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Recent Abstracts
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Eric Lichtinger Velasco, Vytas Dargis-Robinson, B.S. and  Bruce MacIver (2010)  Increased GABA-B receptor inhibition contributes to isoflurane-induced depression of synapses. Soc. Neuroscience, 36


Bruce MacIver,  Youngjun  Na and Vytas Dargis-Robinson, B.S. (2010) GABA-B receptors located on CA1 dendrites appear to contribute most  to propofol-induced depression.  Anesthesiology, 104

Bruce MacIver,  Daniel Butler, Joshua Khani,  Lisa Rotenstein,  Gily Raz, Eric Lichtinger Velasco, Vytas Dargis-Robinson and Rona Giffard (2010) Removal of Calcium Significantly Enhances Ischemic Insult Recovery in Rat Hippocampal Brain Slices.  Anesthesiology, 104

Bruce MacIver, Eric Lichtinger Velasco and Vytas Dargis-Robinson  (2010) Isoflurane depresses Synaptic Trasnsmission by Enhancing GABA-B Receptor-Mediated  Inhibition. Anesthesiology, 104

MacIver, M.B., Jaffe, R.A. and Brock-Utne, J.G. (2010) Subthalamic neurons recorded in humans exhibit agent selective responses to sedatives. Winter Conference on Brain Research, 43.

Bruce MacIver, M.Sc., Ph.D. and Vytas Dargis-Robinson, B.S. (2009) GABA-A fast synapses contribute the vast majority to propofol-induced depression of CA1 neurons. Anesthesiology, 103

Vytas Dargis-Robinson, B.S. and Bruce MacIver, M.Sc., Ph.D. (2009) GABA-B-mediated Inhibition Contributes to Propofol-Induced Depression of Hippocampal Responses. Anesthesiology, 103

Bruce MacIver, M.Sc., Ph.D., John Brock-Utne, M.D., Ph.D. and Richard Jaffe, M.D., Ph.D.  (2009) Subthalamic neurons recorded in humans are differentially altered by propofol and remifentanil. Anesthesiology, 103

Bruce MacIver, M.Sc., Ph.D. and Steve Towers, Ph.D. (2009) Using isoflurane to probe dynamic properties of hippocampal gamma frequency EEG activity. Anesthesiology, 103

Rotenstein, R., Giffard, R.G. and MacIver, M.B. (2009) Elevated potassium associated with ischemia produces neuronal damage independent of calcium influx into hippocampal CA1 cells. Winter Conference on Brain Research, 42.

Towers, S.K and MacIver, M.B. (2008) Longer duration of inhibition in brain slices that generate gamma oscillations. Anesthesiology, 101.

Dargis-Robinson, V. and MacIver, M.B. (2008) Comparing the effectiveness and time course of several forms of synaptic inhibition. Anesthesiology, 101.

MacIver, M.B., Brock-Utne, J.G. and Jaffe, R.A. (2008) Multiple actions produced by propofol on subthalamic neurons recorded from humans. Soc. Neuroscience, 34.
 
Towers, S.K. and MacIver, M.B. (2008) Gamma oscillations and longer duration of paired pulse inhibition in horizontal versus coronal hippocampal slices. Soc. Neuroscience, 34.

Dargis-Robinson, V. and MacIver, M.B. (2008) We know which is faster, but which is stronger? Comparing GABA-A fast and GABA-A slow inhibition.

MacIver, M.B. (2008) Abused Inhalants May Interfere wth Learning by Disrupting Hippocampal Inhibitory Circuit Function.
Winter Conference on Brain Research, 41.

MacIver, M.B. (2007) Abused inhalant disruption of hippocampal circuit function.  Soc. Neuroscience, 33.

Sceniak, M.P. and MacIver, M.B. (2007) GABAa slow synaptic responses in rat visual cortex.  Soc. Neuroscience, 33.

Bieda, M, Su, H. and MacIver, M.B. (2007) Tonic and synaptic GABA-A receptors exhibit differential sensitivities to volatile vs IV anesthetics.
Soc. Neuroscience, 33.

Jaffe, R.A., Brock-Utne, J.G. and MacIver, M.B. (2007) Propofol produces sedation for human DBS electrode implants without altering subthalamic neuron electrophysiology. Soc. Neuroscience, 33.

Winegar, B.D. and MacIver, M.B. (2007) Propofol Actions on Spontaneous Firing of Subthalamic Nucleus Neurons Soc. Neuroscience, 33.

MacIver, M.B. (2007) EEG signals and IPSCs associated with unconsciousness: Timing is everything.  Winter Conference on Brain Research, 40.

MacIver, M.B. and J.G. Brock-Utne (2006) Comparison of propofol effects on human subthalamic vs thalamic neuron electrophysiology in vivo.  Anesthesiology, 99.

Henry Su, Mark C. Bieda and M. Bruce MacIver (2006) Anesthetics discriminate between tonic and synaptic GABA-A receptors on CA1 pyramidal neurons.  Anesthesiology, 99.

