Recent Abstracts:
Eric Lichtinger Velasco, Vytas Dargis-Robinson, B.S. and Bruce
MacIver (2010) Increased GABA-B receptor inhibition contributes
to isoflurane-induced depression of synapses. Soc. Neuroscience, 36
Bruce
MacIver, Youngjun Na and Vytas Dargis-Robinson, B.S. (2010)
GABA-B receptors located on CA1 dendrites appear to contribute
most to propofol-induced depression. Anesthesiology, 104
Bruce MacIver, Daniel Butler, Joshua Khani, Lisa
Rotenstein, Gily Raz, Eric Lichtinger Velasco, Vytas
Dargis-Robinson and Rona Giffard (2010) Removal of Calcium
Significantly Enhances Ischemic Insult Recovery in Rat Hippocampal
Brain Slices. Anesthesiology, 104
Bruce MacIver, Eric Lichtinger Velasco and Vytas Dargis-Robinson
(2010) Isoflurane depresses Synaptic Trasnsmission by Enhancing GABA-B
Receptor-Mediated Inhibition. Anesthesiology, 104
MacIver,
M.B., Jaffe, R.A. and Brock-Utne, J.G. (2010) Subthalamic neurons
recorded in humans exhibit agent selective responses to sedatives.
Winter Conference on Brain Research, 43.
Bruce MacIver, M.Sc., Ph.D. and Vytas Dargis-Robinson, B.S. (2009)
GABA-A fast synapses contribute the vast majority to propofol-induced
depression of CA1 neurons. Anesthesiology, 103
Vytas Dargis-Robinson, B.S. and Bruce MacIver, M.Sc., Ph.D. (2009)
GABA-B-mediated Inhibition Contributes to Propofol-Induced Depression
of Hippocampal Responses. Anesthesiology, 103
Bruce
MacIver, M.Sc., Ph.D., John Brock-Utne, M.D., Ph.D. and
Richard Jaffe, M.D., Ph.D. (2009) Subthalamic neurons recorded in
humans are differentially altered by propofol and remifentanil.
Anesthesiology, 103
Bruce MacIver, M.Sc., Ph.D. and Steve Towers, Ph.D. (2009) Using
isoflurane to probe dynamic properties of hippocampal gamma frequency
EEG activity. Anesthesiology, 103
Rotenstein, R., Giffard, R.G. and MacIver, M.B. (2009) Elevated
potassium associated with ischemia produces neuronal damage independent
of calcium influx into hippocampal CA1 cells. Winter Conference on
Brain Research, 42.
Towers, S.K and MacIver, M.B. (2008) Longer duration of inhibition in
brain slices that generate gamma oscillations. Anesthesiology, 101.
Dargis-Robinson, V. and MacIver, M.B. (2008) Comparing the
effectiveness and time course of several forms of synaptic inhibition.
Anesthesiology, 101.
MacIver, M.B., Brock-Utne, J.G. and Jaffe, R.A. (2008) Multiple actions
produced by propofol on subthalamic neurons recorded from humans. Soc.
Neuroscience, 34.
Towers, S.K. and MacIver, M.B. (2008) Gamma oscillations and longer
duration of paired pulse inhibition in horizontal versus coronal
hippocampal slices. Soc. Neuroscience, 34.
Dargis-Robinson, V. and MacIver, M.B. (2008) We know which is faster,
but which is stronger? Comparing GABA-A fast and GABA-A slow inhibition.
MacIver,
M.B. (2008) Abused Inhalants May Interfere wth Learning by Disrupting
Hippocampal Inhibitory Circuit Function. Winter
Conference on Brain Research, 41.
MacIver, M.B. (2007) Abused inhalant disruption of hippocampal circuit
function. Soc. Neuroscience, 33.
Sceniak, M.P. and MacIver, M.B. (2007) GABAa slow synaptic responses in
rat visual cortex. Soc. Neuroscience, 33.
Bieda, M, Su, H. and MacIver, M.B. (2007) Tonic and synaptic GABA-A
receptors exhibit differential sensitivities to volatile vs IV
anesthetics. Soc.
Neuroscience, 33.
Jaffe, R.A., Brock-Utne, J.G. and MacIver, M.B. (2007) Propofol
produces sedation for human DBS electrode implants without altering
subthalamic neuron electrophysiology. Soc. Neuroscience, 33.
Winegar, B.D. and MacIver, M.B. (2007) Propofol Actions on Spontaneous
Firing of Subthalamic Nucleus Neurons Soc. Neuroscience, 33.
MacIver, M.B.
(2007) EEG signals and IPSCs associated with
unconsciousness: Timing is everything. Winter
Conference on Brain Research, 40.
MacIver, M.B.
and J.G. Brock-Utne (2006) Comparison of
propofol effects
on human subthalamic vs thalamic neuron electrophysiology in
vivo. Anesthesiology, 99.
Henry Su, Mark
C. Bieda and M. Bruce MacIver (2006) Anesthetics
discriminate between tonic and synaptic GABA-A receptors on CA1
pyramidal neurons. Anesthesiology, 99.
