Participating Labs

The labs in the Stanford Center for Cell Biology are housed in the Biology Department, and are conducting research on a broad range of interesting and important cell biology areas:


Cyert Lab  – cell signaling

Dixon Lab – cell death & metabolism

Feldman Lab – cell  & cytoskeletal patterning

Kopito Lab – protein folding and destruction

Skotheim Lab – systems biology, cell cycle

Stearns Lab – centrosomes, cilia & the cell cycle

Ting Lab – mapping cells and functional circuits



Recent Publications

  1. Rubin, SM, Sage, J, Skotheim, JM. Integrating Old and New Paradigms of G1/S Control. Mol. Cell. 2020; :. doi: 10.1016/j.molcel.2020.08.020. PubMed PMID:32946743 .
  2. Ching, K, Stearns, T. Centrioles are amplified in cycling progenitors of olfactory sensory neurons. PLoS Biol. 2020;18 (9):e3000852. doi: 10.1371/journal.pbio.3000852. PubMed PMID:32931487 .
  3. Valente, LJ, Tarangelo, A, Li, AM, Naciri, M, Raj, N, Boutelle, AM et al.. p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen. J. Cell Biol. 2020;219 (11):. doi: 10.1083/jcb.201908212. PubMed PMID:32886745 .
  4. Riegman, M, Sagie, L, Galed, C, Levin, T, Steinberg, N, Dixon, SJ et al.. Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture. Nat. Cell Biol. 2020;22 (9):1042-1048. doi: 10.1038/s41556-020-0565-1. PubMed PMID:32868903 .
  5. Han, S, Zhao, BS, Myers, SA, Carr, SA, He, C, Ting, AY et al.. RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting. Proc. Natl. Acad. Sci. U.S.A. 2020;117 (36):22068-22079. doi: 10.1073/pnas.2006617117. PubMed PMID:32839320 .
  6. Zatulovskiy, E, Zhang, S, Berenson, DF, Topacio, BR, Skotheim, JM. Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division. Science. 2020;369 (6502):466-471. doi: 10.1126/science.aaz6213. PubMed PMID:32703881 PubMed Central PMC7489475.
  7. Geisinger, JM, Stearns, T. CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Nucleic Acids Res. 2020;48 (16):9067-9081. doi: 10.1093/nar/gkaa603. PubMed PMID:32687165 .
  8. Liang, X, Kokes, M, Fetter, RD, Sallee, MD, Moore, AW, Feldman, JL et al.. Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites. Elife. 2020;9 :. doi: 10.7554/eLife.56547. PubMed PMID:32657271 PubMed Central PMC7375809.
  9. Perez, MA, Magtanong, L, Dixon, SJ, Watts, JL. Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells. Dev. Cell. 2020;54 (4):447-454.e4. doi: 10.1016/j.devcel.2020.06.019. PubMed PMID:32652074 PubMed Central PMC7483868.
  10. Wigington, CP, Roy, J, Damle, NP, Yadav, VK, Blikstad, C, Resch, E et al.. Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling. Mol. Cell. 2020;79 (2):342-358.e12. doi: 10.1016/j.molcel.2020.06.029. PubMed PMID:32645368 PubMed Central PMC7416808.
  11. Inde, Z, Forcina, GC, Denton, K, Dixon, SJ. Kinetic Heterogeneity of Cancer Cell Fractional Killing. Cell Rep. 2020;32 (1):107845. doi: 10.1016/j.celrep.2020.107845. PubMed PMID:32640215 PubMed Central PMC7409774.
  12. Khondker, S, Kajjo, S, Chandler-Brown, D, Skotheim, J, Rudner, A, Ikui, A et al.. PP2ACdc55 dephosphorylates Pds1 and inhibits spindle elongation in S. cerevisiae. J. Cell. Sci. 2020;133 (14):. doi: 10.1242/jcs.243766. PubMed PMID:32591482 PubMed Central PMC7406319.
  13. Bozal-Basterra, L, Gonzalez-Santamarta, M, Muratore, V, Bermejo-Arteagabeitia, A, Da Fonseca, C, Barroso-Gomila, O et al.. LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. Elife. 2020;9 :. doi: 10.7554/eLife.55957. PubMed PMID:32553112 PubMed Central PMC7363444.
  14. Ho, EK, Tsai, AE, Stearns, T. Transient Primary Cilia Mediate Robust Hedgehog Pathway-Dependent Cell Cycle Control. Curr. Biol. 2020;30 (14):2829-2835.e5. doi: 10.1016/j.cub.2020.05.004. PubMed PMID:32531277 .
