Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform.
Kidess E, Heirich K, Wiggin M, Vysotskaia V, Visser BC, Marziali A, Wiedenmann B, Norton JA, Lee M, Jeffrey SS, Poultsides GA. Oncotarget. 2014 Dec 10. PMID: 25575824 Link
High-throughput time-resolved FRET reveals Akt/PKB activation as a poor prognostic marker in breast cancer.
Veeriah S, Leboucher P, de Naurois J, Jethwa N, Nye E, Bunting T, Stone R, Stamp G, Calleja V, Jeffrey SS, Parker PJ, Larijani B. Cancer Res. 2014 Sep 15;74(18):4983-95. doi: 10.1158/0008-5472.CAN-13-3382. Epub 2014 Jun 26. PMID: 24970478 Link
Single cell mutational analysis of PIK3CA in circulating tumor cells and metastases in breast cancer reveals heterogeneity, discordance, and mutation persistence in cultured disseminated tumor cells from bone marrow.
Deng G, Krishnakumar S, Powell AA, Zhang H, Mindrinos MN, Telli ML, Davis RW, Jeffrey SS. BMC Cancer. 2014 Jun 19;14:456. doi: 10.1186/1471-2407-14-456. PMID: 24947048 Link
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition.
Zhang H, Cohen AL, Krishnakumar S, Wapnir IL, Veeriah S, Deng G, Coram MA, Piskun CM, Longacre TA, Herrler M, Frimannsson DO, Telli ML, Dirbas FM, Matin AC, Dairkee SH, Larijani B, Glinsky GV, Bild AH, Jeffrey SS. Breast Cancer Res. 2014 Apr 7;16(2):R36. doi: 10.1186/bcr3640. PMID: 24708766 Link
Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips.
Earhart CM, Hughes CE, Gaster RS, Ooi CC, Wilson RJ, Zhou LY, Humke EW, Xu L, Wong DJ, Willingham SB, Schwartz EJ, Weissman IL, Jeffrey SS, Neal JW, Rohatgi R, Wakelee HA, Wang SX. Lab Chip. 2014 Jan 7;14(1):78-88. doi: 10.1039/c3lc50580d. PMID: 23969419 Link
Impact of navigation on knowledge and attitudes about clinical trials among Chinese patients undergoing treatment for breast and gynecologic cancers.
Clair McClung E, Davis SW, Jeffrey SS, Kuo MC, Lee MM, Teng NN. J Immigr Minor Health. 2013 Aug 21. PMID: 23963874 Link
Circulating tumor cells versus tumor-derived cell-free DNA: rivals or partners in cancer care in the era of single-cell analysis?
Kidess E, Jeffrey SS. Genome Med. 2013 Aug 13;5(8):70. doi: 10.1186/gm474. eCollection 2013. PMID: 23953663 Link
Colorectal cancer diagnostics: biomarkers, cell-free DNA, circulating tumor cells and defining heterogeneous populations by single-cell analysis.
Kin C, Kidess E, Poultsides GA, Visser BC, Jeffrey SS. Expert Rev Mol Diagn. 2013 Jul;13(6):581-99. doi: 10.1586/14737159.2013.811896. PMID: 23895128 Link
Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress.
Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. PLoS One. 2013 Apr 30;8(4):e62758. doi: 10.1371/journal.pone.0062758. Print 2013. PMID: 23646141 Link
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines.
Powell AA, Talasaz AH, Zhang H, Coram MA, Reddy A, Deng G, Telli ML, Advani RH, Carlson RW, Mollick JA, Sheth S, Kurian AW, Ford JM, Stockdale FE, Quake SR, Pease RF, Mindrinos MN, Bhanot G, Dairkee SH, Davis RW, Jeffrey SS. PLoS One. 2012;7(5):e33788. doi: 10.1371/journal.pone.0033788. Epub 2012 May 7. PMID: 22586443 Link
Multiplex molecular analysis of CTCs.
Sieuwerts AM, Jeffrey SS. Recent Results Cancer Res. 2012;195:125-40. doi: 10.1007/978-3-642-28160-0_11. PMID: 22527500 Link
Adipose levels of polybrominated diphenyl ethers and risk of breast cancer.
Hurley S, Reynolds P, Goldberg D, Nelson DO, Jeffrey SS, Petreas M. Breast Cancer Res Treat. 2011 Sep;129(2):505-11. Epub 2011 Apr 6. PMID: 21468638 Link
A pharmacogenomic method for individualized prediction of drug sensitivity.
Cohen AL, Soldi R, Zhang H, Gustafson AM, Wilcox R, Welm BE, Chang JT, Johnson E, Spira A, Jeffrey SS, Bild AH. Mol Syst Biol. 2011 Jul 19;7:513. doi: 10.1038/msb.2011.47. PMID: 21772261 Link
Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells.
