Publications

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Journal Article
Rulifson IC, Karnik SK, Heiser PW, et al. "Wnt signaling regulates pancreatic beta cell proliferation." Proc Natl Acad Sci U S A. 2007;104:6247-6252. Abstract
Nusse R. "Wnt signaling." Cold Spring Harbor perspectives in biology. 2012;4(5).
Cadigan KM, Nusse R. "Wnt signaling: a common theme in animal development." Genes Dev. 1997;11:3286-3305.
Gordon MD, Nusse R. "Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors." J Biol Chem. 2006;281:22429-22433.
Fuerer C, Nusse R, ten Berge D. "Wnt signalling in development and disease. Max Delbruck Center for Molecular Medicine meeting on Wnt signaling in Development and Disease." EMBO Rep. 2008;9:134-138.
Povelones M, Nusse R. "Wnt signalling sees spots." Nat Cell Biol. 2002;4:E249-50.
Wiese KE, Nusse R, van Amerongen R. "Wnt signalling: conquering complexity." Development (Cambridge, England). 2018;145(12). Abstract
Nusse R. "WNT targets. Repression and activation." Trends Genet. 1999;15:1-3. Abstract
Nusse R, Theunissen H, Wagenaar E, et al. "The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus." Mol Cell Biol. 1990;10:4170-4179. Abstract
Roelink H, Wagenaar E, Lopes da Silva S, Nusse R. "Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain." Proc Natl Acad Sci U S A. 1990;87:4519-4523. Abstract
Willert K, Shibamoto S, Nusse R. "Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex." Genes Dev. 1999;13:1768-1773. Abstract
Kalani YMS, Cheshier SH, Cord BJ, et al. "Wnt-mediated self-renewal of neural stem/progenitor cells." Proc Natl Acad Sci U S A. 2008;105:16970-16975. Abstract
Hu M, Kurobe M, Jeong YJ, et al. "Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells." Gastroenterology. 2007;133:1579-1591. Abstract
Clevers H, Nusse R. "Wnt/β-catenin signaling and disease." Cell. 2012;149(6):1192-205. Abstract
Xing L, Anbarchian T, Tsai JM, Plant GW, Nusse R. "Wnt/β-catenin signaling regulates ependymal cell development and adult homeostasis." Proceedings of the National Academy of Sciences of the United States of America. 2018;115(26):E5954-E5962. Abstract
Nusse R, Clevers H. "Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities." Cell. 2017;169(6):985-999. Abstract
Lee SH, Johnson DT, Luong R, et al. "Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration." Stem cells (Dayton, Ohio). 2015;33(11):3356-67. Abstract
Marino S, Romelfanger C, Yokota Y, Nusse R. "Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse." BMC Cancer. 2004;4:91. Abstract
Verras M, Brown J, Li X, Nusse R, Sun Z. "Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells." Cancer Res. 2004;64:8860-8866. Abstract
van Amerongen R, Fuerer C, Mizutani M, Nusse R. "Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development." Developmental biology. 2012;369(1):101-14. Abstract
Gordon MD, Dionne MS, Schneider DS, Nusse R. "WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity." Nature. 2005;437:746-749. Abstract
Nusse R. "Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface." Development. 2003;130:5297-5305. Abstract
Mikels AJ, Nusse R. "Wnts as ligands: processing, secretion and reception." Oncogene. 2006;25:7461-7468. Abstract
Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R. "Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation." Proceedings of the National Academy of Sciences of the United States of America. 2014;111(49):E5262-71. Abstract
Basham KJ, Rodriguez S, Turcu AF, et al. "A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis." Genes & development. 2019;33(3-4):209-220. Abstract