Bruce D. Winegar
and M. Bruce MacIver (2006) Propofol prolongs
interspike intervals in rat subthalamic nucleus neurons in brain
slices. Anesthesiology, 99.
Michael P.
Sceniak and M. Bruce MacIver (2006) Slow GABAA synaptic
transmission in the rat visual cortex. Soc. Neuroscience, 32.
MacIver, M.B.
(2006) Abused inhalants target specific subtypes of
inhibitory nerve terminals on CA1 neurons. Soc. Neuroscience, 32.
Winegar, B.D.
and M.B. MacIver (2006) propofol depresses spike firing
in dopamine-sensitive rat subthalamic neurons. Soc. Neuroscience,
32.
Sceniak, M. and
MacIver, M.B. (2005) Urethane Anesthesia: A Novel and
Specific Mechanism of Action. Anesthesiology, 98.
Winegar, B. and
MacIver, M.B. (2005) Isoflurane Depression of
Hippocampal Synapse Glutamate Release Does Not Involve Sodium Channel
Block. Anesthesiology. 98.
Patricia A.
Turnquist and M. Bruce MacIver (2005) Anesthetic block of
LTP involves depression of NMDA EPSPs and enhanced GABA inhibition.
Soc. Neuroscience, 31.
Bruce D. Winegar
and Bruce M. MacIver (2005) Fiber volleys at
hippocampal CA1 glutamate nerve terminals are insensitive to clinical
concentrations of isoflurane. Soc. Neuroscience, 31.
MacIver, M.B.
(2004) Isoflurane depresses NMDA-mediated EPSPs at
concentrations that block LTP and learning in rats.
Soc Neuroscience
30:854.6
MacIver, M.B.
(2004) The Neurobiology of Consciousness. Winter
Conference on Brain Research, 37; 111.
Choi, D.,
Turnquist, P.A., McDonald, M.A. and MacIver, M.B. (2003)
Effects of Toluene on Hippocampal Synaptic Responses, Soc.
Neuroscience, 29; 10.7.
Turnquist, P.A.,
Choi, D.S. and MacIver, M.B. (2003) Toluene Effects on
Glutamate-Mediated Synaptic Responses. Anesthesiology, 97.
McDonald, M.A.,
Turnquist, P.A., Springer, J.D. and MacIver, M.B.
(2003) Ischemia-induced Potassium Ion Effects on Excitatory Synaptic
transmission. Anesthesiology, 97.
McDonald, M.A.,
Turnquist, P.A. and MacIver, M.B. (2003) Comparison of
Halothane and Toluene Actions at GABA Synapses. Anesthesiology,
97.
McDonald, M.A.
and MacIver, M.B. (2003) Isoflurane Actions on
Noradrenergic Inhibition of CA 1 Pyramidal Neurons.
Anesthesiology, 97.
MacIver M.B.
(2003) Comparison of IV and Inhalational Anesthetic
Actions at GABA synapses. Winter Conference on Brain Research,
35, 55.
Cheung, K. H-T
and MacIver, M.B. (2002) Isoflurane-Induced
Depression of Synaptic LTP does not Involve Post-NMDA Receptor Mediated
Mechanisms. Anesthesiology, 96: A815.
McDonald, M.A.,
Rastegar, J.C., Turnquist, P.A., and MacIver, M.B.
(2002) Ischemic Shock and High Potassium-Induced Depression of
Synaptic Transmission. Anesthesiology, 96: A718.
Turnquist, P.A.,
Bieda, M.C., Pittson, S., and MacIver, M.B.
(2002) Slow Diffusion Into Brain Slices Decreases the Apparent
Potency of an Anesthetic. Anesthesiology, 96: A790.
Bieda, M.C. and
MacIver, M.B. (2001) Propofol primarily targets
GABA-gated
chloride channels in hippocampal neurons. Anesthesiology
(accepted).
Bieda, M.C. and
MacIver, M.B. (2001) Propofol actions on
hippocampal
CA 1 inhibitory interneurons. Soc. Neuroscience (accepted)
Anderson, R.J.,
Hornung, B., Pittson, S., Monroe, F.A. and
MacIver,
M.B (2000) Isoflurane blocks LTP of hippocampal CA1 neurons at
concentrations
that block recall during anesthesia. Soc. Neuroscience,
26(1):1077
(#405.7).
Nishikawa, K. and
MacIver, M.B. (2000) Halothane produces
disinhibition
by depressing inhibitory interneurons in rat hippocampal slices.
Soc. Neuroscience, 26(2):1393 (#522.10).
Anderson, R.J.,
Hornung, B., Pittson, S., Monroe, F.A. and
MacIver,
M.B (2000) Low concentrations of isoflurane block long term
potentiation
of hippocampal neuron synapses. Anesthesiology 93(3A):A776.
Nishikawa, K. and
MacIver, M.B. (2000) Membrane
and
synaptic actions of halothane on rat hippocampal pyramidal neurons and
inhibitory interneurons. Anesthesiology 93(3A):A792.
MacIver, B.,
Harrison, N., Hemmings, H., Weight, F., Pearce,
R.
(2000) Anesthetic Actions at GABA and Glutamate Synapses.
Winter
Conference on Brain Research, 33:60.