Cold Chain Required: Yes
Manufacturer: Aventis Pasteur
Side Effects: Pain, redness, and swelling or itching at the injection site; headache, nausea, and abdominal pain.
Pre-Exposure Immunogenicity: Induces neutralizing antibodies in 100% of those given the vaccine. This protection requires approximately 7 to 10 days to develop and usually lasts for up to 2 years.
Post-Exposure Immunogenicity: Demonstrated in clinical testing phase to fully protect against rabies.
Who Needs Pre-Exposure Prophylaxis: Veterinarians, animal control officers, spelunkers, wildlife handlers, and travelers going to rabies endemic locations.
Pre-Exposure: Day 0, Day 7, Day 21 or 28
Post-Exposure without Pre-Exposure: Day 0 with immune globulin, Day 3, Day 7, Day 14, Day 28
Post-Exposure with Pre-Exposure: Day 0, Day 3