MANAGEMENT AND THERAPY [10]

Taeniasis:

The treament of taeniasis with anthelimintic drugs is often sufficient to eliminate the parasite. The treatment plan of choice is to administer a single-dose of praziquantel (5-10 mg/kg). Praziquantel acts by increasing the permeability of the cell membrane, resulting in a efflux of intracellular calcium. This efflux leads to muscle tetany and the eventual paralysis and elimination of the worm. In cases of taeniasis, praziquantel has close to a 100% effectiveness rate.

The final step required in taeniasis treatment is the weekly examination of the patient's stools for gravid proglottids for 5 weeks after praziquantel administration. This monitoring ensures the clearance of the parasite.

 

Neurocysticercosis:

The treatment of neurocysticercosis is much more complicated than the treatment for taeniasis and is evaluated often on a patient-by-patient basis. Surgical intervention may be a viable option in some cases. In other cases, an anthelmintic drug (i.e.praziquantel) might be prescribed. However, if an anthelmintic agent is used, a glucocorticoid is also prescribed to relieve the inflammation caused by the death of cysticerci in organ tissue (recall action of praziquantel).