About Me

I am currently a postdoc in David Kingsley's lab at Stanford University. I am interested in understanding the genetic mutations that have resulted in phenotypic differences between species as well as differences between individuals of the same species.

I did my PhD work in David Haussler's lab at the University of California, Santa Cruz.

My undergraduate degree is in computer science from Cornell University's College of Engineering.

Publications

Lowe CB, Haussler D.
29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome.
PLoS One. 2012;7(8):e43128.

Data

29 mammals sequencing and analysis consortium.
A high-resolution map of human evolutionary constraint using 29 mammals.
Nature. 2011 Oct 12;478(7370):476-82.

Online supplement

Anolis genome sequencing consortium.
The genome of the green anole lizard and a comparative analysis with birds and mammals.
Nature. 2011 Aug 31;477(7366):587-91.

Lowe CB, Kellis M, Siepel A, Raney BJ, Clamp M, Salama SR, Kingsley DM, Lindblad-Toh K, Haussler D.
Three periods of regulatory innovation during vertebrate evolution.
Science. 2011 Aug 19;333(6045):1019-24.

Online supplement

McLean CY, Bristor D, Hiller M, Clarke SL, Schaar BT, Lowe CB, Wenger AM, Bejerano G.
GREAT improves functional interpretation of cis-regulatory regions.
Nat Biotechnol. 2010 May;28(5):495-501.

Lowe CB, Bejerano G, Salama SR, Haussler D.
Endangered species hold clues to human evolution.
J Hered. 2010 Jul-Aug;101(4):437-47.

Zhu J, Sanborn JZ, Diekhans M, Lowe CB, Pringle TH, Haussler D.
Comparative genomics search for losses of long-established genes on the human lineage.
PLoS Comput Biol. 2007 Dec;3(12):e247.

Wang T, Zeng J, Lowe CB, Sellers RG, Salama SR, Yang M, Burgess SM, Brachmann RK, Haussler D.
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53.
Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18613-8.

Lowe CB, Bejerano G, Haussler D.
Thousands of human mobile element fragments undergo strong purifying selection near developmental genes.
Proc Natl Acad Sci U S A. 2007 May 8;104(19):8005-10.

Exaptation data

Bejerano G, Lowe CB, Ahituv N, King B, Siepel A, Salama SR, Rubin EM, Kent WJ, Haussler D.
A distal enhancer and an ultraconserved exon are derived from a novel retroposon.
Nature. 2006 May 4;441(7089):87-90.

A picture of Craig Lowe

Contact Information

Address
Craig Lowe
Stanford Univ. School of Medicine
Dept. of Developmental Biology
279 Campus Drive
Beckman Center B300
Stanford, CA 94305-5329
Email