurobiol. 16: 67-73. (review)
Abstract |[PDF]
Luo L (2005)
Developmental neuroscience: two gradients are better than one. Nature 439(7072): 23-4. (comment)
Abstract |[PDF]
Ramaekers A, Magnenat E, Marin EC, Gendre N, Jefferis GSXE, Luo L, and Stocker RF (2005)
Glomerular maps without cellular redundancy at successive levels of the Drosophila larval olfactory circuit. Current Biology 15(11): 982-92
Abstract |[PDF]
Zong H, Espinosa JS, Su HH, Muzumdar MD, and Luo L (2005)
Mosaic analysis with double markers in mice. Cell 121: 479-92.
Abstract |[PDF]
Luo L and O'Leary DDM (2005)
Axon retraction and degeneration in development and disease. Ann. Rev. Neurosci. 28: 127-56. (review)
Goldstein AYN, Jan YN, and Luo L (2005)
Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis. Proc. Natl. Acad. Sci. USA 102: 3834-9.
Abstract |[PDF]
Marin EC, Watts RJ, Takana NK, Ito K, and Luo L (2005)
Developmentally programmed remodelling of the Drosophila olfactory circuit. Development, 132: 725-37.
Abstract |[PDF]
Luo L (2004)
Single Neuron Labeling using Genetic Methods. (in Imaging Neurons, A Cold Spring Harbor Manual. Eds. Yuste R. and Konnerth A.) Cold Spring Harbor Laboratory Press
Jefferis GSXE and Luo L (2004)
The Development of the Olfactory System. (in Comprehensive Insect Physiology, Biochemistry, Pharmacology and Molecular Biology. Eds: Gilbert L. et al.) Elsevier
Denk W and Luo L (2004)
Overview: New Technology. Curr. Opin. Neurobiol. 14: 589-90.
Ng J and Luo L (2004)
Rho GTPases Regulate Axon Growth through Convergent and Divergent Signaling Pathways. Neuron 44(5): 779-93.
Abstract |[PDF]
Chihara T and Luo L (2004)
Like poles repel; molecular mechanisms of dendritic tiling. Cell 119(2): 148-9. (preview)
Abstract |[PDF]
Komiyama T, Carlson JR, and Luo L (2004)
Olfactory Receptor Neuron Axon Targeting: Intrinsic Transcriptional Control and Hierarchical Interactions. Nat. Neurosci. 7(8): 819-25.
Abstract |[PDF]
Watts RJ, Schuldiner O, Perrino J, Larsen C, and Luo L (2004)
Glia Engulf Degenerating Axons during Developmental Axon Pruning. Current Biology 14(8): 678-84.
Abstract |[PDF]
Zhu H and Luo L (2004)
Diverse functions of N-cadherin in dendritic and axonal terminal arborization of olfactory projection neurons. Neuron 42(1): 63-75.
Abstract |[PDF]
Jefferis GSXE, Komiyama T, and Luo L (2004)
Ca++ and CREST for Healthy Dendrites. Science 303: 179-81. (comment)
Abstract |[PDF]
Jefferis GSXE, Vyas RM, Berdnik D, Ramaekers A, Stocker RF, Tanaka N, Ito K, and Luo L (2004)
Developmental Origin of Wiring Specificity in the Olfactory System of Drosophila. Development 131: 117-30.
Abstract |[PDF]
Potter CJ and Luo L (2003)
Food for Thought: an Orphan Receptor Finds its Ligands. Nat. Neurosci. 11: 1119-20. (comment)
Abstract |[PDF]
Zhai Q, Wang J, Kim A, Liu Q, Watts R, Hoopfer E, Mitchison T, Luo L, and He Z (2003) Involvement of the Ubiquitin-Proteasome System in the Early Stages of Wallerian Degeneration. Neuron, 39: 217-25.
Abstract |[PDF]
Scott EK, Reuter J, and Luo L (2003) Dendritic Development of Drosophila High Order Visual System Neurons is Independent of Sensory Experience (2003) BMC Neuroscience 4:14.

Watts RJ, Hoopfer ED, and Luo L (2003)
Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system. Neuron 38(6):871-85.
Abstract |[PDF]
Scott E, Reuter J, and Luo L (2003)
Small GTPase Cdc42 is Required for Multiple Aspects of Dendritic Morphogenesis. J. Neurosci., 23(8): 3118-23.
Abstract |[PDF]
Reuter J, Nardine T, Penton A, Billuart P, Scott EK, Usui T, Uemura T, and Luo L (2003)
A Mosaic Genetic Screen for Genes Necessary for Drosophila Mushroom Body Neuronal Morphogenesis. Development, 130: 1203-13.
Abstract |[PDF]
Komiyama T, Johnson W, Luo L, and Jefferis GSXE (2003)
From Lineage to Wiring Specificity: POU Domain Transcription Factors Control Precise Connections of Drosophila Olfactory Projection Neurons. Cell, 112(2): 157-67.