  15. Nguyen, NUN, Canseco, DC, Xiao, F, Nakada, Y, Li, S, Lam, NT et al.. A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes. Nature. 2020;582 (7811):271-276. doi: 10.1038/s41586-020-2228-6. PubMed PMID:32499640 .
  16. Donnelly, KM, DeLorenzo, OR, Zaya, AD, Pisano, GE, Thu, WM, Luo, L et al.. Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses. Elife. 2020;9 :. doi: 10.7554/eLife.58499. PubMed PMID:32463364 PubMed Central PMC7297539.
  17. Cho, KF, Branon, TC, Rajeev, S, Svinkina, T, Udeshi, ND, Thoudam, T et al.. Split-TurboID enables contact-dependent proximity labeling in cells. Proc. Natl. Acad. Sci. U.S.A. 2020;117 (22):12143-12154. doi: 10.1073/pnas.1919528117. PubMed PMID:32424107 PubMed Central PMC7275672.
  18. Zatulovskiy, E, Skotheim, JM. On the Molecular Mechanisms Regulating Animal Cell Size Homeostasis. Trends Genet. 2020;36 (5):360-372. doi: 10.1016/j.tig.2020.01.011. PubMed PMID:32294416 PubMed Central PMC7162994.
  19. Cyert, MS. Introducing 'Open Questions' article type. Open Biol. 2020;10 (4):200074. doi: 10.1098/rsob.200074. PubMed PMID:32228397 PubMed Central PMC7241077.
  20. Armenta, DA, Dixon, SJ. Investigating Nonapoptotic Cell Death Using Chemical Biology Approaches. Cell Chem Biol. 2020;27 (4):376-386. doi: 10.1016/j.chembiol.2020.03.005. PubMed PMID:32220334 PubMed Central PMC7185180.
  21. Avasthi, P, Feldman, JL. Higher order cytoskeletal structures. Mol. Biol. Cell. 2020;31 (6):398. doi: 10.1091/mbc.E19-12-0679. PubMed PMID:32163347 PubMed Central PMC7185890.
  22. Xie, S, Skotheim, JM. A G1 Sizer Coordinates Growth and Division in the Mouse Epidermis. Curr. Biol. 2020;30 (5):916-924.e2. doi: 10.1016/j.cub.2019.12.062. PubMed PMID:32109398 PubMed Central PMC7158888.
  23. Shipony, Z, Marinov, GK, Swaffer, MP, Sinnott-Armstrong, NA, Skotheim, JM, Kundaje, A et al.. Long-range single-molecule mapping of chromatin accessibility in eukaryotes. Nat. Methods. 2020;17 (3):319-327. doi: 10.1038/s41592-019-0730-2. PubMed PMID:32042188 .
  24. Dubreuil, MM, Morgens, DW, Okumoto, K, Honsho, M, Contrepois, K, Lee-McMullen, B et al.. Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway. Cell Rep. 2020;30 (5):1417-1433.e7. doi: 10.1016/j.celrep.2020.01.013. PubMed PMID:32023459 PubMed Central PMC7184925.
  25. Li, J, Han, S, Li, H, Udeshi, ND, Svinkina, T, Mani, DR et al.. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Cell. 2020;180 (2):373-386.e15. doi: 10.1016/j.cell.2019.12.029. PubMed PMID:31955847 PubMed Central PMC7072036.
  26. Zhang, L, Winkler, S, Schlottmann, FP, Kohlbacher, O, Elias, JE, Skotheim, JM et al.. Multiple Layers of Phospho-Regulation Coordinate Metabolism and the Cell Cycle in Budding Yeast. Front Cell Dev Biol. 2019;7 :338. doi: 10.3389/fcell.2019.00338. PubMed PMID:31921850 PubMed Central PMC6927922.
  27. Sanchez, MI, Ting, AY. Publisher Correction: Directed evolution improves the catalytic efficiency of TEV protease. Nat. Methods. 2020;17 (2):242. doi: 10.1038/s41592-019-0729-8. PubMed PMID:31907448 .
  28. Sanchez, MI, Ting, AY. Directed evolution improves the catalytic efficiency of TEV protease. Nat. Methods. 2020;17 (2):167-174. doi: 10.1038/s41592-019-0665-7. PubMed PMID:31819267 PubMed Central PMC7004888.
  29. Branon, TC, Bosch, JA, Sanchez, AD, Udeshi, ND, Svinkina, T, Carr, SA et al.. Author Correction: Efficient proximity labeling in living cells and organisms with TurboID. Nat. Biotechnol. 2020;38 (1):108. doi: 10.1038/s41587-019-0355-0. PubMed PMID:31748691 .
  30. Brown, CW, Amante, JJ, Chhoy, P, Elaimy, AL, Liu, H, Zhu, LJ et al.. Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export. Dev. Cell. 2019;51 (5):575-586.e4. doi: 10.1016/j.devcel.2019.10.007. PubMed PMID:31735663 .
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