Here is a simple alphabetical list of the drugs, supplements and therapies that are being considered and investigated as potential treatments for Huntington’s Disease. Click on any drug from the list below to find a drug summary and a more in-depth description of drug function and mechanics. If at any time you wish to return to the organization by disease mechanism, click here. You can also click here to reach “Treatment vs. Cure”: An Introduction to HD Drugs and Supplements. (Note: In no way is this list exhaustive or complete, nor are these drugs, supplements and therapies officially advocated or recognized by medical professionals. The information we present is intended for educational purposes only and should not be construed as offering diagnoses or recommendations.)
Drugs, Supplements and Therapies Being Investigated as Potential Treatments:
- Abnormalities in Energy Metabolism: Table of Contents
- Anesthesia and Huntington’s Disease
- Antidepressants and HD
- Antisense Gene Therapy
- Arginine
- Brain-derived neurotrophic factor (BDNF)
- Carnitine
- Caspase-6 inhibition
- Coenzyme-Q10
- Creatine
- Cystamine
- Dichloroacetate
- Dimebon (Latrepirdine)
- Ethyl-EPA (Miraxion, LAX-101)
- Fluoxetine
- Folic Acid
- Gangliosides
- Geldanamycin
- Gene Silencing
- Genome Editing
- Ginkgo Biloba
- Glucocorticoids
- Histones and HDAC Inhibitors
- Lamotrigine
- Lipoic Acid
- Lithium
- Melatonin
- Memantine
- Metal Accumulation in Huntington’s Disease
- Minocycline
- Mithramycin
- Neurotrophic Factors and Huntington’s Disease
- Neurturin
- Nicotinamide
- NSAIDs
- Omega-3 Fatty Acids
- Other Neuroprotective Compounds
- Paroxetine
- Pridopidine (Huntexil, ACR-16)
- Prion-like Behavior in the Huntingtin Protein
- Rapamycin
- Red Wine
- Remacemide
- Retinoic Acid (RA)
- Riboflavin
- Riluzole
- RNA Interference (RNAi)
- Selenium
- SSRIs
- Stem Cells
- Tetrabenazine
- The Heat-Shock Response
- Trehalose
- TRiC and Huntingtin Protein Aggregation
- TUDCA: Tauroursodeoxycholic Acid
- Verapamil
- Vitamin C
- Vitamin D3 (cholecalciferol)
- Vitamin E
- XIAP Gene Therapy