Abstract |[PDF]
Luo L (2002)
Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Ann. Rev. Cell Dev. Biol. 18, 601-35. (review)
Abstract |[PDF]
Scott EK, Raabe T, and Luo L (2002)
Structure of the Vertical System and Horizontal System Neurons of the Lobula Plate in Drosophila. J. Comp. Neuro. 454, 470-81
Abstract |[PDF]
Marin E, Jefferis GSXE, Komiyama T, Zhu H, and Luo L (2002)
Representation of the glomerular olfactory map in the Drosophila brain. Cell, 109(2): 243-55.
Abstract |[PDF]
Ng J, Nardine T, Harms M, Tzu J, Goldstein A, Sun Y, Dietzl G, Dickson B, and Luo L (2002)
Rac GTPases control axon growth, guidance, and branching. Nature, 416: 442-7.
Abstract |[PDF]
Hakeda-Suzuki S, Ng J, Tzu J, Dietzl G, Sun Y, Harms M, Nardine T, Luo L, and Dickson B (2002)
Rac function and regulation during Drosophila development. Nature, 416: 438-42.
Abstract |[PDF]
Jefferis GSXE, Marin EC, Watts R, and Luo L (2002)
Development of neuronal connectivity in Drosophila antennal lobes and mushroom bodies. Curr. Opin. Neurobiol. 12, 80-6. (review)
Abstract |[PDF]
Baas PW and Luo L (2001)
Signaling at the growth cone: Cajal's scientific progeny meet in Madrid. Neuron, 32: 981-4. (meeting report)
Abstract |[PDF]
Luo L and Zong H (2001)
Single neuron labeling and genetic manipulation. Nat. Neurosci. 4 Supp 1: 1158-9. (review)
Abstract |[PDF]
Jefferis GSXE, Marin EC, Stocker RF, and Luo L (2001)
Target neuron prespecification in the olfactory map of Drosophila. Nature, 414: 204-8.
Abstract |[PDF]
Billuart P, Winter CG, Maresh A, Zhao X, and Luo L (2001)
Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway. Cell, 107(2): 195-207.
Abstract |[PDF]
Lee T and Luo L (2001)
Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends in Neurosciences, 24(5): 251-4. (review)
Abstract |[PDF] |[erratum]
Scott E and Luo L (2001)
How do dendrites take their shape? Nat. Neurosci., 4(4): 353-9. (review)
Abstract |[PDF]
Winter C, Wang B, Ballew A, Royou A, Karess R, Axelrod J, and Luo L (2001)
Drosophila Rho-asociated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell, 105(1): 81-91.
Abstract |[PDF]
Scott E, Lee T, and Luo L (2001)
enok Encodes a Drosophila Putative histone acetyltransferase required for mushroom body neuroblast proliferation. Current Biology, 11(2): 99-104.
Abstract |[PDF]
Lee T, Marticke S, Sung C, Robinow S, Luo L (2000)
Cell-autonomous requirement of the USP/EcR-B ecdysone receptor for mushroom body neuronal remodeling in Drosophila.Neuron, 28(3): 807-18.
Abstract |[PDF]
Luo L (2000)
Rho GTPases in neuronal morphogenesis. Nat. Rev. Neurosci., 1(3): 173-80. (review)
Abstract |[PDF]
Nakayama AY, and Luo L (2000)
Intracellular signaling pathways that regulate dendritic spine morphogenesis. Hippocampus, 10(5): 582-6. (review)
Liu Z, Steward R, and Luo L (2000)
Drosophila Lis1 is required for neuroblast proliferation, dendrite elaboration and axonal transport. Nat. Cell Biol., 2(11): 776-83.
Abstract |[PDF]
Luo L (2000)
Trio Quartet in D. (melanogaster). Neuron, 26: 1-2. (preview)
Abstract |[PDF]
Nakayama AY, Harms MB, and Luo L
Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons. J. Neurosci., 20 (14): 5329-38.
Abstract |[PDF]
Lee T, Winter C, Marticke SS, Lee A, and Luo L (2000)
Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis. Neuron, 25: 307-16.
Abstract |[PDF]
Lee T, Lee A, and Luo L (1999)
Development of Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a single neuroblast. Development, 126: 4065-76.
Abstract | [PDF]
Luo L, Lee T, Nardine T, Null B, and Reuter J (1999)
Using the MARCM system to positively mark mosaic clones in Drosophila. Dros. Info. Service, 82: 102-5.
Lee T, and Luo L (1999)
Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron, 22: 451-61.
Abstract | [PDF]
pre-1999, representative
Luo L, Hensch TK, Ackerman L, Barbel S, Jan LY, and Jan YN (1996)
Differential effects of the Rac GTPase on Purkinje cell axons, dendrites and dendritic spines. Nature 379: 837-40.
Abstract | [PDF]
Luo L, Liao YJ, Jan LY, and Jan YN (1994)
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes & Development, 8: 1787-802.
Luo L, Tully T, and White K (1992)
Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene. Neuron, 9: 595-605.

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