Luciani MG, Seok J, Sayeed A, Champion S, Goodson WH, Jeffrey SS, Xiao W, Mindrinos M, Davis RW, Dairkee SH. PLoS One. 2011;6(5):e20016. Epub 2011 May 19. PMID: 21625507 Link
Characterization of molecular subtypes of Korean breast cancer: an ethnically and clinically distinct population.
Han W, Nicolau M, Noh DY, Jeffrey SS. Int J Oncol. 2010 Jul;37(1):51-9. PMID: 20514396 Link
Stem cells in human breast cancer.
Oliveira LR, Jeffrey SS, Ribeiro-Silva A. Histol Histopathol. 2010 Mar;25(3):371-85. Review. PMID: 20054808 Link
Focal amplification and oncogene dependency of GAB2 in breast cancer.
Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR. Oncogene. 2010 Feb 4;29(5):774-9. Epub 2009 Nov 2. PMID: 19881546 Link
Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.
Ameri K, Luong R, Zhang H, Powell AA, Montgomery KD, Espinosa I, Bouley DM, Harris AL, Jeffrey SS. Br J Cancer. 2010 Feb 2;102(3):561-9. Epub 2010 Jan 5. PMID: 20051957 Link
Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device.
Talasaz AH, Powell AA, Huber DE, Berbee JG, Roh KH, Yu W, Xiao W, Davis MM, Pease RF, Mindrinos MN, Jeffrey SS, Davis RW. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3970-5. Epub 2009 Feb 20. PMID: 19234122 Link
CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer.
Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR. Mol Oncol. 2008 Dec;2(4):327-39. Epub 2008 Oct 2. PMID: 19383354 Link
DNA copy number alterations and expression of relevant genes in triple-negative breast cancer.
Han W, Jung EM, Cho J, Lee JW, Hwang KT, Yang SJ, Kang JJ, Bae JY, Jeon YK, Park IA, Nicolau M, Jeffrey SS, Noh DY. Genes Chromosomes Cancer. 2008 Jun;47(6):490-9. PMID: 18314908 Link
Cancer biomarker profiling with microRNAs.
Jeffrey SS. Nat Biotechnol. 2008 Apr;26(4):400-1. No abstract available. PMID: 18392022 Link
Basal carcinoma of the breast revisited: an old entity with new interpretations.
Korsching E, Jeffrey SS, Meinerz W, Decker T, Boecker W, Buerger H. J Clin Pathol. 2008 May;61(5):553-60. Epub 2008 Mar 6. Review. PMID: 18326009 Link
New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients.
Kohrt HE, Olshen RA, Bermas HR, Goodson WH, Wood DJ, Henry S, Rouse RV, Bailey L, Philben VJ, Dirbas FM, Dunn JJ, Johnson DL, Wapnir IL, Carlson RW, Stockdale FE, Hansen NM, Jeffrey SS; Bay Area SLN Study. BMC Cancer. 2008 Mar 4;8:66. PMID: 18315887 Link
Estrogen receptor-negative invasive breast cancer: imaging features of tumors with and without human epidermal growth factor receptor type 2 overexpression.
Wang Y, Ikeda DM, Narasimhan B, Longacre TA, Bleicher RJ, Pal S, Jackman RJ, Jeffrey SS. Radiology. 2008 Feb;246(2):367-75. Epub 2008 Jan 7. PMID: 18180338 Link
MRI-guided radiofrequency ablation of breast cancer: preliminary clinical experience.
van den Bosch M, Daniel B, Rieke V, Butts-Pauly K, Kermit E, Jeffrey S. J Magn Reson Imaging. 2008 Jan;27(1):204-8. PMID: 18050333 Link
RNA extraction from ten year old formalin-fixed paraffin-embedded breast cancer samples: a comparison of column purification and magnetic bead-based technologies.
Ribeiro-Silva A, Zhang H, Jeffrey SS. BMC Mol Biol. 2007 Dec 21;8:118. PMID: 18154675 Link
Oxidative stress pathways highlighted in tumor cell immortalization: association with breast cancer outcome.
Dairkee SH, Nicolau M, Sayeed A, Champion S, Ji Y, Moore DH, Yong B, Meng Z, Jeffrey SS. Oncogene. 2007 Sep 20;26(43):6269-79. PMID: 17471242 Link
Transcriptomic signatures in breast cancer.
Fu J, Jeffrey SS. Mol Biosyst. 2007 Jul;3(7):466-72. Epub 2007 Jun 5. Review. PMID: 17579771 Link
Disease-specific genomic analysis: identifying the signature of pathologic biology.
Nicolau M, Tibshirani R, Børresen-Dale AL, Jeffrey SS. Bioinformatics. 2007 Apr 15;23(8):957-65. Epub 2007 Feb 3. PMID: 17277331 Link
TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer.
