VA Palo Alto
The TWC- Lab is located at the Hospital of Veterans Affairs in Palo Alto. Click here to get directions.

Lab News

03-02-15 Joe wins 2015 New Vision Award
Joe had a very successful conference last week, and was awarded the 2015 New Vision Award at the Charleston Conference on Alzheimer’s disease. This is a highly selective award (with money!) which involves a first round of selections to attend the conference and then a study section-like discussion of the remaining entries at the conference. Joe’s proposal was selected unanimously.
01-27-15 Tony speaks at World Economic Forum
Tony was invited to Davos to discuss how to tackle brain diseases at the World Economic Forum!
12-02-14 Final round for Breakthrough of the Year!
We made the final round for Science's 2014 Breakthrough of the year!  Let everyone know so they can vote!
11-13-14 Vote for the breakthrough of the year!
Help us win Sciene Breakthrough of 2014 by voting for "Young blood fixes old."
09-23-14 Creative Minds: Tony and Tom are in the news!
Congratulations to Tony and Tom for being in the NIH Director's blog.  You can read it here!

Research Interests

Immune responses and adult neurogenesis - Neurons and glial cells are constantly produced in small numbers in the adult CNS. In response to injury or tumor growth these numbers can increase dramatically. We discovered that TGF-β1, which is known to limit cell proliferation, is a potent inhibitor of both gliogenesis and neurogenesis in the aging mouse brain. TGF-β1 may have similar effects after injury and limit the potentially beneficial actions of newly generated cells. Current studies in the lab focus on other innate immune molecules as regulators of neurogenesis.