%0 Journal Article %J Mol Cell Biol %D 1984 %T Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis. %A van 't Veer, L J %A van Kessel, A G %A van Heerikhuizen, H %A van Ooyen, A %A Nusse, R %P 2532–2534 %V 4 %X Viral mammary tumorigenesis in mice is frequently initiated by proviral activation of a highly conserved cellular gene called int-1. We have cloned the human homolog of this putative mammary oncogene and compared its structure to that of the mouse gene by heteroduplex analysis. The human int-1 gene was localized on chromosome 12 by use of somatic cell hybrids. %8 Nov