Langerød A, Zhao H, Borgan Ø, Nesland JM, Bukholm IR, Ikdahl T, Kåresen R, Børresen-Dale AL, Jeffrey SS. Breast Cancer Res. 2007;9(3):R30. PMID: 17504517 Link
Discovery and validation of breast cancer subtypes.
Kapp AV, Jeffrey SS, Langerød A, Børresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R. BMC Genomics. 2006 Sep 11;7:231. Erratum in: BMC Genomics. 2007 Apr 13;8(1):101. PMID: 16965636 Link
Radiation-induced effects on gene expression: an in vivo study on breast cancer.
Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL. Radiother Oncol. 2006 Aug;80(2):230-5. Epub 2006 Aug 4. PMID: 16890317 Link
MRI-guided needle localization of suspicious breast lesions: results of a freehand technique.
van den Bosch MA, Daniel BL, Pal S, Nowels KW, Birdwell RL, Jeffrey SS, Ikeda DM. Eur Radiol. 2006 Aug;16(8):1811-7. Epub 2006 May 9. PMID: 16683117 Link
Lysyl oxidase is essential for hypoxia-induced metastasis.
Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. Nature. 2006 Apr 27;440(7088):1222-6. PMID: 16642001 Link
Cell trapping in activated micropores for functional analysis.
Talasaz AH, Powell AA, Stahl P, Ronaghi M, Jeffrey SS, Mindrinos M, Davis RW. Conf Proc IEEE Eng Med Biol Soc. 2006;1:1838-41. Review. PMID: 17945673 Link
A streamlined platform for high-content functional proteomics of primary human specimens.
Jessani N, Niessen S, Wei BQ, Nicolau M, Humphrey M, Ji Y, Han W, Noh DY, Yates JR 3rd, Jeffrey SS, Cravatt BF. Nat Methods. 2005 Sep;2(9):691-7. PMID: 16118640 Link
MRI features of mucosa-associated lymphoid tissue lymphoma in the breast.
Espinosa LA, Daniel BL, Jeffrey SS, Nowels KW, Ikeda DM. AJR Am J Roentgenol. 2005 Jul;185(1):199-202. No abstract available. PMID: 15972423 Link
Adipose levels of dioxins and risk of breast cancer.
Reynolds P, Hurley SE, Petreas M, Goldberg DE, Smith D, Gilliss D, Mahoney ME, Jeffrey SS. Cancer Causes Control. 2005 Jun;16(5):525-35. PMID: 15986107 Link
Genomics-based prognosis and therapeutic prediction in breast cancer.
Jeffrey SS, Lønning PE, Hillner BE. J Natl Compr Canc Netw. 2005 May;3(3):291-300. Review. PMID: 16002001 Link
Rates of reexcision for breast cancer after magnetic resonance imaging-guided bracket wire localization.
Wallace AM, Daniel BL, Jeffrey SS, Birdwell RL, Nowels KW, Dirbas FM, Schraedley-Desmond P, Ikeda DM. J Am Coll Surg. 2005 Apr;200(4):527-37. PMID: 15804466 Link
The evolution of accelerated, partial breast irradiation as a potential treatment option for women with newly diagnosed breast cancer considering breast conservation.
Dirbas FM, Jeffrey SS, Goffinet DR. Cancer Biother Radiopharm. 2004 Dec;19(6):673-705. Review. PMID: 15665616 Link
Magnetic resonance imaging of suspicious breast masses seen on one mammographic view.
Offodile RS, Daniel BL, Jeffrey SS, Wapnir I, Dirbas FM, Ikeda DM. Breast J. 2004 Sep-Oct;10(5):416-22. PMID: 15327495 Link
A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue.
Dairkee SH, Ji Y, Ben Y, Moore DH, Meng Z, Jeffrey SS. BMC Genomics. 2004 Jul 19;5(1):47. PMID: 15260889 Link
Different gene expression patterns in invasive lobular and ductal carcinomas of the breast.
Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS. Mol Biol Cell. 2004 Jun;15(6):2523-36. Epub 2004 Mar 19. PMID: 15034139 Link
Distribution of persistent, lipid-soluble chemicals in breast and abdominal adipose tissues: lessons learned from a breast cancer study.
Petreas M, Smith D, Hurley S, Jeffrey SS, Gilliss D, Reynolds P. Cancer Epidemiol Biomarkers Prev. 2004 Mar;13(3):416-24. PMID: 15006918 Link
Predictors of reexcision findings and recurrence after breast conservation.
Smitt MC, Nowels K, Carlson RW, Jeffrey SS. Int J Radiat Oncol Biol Phys. 2003 Nov 15;57(4):979-85. PMID: 14575828 Link
The diagnosis and management of pre-invasive breast disease: promise of new technologies in understanding pre-invasive breast lesions.
