Publications

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2008
Gordon MD, Ayres JS, Schneider DS, Nusse R. "Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin." PLoS Pathog. 2008;4:e1000111. Abstract
Chen W-S, Antic D, Matis M, et al. "Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling." Cell. 2008;133:1093-1105. Abstract
Ching W, Hang HC, Nusse R. "Lipid-independent secretion of a Drosophila Wnt protein." J Biol Chem. 2008;283:17092-17098. Abstract
Nusse R. "Wnt signaling and stem cell control." Cell Res. 2008;18:523-527. Abstract
ten Berge D, Koole W, Fuerer C, Fish M, Eroglu E, Nusse R. "Wnt signaling mediates self-organization and axis formation in embryoid bodies." Cell Stem Cell. 2008;3:508-518. Abstract
Kalani YMS, Cheshier SH, Cord BJ, et al. "Wnt-mediated self-renewal of neural stem/progenitor cells." Proc Natl Acad Sci U S A. 2008;105:16970-16975. Abstract
Leucht P, Minear S, ten Berge D, Nusse R, Helms JA. "Translating insights from development into regenerative medicine: the function of Wnts in bone biology." Semin Cell Dev Biol. 2008;19:434-443. Abstract
ten Berge D, Brugmann SA, Helms JA, Nusse R. "Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development." Development. 2008;135:3247-3257. Abstract
Groen RWJ, Oud MECM, Schilder-Tol EJM, et al. "Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies." Cancer Res. 2008;68:6969-6977. Abstract
2009
Wright TM, Brannon AR, Gordan JD, et al. "Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma." Oncogene. 2009;28:2513-2523. Abstract
Park J-I, Venteicher AS, Hong JY, et al. "Telomerase modulates Wnt signalling by association with target gene chromatin." Nature. 2009;460:66-72. Abstract
Mikels A, Minami Y, Nusse R. "Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling." J Biol Chem. 2009;284:30167-30176. Abstract
van Amerongen R, Nusse R. "Towards an integrated view of Wnt signaling in development." Development. 2009;136:3205-3214. Abstract
2010
Fuerer C, Nusse R. "Lentiviral vectors to probe and manipulate the Wnt signaling pathway." PLoS One. 2010;5:e9370. Abstract
Zeng YA, Nusse R. "Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture." Cell Stem Cell. 2010;6(6):568-77. Abstract
Minear S, Leucht P, Jiang J, et al. "Wnt proteins promote bone regeneration." Sci Transl Med. 2010;2:29ra30. Abstract
Fuerer C, Habib SJ, Nusse R. "A study on the interactions between heparan sulfate proteoglycans and Wnt proteins." Dev Dyn. 2010;239:184-190. Abstract
Zeng YA, Nusse R. "Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture." Cell Stem Cell. 2010;6:568-577. Abstract
2011
ten Berge D, Kurek D, Blauwkamp T, et al. "Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells." Nature cell biology. 2011;13(9):1070-5. Abstract
Fancy SP, Harrington EP, Yuen TJ, et al. "Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination." Nature neuroscience. 2011;14(8):1009-16. Abstract
Bowman A, Nusse R. "Location, location, location: FoxM1 mediates β-catenin nuclear translocation and promotes glioma tumorigenesis." Cancer cell. 2011;20(4):415-6. Abstract
2012
McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. "A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration." PloS one. 2012;6(11):e26993. Abstract
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. "Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility." Proceedings of the National Academy of Sciences of the United States of America. 2012;109(2):370-7. Abstract
Edris B, Espinosa I, Mühlenberg T, et al. "ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour." The Journal of pathology. 2012;227(2):223-33. Abstract
Clevers H, Nusse R. "Wnt/β-catenin signaling and disease." Cell. 2012;149(6):1192-205. Abstract