Simon Lab Publications

Ma, D., Yang, C-.H. , McNeill, H., Simon, M.A., and Axelrod, J.D. (2003). Fidelity in planar cell polarity signaling. Nature 421, 543-7. PDF

Yang, C. H., Axelrod, J. D., and Simon, M. A. (2002). Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108, 675-88. PDF

Smith, R. K., Carroll, P. M., Allard, J. D., and Simon, M. A. (2002). MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila receptor tyrosine kinase signaling. Development 129, 71-82. PDF

Simon, M. A. (2000). Receptor tyrosine kinases: specific outcomes from general signals. Cell 103, 13-5. PDF

Herbst, R., Zhang, X., Qin, J., and Simon, M. A. (1999). Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase. EMBO Journal 18, 6950-61. PDF

Yang, C. H., Simon, M. A., and McNeill, H. (1999). mirror controls planar polarity and equator formation through repression of fringe expression and through control of cell affinities. Development 126, 5857-66. PDF

Guarnieri, D. J., Dodson, G. S., and Simon, M. A. (1998). SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth. Molecular Cell 1, 831-40. PDF

Dodson, G. S., Guarnieri, D. J., and Simon, M. A. (1998). Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis. Development 125, 2883-92. PDF

Le, N., and Simon, M. A. (1998). Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase. Molecular Cell Biology 18, 4844-54. PDF

Allard, J. D., Herbst, R., Carroll, P. M., and Simon, M. A. (1998). Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew. Journal of Biological Chemistry 273, 13129-35. PDF

McNeill, H., Yang, C. H., Brodsky, M., Ungos, J., and Simon, M. A. (1997). mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. Genes and Development 11, 1073-82. Summary

Herbst, R., Carroll, P. M., Allard, J. D., Schilling, J., Raabe, T., and Simon, M. A. (1996). Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. Cell 85, 899-909. PDF

Cooper, J. A., Simon, M. A., and Kussick, S. J. (1996). Signaling by ectopically expressed Drosophila Src64 requires the protein-tyrosine phosphatase corkscrew and the adapter downstream of receptor kinases. Cellular Growth and Differentiation 7, 1435-41. Summary

Allard, J. D., Chang, H. C., Herbst, R., McNeill, H., and Simon, M. A. (1996). The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf. Development 122, 1137-46. PDF

Simon, M. A. (1994). Signal transduction during the development of the Drosophila R7 photoreceptor. Developmental Biology 166, 431-42.

Simon, M. A., Dodson, G. S., and Rubin, G. M. (1993). An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 73, 169-77. Summary

Earlier publications

Fortini, M. E., Simon, M. A., and Rubin, G. M. (1992). Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation, Nature 355, 559-61. Summary

Bowtell, D., Fu, P., Simon, M., and Senior, P. (1992). Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras, PNAS 89, 6511-5. Summary

Simon, M. A., Bowtell, D. D., Dodson, G. S., Laverty, T. R., and Rubin, G. M. (1991). Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase, Cell 67, 701-16. Summary

Simon, M. A., Bowtell, D. D., and Rubin, G. M. (1989). Structure and activity of the sevenless protein: a protein tyrosine kinase receptor required for photoreceptor development in Drosophila, PNAS 86, 8333-7. Summary

Bowtell, D. D., Simon, M. A., and Rubin, G. M. (1989). Ommatidia in the developing Drosophila eye require and can respond to sevenless for only a restricted period, Cell 56, 931-6. Summary

Bowtell, D. D., Kimmel, B. E., Simon, M. A., and Rubin, G. M. (1989). Regulation of the complex pattern of sevenless expression in the developing Drosophila eye, PNAS 86, 6245-9. Summary

Bowtell, D. D., Simon, M. A., and Rubin, G. M. (1988). Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster, Genes and Development 2, 620-34. Summary

Simon, M. A., Drees, B., Kornberg, T., and Bishop, J. M. (1985). The nucleotide sequence and the tissue-specific expression of Drosophila c-src, Cell 42, 831-40. Summary

Kornberg, T., Siden, I., O'Farrell, P., and Simon, M. A. (1985) The engrailed locus of Drosophila: in situ localization of transcripts reveals compartment-specific expression, Cell 40, 45-53. Summary

Simon, M. A., Kornberg, T. B., and Bishop, J. M. (1983). Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila, Nature 302, 837-9. Summary

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