Calendar

Feb
19
Wed
2020
Deploying AI in the Clinical Radiology Workflow: Challenges, Opportunities, and Examples @ Clark Center S360
Deploying AI in the Clinical Radiology Workflow: Challenges, Opportunities, and Examples
Feb 19 @ 2:00 pm – 3:00 pm Clark Center S360
Deploying AI in the Clinical Radiology Workflow: Challenges, Opportunities, and Examples @ Clark Center S360

Tessa Cook, MD, PhD
Assistant Professor of Radiology
Perelman School of Medicine
University of Pennsylvania

Title: Deploying AI in the Clinical Radiology Workflow: Challenges, Opportunities, and Examples

Abstract: Although many radiology AI efforts are focused on pixel-based tasks, there is great potential for AI to impact radiology care delivery and workflow when applied to reports, EMR data, and workflow data. Radiology-pathology correlation, identification of follow-up recommendations, and report segmentation can be used to increase meaningful feedback to radiologists as well as to automate tasks that are currently manual and time-consuming. When deploying AI within the clinical workflow, there are many challenges that may slow down or otherwise affect the integration. Careful consideration of the way in which radiologists may expect to interact with AI results should be undertaken to meaningfully deploy radiology AI in a safe and effective way.

Mar
6
Fri
2020
CANCELLED - MIPS Seminar - Pritha Ray, Ph.D. @ James H. Clark Center, S360
CANCELLED – MIPS Seminar – Pritha Ray, Ph.D.
Mar 6 @ 11:00 am – 12:00 pm James H. Clark Center, S360
CANCELLED - MIPS Seminar - Pritha Ray, Ph.D. @ James H. Clark Center, S360

Please note this seminar is now cancelled and will be rescheduled for a later date. 

MIPS Seminar: Investigating and Imaging key molecular switches associated with Acquirement of Platinum-Taxol resistance in Epithelial Ovarian Cancer

Pritha Ray, Ph.D.

Principal Investigator & Scientific Officer F
Imaging Cell Signaling & Therapeutics Lab
ACTREC, Tata Memorial Center
Navi Mumbai, India

 

Apr
22
Wed
2020
CANCELLED - IMAGinING THE FUTURE - Elias Zerhouni, M.D. @ CANCELLED
CANCELLED – IMAGinING THE FUTURE – Elias Zerhouni, M.D.
Apr 22 @ 1:00 pm – 2:30 pm CANCELLED
CANCELLED - IMAGinING THE FUTURE - Elias Zerhouni, M.D. @ CANCELLED

Please note this seminar is now cancelled and will be rescheduled for a future date. Please contact Ashley Williams (ashleylw@stanford.edu) with any questions or concerns. Thank you for your understanding!

 

IMAGinING THE FUTURE: “Journey Through Academia, Government and Industry: Lessons Learned”

Elias Zerhouni, M.D.

Professor Emeritus

John Hopkins University

 

IBIIS/AIMI Seminar - Tiwari @ ZOOM - See Description for Zoom link
IBIIS/AIMI Seminar – Tiwari
Apr 22 @ 1:00 pm – 2:00 pm ZOOM - See Description for Zoom link
IBIIS/AIMI Seminar - Tiwari @ ZOOM - See Description for Zoom link

Radiomics and Radio-Genomics: Opportunities for Precision Medicine

Zoom: https://stanford.zoom.us/j/99904033216?pwd=U2tTdUp0YWtneTNUb1E4V2x0OTFMQT09 

Pallavi Tiwari, PhD
Assistant Professor of Biomedical Engineering
Associate Member, Case Comprehensive Cancer Center
Director of Brain Image Computing Laboratory
School of Medicine | Case Western Reserve University


Abstract:
In this talk, Dr. Tiwari will focus on her lab’s recent efforts in developing radiomic (extracting computerized sub-visual features from radiologic imaging), radiogenomic (identifying radiologic features associated with molecular phenotypes), and radiopathomic (radiologic features associated with pathologic phenotypes) techniques to capture insights into the underlying tumor biology as observed on non-invasive routine imaging. She will focus on clinical applications of this work for predicting disease outcome, recurrence, progression and response to therapy specifically in the context of brain tumors. She will also discuss current efforts in developing new radiomic features for post-treatment evaluation and predicting response to chemo-radiation treatment. Dr. Tiwari will conclude with a discussion on her lab’s findings in AI + experts, in the context of a clinically challenging problem of post-treatment response assessment on routine MRI scans.

