Publications

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2020
Miao Y, Ha A, de Lau W, et al. "Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
2019
Zhao L, Jin Y, Donahue K, et al. "Tissue Repair in the Mouse Liver Following Acute Carbon Tetrachloride Depends on Injury-Induced Wnt/β-Catenin Signaling." Hepatology (Baltimore, Md.). 2019;69(6):2623-2635. Abstract
2018
Przybyl J, Kidzinski L, Hastie T, Debiec-Rychter M, Nusse R, van de Rijn M. "Gene expression profiling of low-grade endometrial stromal sarcoma indicates fusion protein-mediated activation of the Wnt signaling pathway." Gynecologic oncology. 2018;149(2):388-393. Abstract
Wan DC, Morgan SL, Spencley AL, et al. "Honey bee Royalactin unlocks conserved pluripotency pathway in mammals." Nature communications. 2018;9(1):5078. Abstract
2014
Rinkevich Y, Montoro DT, Contreras-Trujillo H, et al. "In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration." Cell reports. 2014;7(4):1270-83. Abstract
2013
Chu ML, Ahn VE, Choi HJ, Daniels DL, Nusse R, Weis WI. "structural Studies of Wnts and identification of an LRP6 binding site." Structure (London, England : 1993). 2013;21(7):1235-42. Abstract
Ardehali R, Ali SR, Inlay MA, et al. "Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(9):3405-10. Abstract
Green JL, La J, Yum KW, et al. "Paracrine Wnt signaling both promotes and inhibits human breast tumor growth." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(17):6991-6. Abstract
2008
Morrell NT, Leucht P, Zhao L, et al. "Liposomal packaging generates Wnt protein with in vivo biological activity." PLoS One. 2008;3:e2930. Abstract
2005
Gordon MD, Dionne MS, Schneider DS, Nusse R. "WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity." Nature. 2005;437:746-749. Abstract
2004
Galli LM, Willert K, Nusse R, et al. "A proliferative role for Wnt-3a in chick somites." Dev Biol. 2004;269:489-504. Abstract
Kuhnert F, Davis CR, Wang H-T, et al. "Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1." Proc Natl Acad Sci U S A. 2004;101:266-271. Abstract
Derksen PWB, Tjin E, Meijer HP, et al. "Illegitimate WNT signaling promotes proliferation of multiple myeloma cells." Proc Natl Acad Sci U S A. 2004;101:6122-6127. Abstract
2003
Reya T, Duncan AW, Ailles L, et al. "A role for Wnt signalling in self-renewal of haematopoietic stem cells." Nature. 2003;423:409-414. Abstract
Willert K, Brown JD, Danenberg E, et al. "Wnt proteins are lipid-modified and can act as stem cell growth factors." Nature. 2003;423:448-452. Abstract
2000
Reya T, O'Riordan M, Okamura R, et al. "Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism." Immunity. 2000;13:15-24. Abstract
1999
Hsieh JC, Kodjabachian L, Rebbert ML, et al. "A new secreted protein that binds to Wnt proteins and inhibits their activities." Nature. 1999;398:431-436. Abstract
1990
Schuuring E, van der Leede BJ, Willems R, et al. "Differentiation-dependent expression of provirus-activated int-1 oncogene in clonal cell lines derived from a mouse mammary tumor." Oncogene. 1990;5:459-465. Abstract
van Leeuwen F, Van de Vijver MJ, Lomans J, et al. "Mutation of the human neu protein facilitates down-modulation by monoclonal antibodies." Oncogene. 1990;5:497-503. Abstract
1989
Schuuring E, van Deemter L, Roelink H, Nusse R. "Transient expression of the proto-oncogene int-1 during differentiation of P19 embryonal carcinoma cells." Mol Cell Biol. 1989;9:1357-1361. Abstract
1988
Van de Vijver MJ, Peterse JL, Mooi WJ, et al. "Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer." N Engl J Med. 1988;319:1239-1245. Abstract
1987
van de Vijver M, van de Bersselaar R, Devilee P, Cornelisse C, Peterse J, Nusse R. "Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene." Mol Cell Biol. 1987;7:2019-2023. Abstract
Rijsewijk F, van Deemter L, Wagenaar E, Sonnenberg A, Nusse R. "Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity." EMBO J. 1987;6:127-131. Abstract
1979
Nusse R, van der Ploeg L, van Duijn L, Michalides R, Hilgers J. "Impaired maturation of mouse mammary tumor virus precursor polypeptides in lymphoid leukemia cells, producing intracytoplasmic A particles and no extracellular B-type virions." J Virol. 1979;32:251-258. Abstract
Demant P, Ivanyi D, Nusse R, Neauport-Sautes C, Snoek M. "H-2L locus: alleles, products, and specificities." Transplant Proc. 1979;11:647-651.