Publications

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Nelson JW, Nusse R. "Convergence of Wnt, beta-catenin, and cadherin pathways." Science. 2004;303:1483-1487. Abstract
Noordermeer J, Klingensmith J, Nusse R. "Differential requirements for segment polarity genes in wingless signaling." Mech Dev. 1995;51:145-155. Abstract
Noordermeer J, Klingensmith J, Perrimon N, Nusse R. "dishevelled and armadillo act in the wingless signalling pathway in Drosophila." Nature. 1994;367:80-83. Abstract
Noordermeer J, Johnston P, Rijsewijk F, Nusse R, Lawrence PA. "The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo." Development. 1992;116:711-719. Abstract
Nusse R. "Patching up Hedgehog." Nature. 1996;384:119-120.
Nusse R, Janssen H, de Vries L, Michalides R. "Analysis of secondary modifications of mouse mammary tumor virus proteins by two-dimensional gel electrophoresis." J Virol. 1980;35:340-348. Abstract
Nusse R. "WNT targets. Repression and activation." Trends Genet. 1999;15:1-3. Abstract
Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. "Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15." Nature. 1984;307:131-136. Abstract
Nusse R. "An ancient cluster of Wnt paralogues." Trends Genet. 2001;17:443.
Nusse R. "The int genes in mammary tumorigenesis and in normal development." Trends Genet. 1988;4:291-295.
Nusse R. "Wnt signaling in disease and in development." Cell Res. 2005;15:28-32. Abstract
Nusse R. "Insertional mutagenesis in mouse mammary tumorigenesis." Curr Top Microbiol Immunol. 1991;171:43-65.
Nusse R, Clevers H. "Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities." Cell. 2017;169(6):985-999. Abstract
Nusse R. "Wnt signaling and stem cell control." Cell Res. 2008;18:523-527. Abstract
Nusse R. "The Wnt gene family in tumorigenesis and in normal development." J Steroid Biochem Mol Biol. 1992;43:9-12. Abstract
Nusse R. "Wnt signaling." Cold Spring Harbor perspectives in biology. 2012;4(5).
Nusse R, Michalides R, Boot LM, Ropcke G. "Quantification of mouse mammary tumor virus structural proteins in hormone-induced mammary tumors of low mammary tumor mouse strains." Int J Cancer. 1980;25:377-383. Abstract
Nusse R. "A versatile transcriptional effector of Wingless signaling." Cell. 1997;89:321-323.
Nusse R, Varmus HE. "Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome." Cell. 1982;31:99-109. Abstract
Nusse R. "Developmental biology. Making head or tail of Dickkopf." Nature. 2001;411:255-256.
Nusse R. "The activation of cellular oncogenes by proviral insertion in murine mammary cancer." Cancer Treat Res. 1988;40:283-306.
Nusse R, Theunissen H, Wagenaar E, et al. "The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus." Mol Cell Biol. 1990;10:4170-4179. Abstract
Nusse R. "Cancer. Converging on beta-catenin in Wilms tumor." Science. 2007;316:988-989.
Nusse R, Varmus HE. "Wnt genes." Cell. 1992;69:1073-1087.
Nusse R, Varmus H. "Three decades of Wnts: a personal perspective on how a scientific field developed." The EMBO journal. 2012;31(12):2670-84. Abstract