Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands.

TitleHelicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands.
Publication TypeJournal Article
Year of Publication2015
AuthorsSigal M, Rothenberg ME, Logan CY, Lee JY, Honaker RW, Cooper RL, Passarelli B, Camorlinga M, Bouley DM, Alvarez G, Nusse R, Torres J, Amieva MR
JournalGastroenterology
Volume148
Issue7
Pagination1392-1404.e21
Date Published2015 Jun
ISSN0016-5085
AbstractHelicobacter pylori infection is the main risk factor for gastric cancer. We characterized the interactions of H pylori with gastric epithelial progenitor and stem cells in humans and mice and investigated how these interactions contribute to H pylori-induced pathology.
URLhttp://linkinghub.elsevier.com/retrieve/pii/S0016-5085(15)00271-1
DOI10.1053/j.gastro.2015.02.049
Short TitleGastroenterology