Publications

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Nelson JW, Nusse R. "Convergence of Wnt, beta-catenin, and cadherin pathways." Science. 2004;303:1483-1487. Abstract
Noordermeer J, Klingensmith J, Nusse R. "Differential requirements for segment polarity genes in wingless signaling." Mech Dev. 1995;51:145-155. Abstract
Noordermeer J, Klingensmith J, Perrimon N, Nusse R. "dishevelled and armadillo act in the wingless signalling pathway in Drosophila." Nature. 1994;367:80-83. Abstract
Noordermeer J, Johnston P, Rijsewijk F, Nusse R, Lawrence PA. "The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo." Development. 1992;116:711-719. Abstract
Nusse R. "Insertional mutagenesis in mouse mammary tumorigenesis." Curr Top Microbiol Immunol. 1991;171:43-65.
Nusse R, Clevers H. "Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities." Cell. 2017;169(6):985-999. Abstract
Nusse R. "Wnt signaling in disease and in development." Cell Res. 2005;15:28-32. Abstract
Nusse R. "The Wnt gene family in tumorigenesis and in normal development." J Steroid Biochem Mol Biol. 1992;43:9-12. Abstract
Nusse R. "Wnt signaling." Cold Spring Harbor perspectives in biology. 2012;4(5).
Nusse R. "Wnt signaling and stem cell control." Cell Res. 2008;18:523-527. Abstract
Nusse R, Michalides R, Boot LM, Ropcke G. "Quantification of mouse mammary tumor virus structural proteins in hormone-induced mammary tumors of low mammary tumor mouse strains." Int J Cancer. 1980;25:377-383. Abstract
Nusse R. "A versatile transcriptional effector of Wingless signaling." Cell. 1997;89:321-323.
Nusse R, Varmus HE. "Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome." Cell. 1982;31:99-109. Abstract
Nusse R. "Developmental biology. Making head or tail of Dickkopf." Nature. 2001;411:255-256.
Nusse R. "The activation of cellular oncogenes by proviral insertion in murine mammary cancer." Cancer Treat Res. 1988;40:283-306.
Nusse R, Theunissen H, Wagenaar E, et al. "The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus." Mol Cell Biol. 1990;10:4170-4179. Abstract
Nusse R, Varmus HE. "Wnt genes." Cell. 1992;69:1073-1087.
Nusse R, Varmus H. "Three decades of Wnts: a personal perspective on how a scientific field developed." The EMBO journal. 2012;31(12):2670-84. Abstract
Nusse R. "Cancer. Converging on beta-catenin in Wilms tumor." Science. 2007;316:988-989.
Nusse R, van der Ploeg L, van Duijn L, Michalides R, Hilgers J. "Impaired maturation of mouse mammary tumor virus precursor polypeptides in lymphoid leukemia cells, producing intracytoplasmic A particles and no extracellular B-type virions." J Virol. 1979;32:251-258. Abstract
Nusse R, Samos CH, Brink M, et al. "Cell culture and whole animal approaches to understanding signaling by Wnt proteins in Drosophila." Cold Spring Harb Symp Quant Biol. 1997;62:185-190.
Nusse R, de Moes J, Hilkens J, van Nie R. "Localization of a gene for expression of mouse mammary tumor virus antigens in the GR/Mtv-2- mouse strain." J Exp Med. 1980;152:712-719. Abstract
Nusse R, Rulifson E, Fish M, et al. "Interactions between wingless and frizzled molecules in Drosophila." Ernst Schering Res Found Workshop. 2000:1-11.
Nusse R, van Ooyen A, Rijsewijk F, van Lohuizen M, Schuuring E, van't Veer L. "Retroviral insertional mutagenesis in murine mammary cancer." Proc R Soc Lond B Biol Sci. 1985;226:3-13. Abstract
Nusse R. "Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface." Development. 2003;130:5297-5305. Abstract