Publications
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The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators." Annual review of biochemistry. 2022;91:571-598. Abstract
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Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo." Cell stem cell. 2020;27(5):840-851.e6. Abstract
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β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism." Molecular biology of the cell. 2020;31(13):1425-1436. Abstract
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A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis." Genes & development. 2019;33(3-4):209-220. Abstract
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Gene expression profiling of low-grade endometrial stromal sarcoma indicates fusion protein-mediated activation of the Wnt signaling pathway." Gynecologic oncology. 2018;149(2):388-393. Abstract
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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals." Nature communications. 2018;9(1):5078. Abstract
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Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands." Gastroenterology. 2015;148(7):1392-1404.e21. Abstract
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Paracrine Wnt signaling both promotes and inhibits human breast tumor growth." Proceedings of the National Academy of Sciences of the United States of America. 2013;110(17):6991-6. Abstract
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ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour." The Journal of pathology. 2012;227(2):223-33. Abstract
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Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination." Nature neuroscience. 2011;14(8):1009-16. Abstract
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Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma." Oncogene. 2009;28:2513-2523. Abstract
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A dermal HOX transcriptional program regulates site-specific epidermal fate." Genes Dev. 2008;22:303-307. Abstract
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Wnt signaling during Caenorhabditis elegans embryonic development." Methods Mol Biol. 2008;469:103-111. Abstract
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Wnt signaling regulates pancreatic beta cell proliferation." Proc Natl Acad Sci U S A. 2007;104:6247-6252. Abstract
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A role for Wnt signalling in self-renewal of haematopoietic stem cells." Nature. 2003;423:409-414. Abstract
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Wnt proteins are lipid-modified and can act as stem cell growth factors." Nature. 2003;423:448-452. Abstract
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Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes." Science. 2002;296:1118-1120. Abstract
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The status of Wnt signalling regulates neural and epidermal fates in the chick embryo." Nature. 2001;411:325-330. Abstract
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Information access. Building a "GenBank" of the published literature." Science. 2001;291:2318-2319.
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Naked cuticle targets dishevelled to antagonize Wnt signal transduction." Genes Dev. 2001;15:658-671. Abstract
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Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless." Mol Cell. 2000;6:117-126. Abstract
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Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism." Immunity. 2000;13:15-24. Abstract
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