Publications

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2021
Russell JP, Lim X, Santambrogio A, et al. "Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells." eLife. 2021;10. Abstract
2020
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
2016
Lim X, Tan SH, Yu KL, Lim SB, Nusse R. "Axin2 marks quiescent hair follicle bulge stem cells that are maintained by autocrine Wnt/β-catenin signaling." Proceedings of the National Academy of Sciences of the United States of America. 2016;113(11):E1498-505. Abstract
2015
Lee SH, Johnson DT, Luong R, et al. "Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration." Stem cells (Dayton, Ohio). 2015;33(11):3356-67. Abstract
Guenther CA, Wang Z, Li E, et al. "A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury." Bone. 2015;77:31-41. Abstract
2013
Ardehali R, Ali SR, Inlay MA, et al. "Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(9):3405-10. Abstract
Lim X, Tan SH, Koh WL, et al. "Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling." Science (New York, N.Y.). 2013;342(6163):1226-30. Abstract
Green JL, La J, Yum KW, et al. "Paracrine Wnt signaling both promotes and inhibits human breast tumor growth." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(17):6991-6. Abstract
2011
Fancy SP, Harrington EP, Yuen TJ, et al. "Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination." Nature neuroscience. 2011;14(8):1009-16. Abstract
2004
Galli LM, Willert K, Nusse R, et al. "A proliferative role for Wnt-3a in chick somites." Dev Biol. 2004;269:489-504. Abstract
Kuhnert F, Davis CR, Wang H-T, et al. "Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1." Proc Natl Acad Sci U S A. 2004;101:266-271. Abstract
Marino S, Romelfanger C, Yokota Y, Nusse R. "Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse." BMC Cancer. 2004;4:91. Abstract
2003
Willert K, Brown JD, Danenberg E, et al. "Wnt proteins are lipid-modified and can act as stem cell growth factors." Nature. 2003;423:448-452. Abstract
2002
Yamazaki H, Nusse R. "Identification of DCAP, a drosophila homolog of a glucose transport regulatory complex." Mech Dev. 2002;119:115-119. Abstract
1995
Yanagawa S, van Leeuwen F, Wodarz A, Klingensmith J, Nusse R. "The dishevelled protein is modified by wingless signaling in Drosophila." Genes Dev. 1995;9:1087-1097. Abstract
1990
van Leeuwen F, Van de Vijver MJ, Lomans J, et al. "Mutation of the human neu protein facilitates down-modulation by monoclonal antibodies." Oncogene. 1990;5:497-503. Abstract