Please not that there is NO REQUIRED TEXTBOOK for this class. The reason is simply that we have not been able to find a single text
which covers all of the necessary material. All textbooks listed here are merely suggestions as to where you might look if you desire extra
information.
Introduction to Protein Architecture by Arthur M. Lesk
- This is a very nice book, newly written and designed, which covers a lot of information about protein structure. There are 8 chapters:
- The photosynthetic reaction center: protein structure in a microcosm
- In vivo, in vitro, in silicio
- Pattern and form in protein structure
- The varieties of protein structure
- Molecular Evolution
- Evolution in selected protein families
- Some proteins of the immune system
- Conformational changes in proteins
- It is an especially nice book because it has a ton of beautiful illustrations (a real factor when talking about protein structure), and also
has links to relevant websites at the end of each section. It contains further references, and practice problems as well. Talk to the TA
if you want to preview a copy.
- Buy from Amazon
Biochemistry by Voet and Voet, 2nd Edition
- My own personal favorite general biochemistry textbook, this one is expensive but IMHO worth it, and a great all-around reference. 5
Sections, 34 chapters and over 1200 pages. Sections are:
- I should point out that most of the information presented in this book is entirely irrelevant to the class, but that it does include great
sections on nucleic acids, transcription and translation, enzyme action, and more about metabolism than you could ever want to know.
- Buy from Amazon
Proteins: Structures and Molecular Properties by Thomas E. Creighton, 2nd Edition
- A very comprehensive book on protein structure written from the perspective of a protein chemisty.
- Chapters:
- Chemical Properties of Polypeptides
- Biosynthesis of Proteins
- Evolutionary and Genetic Origins of Protein Sequences
- Physical Interactions That Determine the Properties of Proteins
- Conformational Properties of Polypeptide Chains
- The Folded Conformations of Globular Proteins
- Proteins in Solution and in Membranes
- Interactions with Other Molecules
- Enzyme Catalysis
- Degradation
- Buy from Amazon
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