Bruce D. Winegar and M. Bruce MacIver (2006) Propofol prolongs interspike intervals in rat subthalamic nucleus neurons in brain slices.  Anesthesiology, 99.

Michael P. Sceniak and M. Bruce MacIver (2006) Slow GABAA synaptic transmission in the rat visual cortex.  Soc. Neuroscience, 32.

MacIver, M.B. (2006) Abused inhalants target specific subtypes of inhibitory nerve terminals on CA1 neurons. Soc. Neuroscience, 32.

Winegar, B.D. and M.B. MacIver (2006) propofol depresses spike firing in dopamine-sensitive rat subthalamic neurons.  Soc. Neuroscience, 32.

Sceniak, M. and MacIver, M.B. (2005) Urethane Anesthesia: A Novel and Specific Mechanism of Action. Anesthesiology, 98.
 
Winegar, B. and MacIver, M.B. (2005) Isoflurane Depression of Hippocampal Synapse Glutamate Release Does Not Involve Sodium Channel Block. Anesthesiology. 98.

Patricia A. Turnquist and M. Bruce MacIver (2005) Anesthetic block of LTP involves depression of NMDA EPSPs and enhanced GABA inhibition. Soc. Neuroscience, 31.

Bruce D. Winegar and Bruce M. MacIver (2005) Fiber volleys at hippocampal CA1 glutamate nerve terminals are insensitive to clinical concentrations of isoflurane.  Soc. Neuroscience, 31.

MacIver, M.B. (2004) Isoflurane depresses NMDA-mediated EPSPs at concentrations that block LTP and learning in rats.
Soc Neuroscience 30:854.6

MacIver, M.B. (2004) The Neurobiology of Consciousness. Winter Conference on Brain Research, 37; 111.

Choi, D., Turnquist, P.A., McDonald, M.A. and MacIver, M.B. (2003) Effects of Toluene on Hippocampal Synaptic Responses, Soc. Neuroscience, 29; 10.7.

Turnquist, P.A., Choi, D.S. and MacIver, M.B. (2003) Toluene Effects on Glutamate-Mediated Synaptic Responses.  Anesthesiology, 97.

McDonald, M.A., Turnquist, P.A., Springer, J.D. and MacIver, M.B. (2003) Ischemia-induced Potassium Ion Effects on Excitatory Synaptic transmission.  Anesthesiology, 97.

McDonald, M.A., Turnquist, P.A. and MacIver, M.B. (2003) Comparison of Halothane and Toluene Actions at GABA Synapses.  Anesthesiology, 97.

McDonald, M.A. and MacIver, M.B. (2003) Isoflurane Actions on Noradrenergic Inhibition of CA 1 Pyramidal Neurons.  Anesthesiology, 97.

MacIver M.B. (2003) Comparison of IV and Inhalational Anesthetic Actions at GABA synapses.  Winter Conference on Brain Research, 35, 55.

Cheung, K. H-T and MacIver, M.B. (2002)  Isoflurane-Induced Depression of Synaptic LTP does not Involve Post-NMDA Receptor Mediated Mechanisms.  Anesthesiology, 96: A815.

McDonald, M.A., Rastegar, J.C., Turnquist, P.A., and MacIver, M.B. (2002)  Ischemic Shock and High Potassium-Induced Depression of Synaptic Transmission.  Anesthesiology, 96: A718.

Turnquist, P.A., Bieda, M.C., Pittson, S., and MacIver, M.B. (2002)  Slow Diffusion Into Brain Slices Decreases the Apparent Potency of an Anesthetic. Anesthesiology, 96: A790.

Bieda, M.C. and MacIver, M.B. (2001) Propofol primarily targets GABA-gated chloride channels in hippocampal neurons.  Anesthesiology  (accepted).

Bieda, M.C. and MacIver, M.B. (2001) Propofol actions on hippocampal CA 1 inhibitory interneurons. Soc. Neuroscience (accepted)

Anderson, R.J., Hornung, B., Pittson, S., Monroe, F.A. and MacIver, M.B (2000)  Isoflurane blocks LTP of hippocampal CA1 neurons at concentrations that block recall during anesthesia.  Soc. Neuroscience, 26(1):1077 (#405.7).

Nishikawa, K. and MacIver, M.B. (2000)  Halothane produces disinhibition by depressing inhibitory interneurons in rat hippocampal slices.  Soc. Neuroscience, 26(2):1393 (#522.10).

Anderson, R.J., Hornung, B., Pittson, S., Monroe, F.A. and MacIver, M.B (2000)  Low concentrations of isoflurane block long term potentiation of hippocampal neuron synapses.  Anesthesiology 93(3A):A776.

Nishikawa, K. and MacIver, M.B.   (2000)  Membrane and synaptic actions of halothane on rat hippocampal pyramidal neurons and inhibitory interneurons. Anesthesiology 93(3A):A792.

MacIver, B., Harrison, N., Hemmings, H., Weight, F., Pearce, R.  (2000)  Anesthetic Actions at GABA and Glutamate Synapses.  Winter Conference on Brain  Research, 33:60.