Next: Informal pointers for choosing
Up: Estimation of (the number
Previous: Steps in estimating
  Contents
When there is real population structure, this leads to LD among
unlinked loci and departures from Hardy-Weinberg proportions. Roughly
speaking, this is the signal that is used by the structure
algorithm. But some departures from the model can also lead to
Hardy-Weinberg or linkage disequilibrium. These include inbreeding,
and genotyping errors such as occasional, undetected, null
alleles. Even in the absence of population structure, these types of
factors can lead to a weak statistical signal for .
Beginning in Version 2, we have suggested that the correlated allele
frequency model should be used as a default because it often achieves
better performance on difficult problems, but the user should be
aware that this may make it easier to overestimate in such
settings than under the independent frequencies model.
The next subsection discusses how to decide whether inferred structure
is real.
Next: Informal pointers for choosing
Up: Estimation of (the number
Previous: Steps in estimating
  Contents
Jonathan Pritchard
2003-07-10