Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands.
Submitted by Anonymous on Mon, 06/29/2015 - 02:35
Title | Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Sigal M, Rothenberg ME, Logan CY, Lee JY, Honaker RW, Cooper RL, Passarelli B, Camorlinga M, Bouley DM, Alvarez G, Nusse R, Torres J, Amieva MR |
Journal | Gastroenterology |
Volume | 148 |
Issue | 7 |
Pagination | 1392-1404.e21 |
Date Published | 2015 Jun |
ISSN | 0016-5085 |
Abstract | Helicobacter pylori infection is the main risk factor for gastric cancer. We characterized the interactions of H pylori with gastric epithelial progenitor and stem cells in humans and mice and investigated how these interactions contribute to H pylori-induced pathology. |
URL | http://linkinghub.elsevier.com/retrieve/pii/S0016-5085(15)00271-1 |
DOI | 10.1053/j.gastro.2015.02.049 |
Short Title | Gastroenterology |