Publications

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2001
Wilson SI, Rydstrom A, Trimborn T, et al. "The status of Wnt signalling regulates neural and epidermal fates in the chick embryo." Nature. 2001;411:325-330. Abstract
2002
Willert J, Epping M, Pollack JR, Brown PO, Nusse R. "A transcriptional response to Wnt protein in human embryonic carcinoma cells." BMC Dev Biol. 2002;2:8. Abstract
Cadigan KM, Jou AD, Nusse R. "Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless." Development. 2002;129:3393-3402. Abstract
Penton A, Wodarz A, Nusse R. "A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin." Genetics. 2002;161:747-762. Abstract
Kozopas KM, Nusse R. "Direct flight muscles in Drosophila develop from cells with characteristics of founders and depend on DWnt-2 for their correct patterning." Dev Biol. 2002;243:312-325. Abstract
Rulifson EJ, Kim SK, Nusse R. "Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes." Science. 2002;296:1118-1120. Abstract
Yamazaki H, Nusse R. "Identification of DCAP, a drosophila homolog of a glucose transport regulatory complex." Mech Dev. 2002;119:115-119. Abstract
Wu C-hwa, Nusse R. "Ligand receptor interactions in the Wnt signaling pathway in Drosophila." J Biol Chem. 2002;277:41762-41769. Abstract
Povelones M, Nusse R. "Wnt signalling sees spots." Nat Cell Biol. 2002;4:E249-50.
Karger B, Nusse R, Bajanowski T. "Backspatter on the firearm and hand in experimental close-range gunshots to the head." Am J Forensic Med Pathol. 2002;23:211-213. Abstract
2003
Reya T, Duncan AW, Ailles L, et al. "A role for Wnt signalling in self-renewal of haematopoietic stem cells." Nature. 2003;423:409-414. Abstract
Willert K, Brown JD, Danenberg E, et al. "Wnt proteins are lipid-modified and can act as stem cell growth factors." Nature. 2003;423:448-452. Abstract
Nusse R. "Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface." Development. 2003;130:5297-5305. Abstract
Chen W, ten Berge D, Brown J, et al. "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4." Science. 2003;301:1391-1394. Abstract
2004
Logan CY, Nusse R. "The Wnt signaling pathway in development and disease." Annu Rev Cell Dev Biol. 2004;20:781-810. Abstract
Groth AC, Fish M, Nusse R, Calos MP. "Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31." Genetics. 2004;166:1775-1782. Abstract
Derksen PWB, Tjin E, Meijer HP, et al. "Illegitimate WNT signaling promotes proliferation of multiple myeloma cells." Proc Natl Acad Sci U S A. 2004;101:6122-6127. Abstract
Marino S, Romelfanger C, Yokota Y, Nusse R. "Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse." BMC Cancer. 2004;4:91. Abstract
Verras M, Brown J, Li X, Nusse R, Sun Z. "Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells." Cancer Res. 2004;64:8860-8866. Abstract
Kuhnert F, Davis CR, Wang H-T, et al. "Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1." Proc Natl Acad Sci U S A. 2004;101:266-271. Abstract
Nelson JW, Nusse R. "Convergence of Wnt, beta-catenin, and cadherin pathways." Science. 2004;303:1483-1487. Abstract
Galli LM, Willert K, Nusse R, et al. "A proliferative role for Wnt-3a in chick somites." Dev Biol. 2004;269:489-504. Abstract
Johnson ML, Harnish K, Nusse R, Van Hul W. "LRP5 and Wnt signaling: a union made for bone." J Bone Miner Res. 2004;19:1749-1757.
2005
Kon C, Cadigan KM, da Silva SL, Nusse R. "Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila." Genetics. 2005;169:2087-2100. Abstract
Nusse R. "Cell biology: relays at the membrane." Nature. 2005;438:747-749.