Welcome

Marina Sirota
Stanford Center for Biomedical Informatics Research
Medical School Office Building, X-215
251 Campus Drive
Stanford, CA 94305-5479
msirota@stanford.edu


I am currently a Lead Research Scientist in the department of Systems Medicine at Stanford University. I am primarily interested in developing computational methods in integrative biology and applying these methods to study disease.

Previously, I worked as a Senior Scientist at Rinat, Pfizer under the mentorship of David Cox and Jaume Pons. I completed my PhD in Biomedical Informatics and an undergraduate in  Biomedical Computation at Stanford. Before then, I attended Abraham Lincoln High School. As an undergraduate and masters student I worked with Serafim Batzoglou on developing algorithms for comparative sequence analysis, more specifically the problem of gene finding. During my PhD I worked with Atul Butte on a novel approach to identify allele-specific relationships between disease pairs based on genetic variation data and applied it to study autoimmune disease. As a result we uncovered two groupings of autoimmune disease where SNPs that make an individual susceptible to one class of autoimmune disease also protect from diseases in the other autoimmune class. I also developed a systematic approach for predicting drug-disease relationships based on gene expression to identify novel therapeutic indications for known drugs.