Jeffrey SS, Pollack JR. Breast Cancer Res. 2003;5(6):320-8. Epub 2003 Oct 9. Review. PMID: 14580250 Link
Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis.
Zhao H, Hastie T, Whitfield ML, Børresen-Dale AL, Jeffrey SS. BMC Genomics. 2002 Oct 30;3(1):31. PMID: 12445333 Link
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors.
Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12963-8. Epub 2002 Sep 24. PMID: 12297621 Link
MR imaging features of infiltrating lobular carcinoma of the breast: histopathologic correlation.
Qayyum A, Birdwell RL, Daniel BL, Nowels KW, Jeffrey SS, Agoston TA, Herfkens RJ. AJR Am J Roentgenol. 2002 May;178(5):1227-32. PMID: 11959737 Link
Expression array technology in the diagnosis and treatment of breast cancer.
Jeffrey SS, Fero MJ, Børresen-Dale AL, Botstein D. Mol Interv. 2002 Apr;2(2):101-9. Review. PMID: 14993355 Link
Expedition inspiration consensus 2001.
Benz CC, Hilakivi-Clarke L, Conzen S, Dorn RV, Fleming GF, Grant K, Greene G, Hellman S, Henderson C, Hoover R, Hryniuk W, Jeffrey S, Lippman M, Lung J, Mitchell M, Pike M. Breast Cancer Res Treat. 2001 Dec;70(3):213-9. No abstract available. PMID: 11804185 Link
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications.
Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Eystein Lønning P, Børresen-Dale AL. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74. PMID: 11553815 Link
Breast cancer: variables affecting sentinel lymph node visualization at preoperative lymphoscintigraphy.
Birdwell RL, Smith KL, Betts BJ, Ikeda DM, Strauss HW, Jeffrey SS. Radiology. 2001 Jul;220(1):47-53. PMID: 11425971 Link
Freehand iMRI-guided large-gauge core needle biopsy: a new minimally invasive technique for diagnosis of enhancing breast lesions.
Daniel BL, Birdwell RL, Butts K, Nowels KW, Ikeda DM, Heiss SG, Cooper CR, Jeffrey SS, Dirbas FM, Herfkens RJ. J Magn Reson Imaging. 2001 Jun;13(6):896-902. PMID: 11382950 Link
Locally advanced breast cancer: is surgery necessary?
Favret AM, Carlson RW, Goffinet DR, Jeffrey SS, Dirbas FM, Stockdale FE. Breast J. 2001 Mar-Apr;7(2):131-7. PMID: 11328324 Link
Isosulfan blue affects pulse oximetry.
Vokach-Brodsky L, Jeffrey SS, Lemmens HJ, Brock-Utne JG. Anesthesiology. 2000 Oct;93(4):1002-3. PMID: 11020754 Link
Molecular portraits of human breast tumours.
Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D. Nature. 2000 Aug 17;406(6797):747-52. PMID: 10963602 Link
Controversies in sentinel lymph node biopsy for breast cancer.
Jeffrey SS, Jones SB, Smith KL. Cancer Biother Radiopharm. 2000 Jun;15(3):223-33. Review. PMID: 10941529 Link
Systematic variation in gene expression patterns in human cancer cell lines.
Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D, Brown PO. Nat Genet. 2000 Mar;24(3):227-35. PMID: 10700174 Link
Characterization of breast lesion morphology with delayed 3DSSMT: an adjunct to dynamic breast MRI.
Leong CS, Daniel BL, Herfkens RJ, Birdwell RL, Jeffrey SS, Ikeda DM, Sawyer-Glover AM, Glover GH. J Magn Reson Imaging. 2000 Feb;11(2):87-96. PMID: 10713939 Link
Management of breast cancer after Hodgkin's disease.
Wolden SL, Hancock SL, Carlson RW, Goffinet DR, Jeffrey SS, Hoppe RT. J Clin Oncol. 2000 Feb;18(4):765-72. PMID: 10673517 Link
Radiofrequency ablation of breast cancer: first report of an emerging technology.
Jeffrey SS, Birdwell RL, Ikeda DM, Daniel BL, Nowels KW, Dirbas FM, Griffey SM. Arch Surg. 1999 Oct;134(10):1064-8. PMID: 10522847 Link
Genome-wide analysis of DNA copy-number changes using cDNA microarrays.
Pollack JR, Perou CM, Alizadeh AA, Eisen MB, Pergamenschikov A, Williams CF, Jeffrey SS, Botstein D, Brown PO. Nat Genet. 1999 Sep;23(1):41-6. PMID: 10471496 Link
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers.
Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D, Brown PO, Botstein D. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9212-7. PMID: 10430922 Link
Prior research available in PubMed