MBL Neurobiology Course
Madison Web Index
Our laboratory is
located in the Department of
Molecular and Cellular Physiology, Beckman Center for Molecular and
at the Stanford University
School of Medicine.
The School of Medicine is located on the main campus of Stanford
University in Palo
Alto, CA, in the San Francisco
Daniel Madison, Ph.D. , Principal Investigator (email@example.com)
Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission
and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of
synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs
after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling
model for mechanisms underlying memory formation in the mammalian central nervous system. Most
recently, we have been involved in studies of LTP that occurs between individual pairs of neurons.
The other major focus of the lab is the study of the modulation and short term plasticity of inhibitory
synaptic transmission in the hippocampus by different neurotransmitter systems. Projects under this
focus include studies on the modulatory properties of norepinephrine, acetylcholine and opiates on
hippocampal inhibitory circuitry and transmitter release.
Studies in the lab are carried out using a full range of electrophysiological techniques including
extracellular field potential recording, intracellular recording,whole cell and single channel recording in
hippocampal slices and cultured neurons.
Continuum Model of Synaptic Plasticity
State-Model of Synaptic Plasticity
Introduction to the Preparation
Introduction to the Hippocampus
The origin of the membrane potential
The ionic basis of the action potential
Action Potential Conduction and Basis of synaptic transmission
Introduction to sensory transduction
The Madison Lab Project
The Madison Lab and the Search for the Holy Grail on the Madison Lab Renovation
Wassup from the Madison Lab?
Matt as Heather
The Legend of Ricky Jack
This page is now archived. It will no longer be updated. For the current version of the Madison Lab Web Page, please go to http://www.stanford.edu/~madison/madlab
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