May
7
Thu
2020
SMIS Quarterly Seminar
May 7 @ 12:00 pm – 1:00 pm Zoom:

Stanford Molecular Imaging Scholars (SMIS) Program
Quarterly Seminar

Andrew Groll, PhD
Mentor: Craig Levin, PhD
“Initial Experimental Images from a CZT Preclinical PET System”

Brian Lee, PhD
Mentors: Sam Gambhir, MD, PhD; Craig Levin, PhD
“Precision Health Toilet for Cancer Screening”

 

Aug
4
Tue
2020
SMIS Quarterly Seminar @ Zoom:
SMIS Quarterly Seminar
Aug 4 @ 12:00 pm – 1:00 pm Zoom:
SMIS Quarterly Seminar @ Zoom:

Stanford Molecular Imaging Scholars (SMIS) Program Quarterly Seminar

Zoom meeting: https://stanford.zoom.us/j/99117388314?pwd=R29OSjlTdUt0a3pLaG5Zc1BFNTJIUT09
Password: 922183

Guolan Lu, PhD
Mentor: Eben Rosenthal, MD; Garry Nolan, PhD
“Co-administered Antibody Improves the Penetration of Antibody-Dye Conjugates into Human Cancers: Implications for AntibodyDrug Conjugates”

Dianna Jeong, PhD
Mentors: Craig Levin, PhD; Shan Wang, PhD
“Novel Detection Approaches for Achieving Ultra-fast time resolution for PET”

 

Sep
16
Wed
2020
IBIIS & AIMI Seminar - Judy Gichoya, MD @ Zoom - See Description for Zoom Link
IBIIS & AIMI Seminar – Judy Gichoya, MD
Sep 16 @ 12:00 pm – 1:00 pm Zoom - See Description for Zoom Link
IBIIS & AIMI Seminar - Judy Gichoya, MD @ Zoom - See Description for Zoom Link

Judy Gichoya, MD
Assistant Professor
Emory University School of Medicine

Measuring Learning Gains in Man-Machine Assemblage When Augmenting Radiology Work with Artificial Intelligence

Abstract
The work setting of the future presents an opportunity for human-technology partnerships, where a harmonious connection between human-technology produces unprecedented productivity gains. A conundrum at this human-technology frontier remains – will humans be augmented by technology or will technology be augmented by humans? We present our work on overcoming the conundrum of human and machine as separate entities and instead, treats them as an assemblage. As groundwork for the harmonious human-technology connection, this assemblage needs to learn to fit synergistically. This learning is called assemblage learning and it will be important for Artificial Intelligence (AI) applications in health care, where diagnostic and treatment decisions augmented by AI will have a direct and significant impact on patient care and outcomes. We describe how learning can be shared between assemblages, such that collective swarms of connected assemblages can be created. Our work is to demonstrate a symbiotic learning assemblage, such that envisioned productivity gains from AI can be achieved without loss of human jobs.

Specifically, we are evaluating the following research questions: Q1: How to develop assemblages, such that human-technology partnerships produce a “good fit” for visually based cognition-oriented tasks in radiology? Q2: What level of training should pre-exist in the individual human (radiologist) and independent machine learning model for human-technology partnerships to thrive? Q3: Which aspects and to what extent does an assemblage learning approach lead to reduced errors, improved accuracy, faster turn-around times, reduced fatigue, improved self-efficacy, and resilience?

Zoom: https://stanford.zoom.us/j/93580829522?pwd=ZVAxTCtEdkEzMWxjSEQwdlp0eThlUT09

Nov
18
Wed
2020
IBIIS & AIMI Seminar: Deep Tomographic Imaging @ Zoom: https://stanford.zoom.us/j/96731559276?pwd=WG5zcEFwSGlPcDRsOUFkVlRhcEs2Zz09
IBIIS & AIMI Seminar: Deep Tomographic Imaging
Nov 18 @ 12:00 pm – 1:00 pm Zoom: https://stanford.zoom.us/j/96731559276?pwd=WG5zcEFwSGlPcDRsOUFkVlRhcEs2Zz09

Ge Wang, PhD
Clark & Crossan Endowed Chair Professor
Director of the Biomedical Imaging Center
Rensselaer Polytechnic Institute
Troy, New York

Abstract:
AI-based tomography is an important application and a new frontier of machine learning. AI, especially deep learning, has been widely used in computer vision and image analysis, which deal with existing images, improve them, and produce features. Since 2016, deep learning techniques are actively researched for tomography in the context of medicine. Tomographic reconstruction produces images of multi-dimensional structures from externally measured “encoded” data in the form of various transforms (integrals, harmonics, and so on). In this presentation, we provide a general background, highlight representative results, and discuss key issues that need to be addressed in this emerging field.

About:
AI-based X-ray Imaging System (AXIS) lab is led by Dr. Ge Wang, affiliated with the Department of Biomedical Engineering at Rensselaer Polytechnic Institute and the Center for Biotechnology and Interdisciplinary Studies in the Biomedical Imaging Center. AXIS lab focuses on innovation and translation of x-ray computed tomography, optical molecular tomography, multi-scale and multi-modality imaging, and AI/machine learning for image reconstruction and analysis, and has been continuously well funded by federal agencies and leading companies. AXIS group collaborates with Stanford, Harvard, Cornell, MSK, UTSW, Yale, GE, Hologic, and others, to develop theories, methods, software, systems, applications, and workflows.

Jan
28
Thu
2021
MIPS Seminar - Carolyn Bertozzi, PhD @ Zoom - See Description for Zoom Link
MIPS Seminar – Carolyn Bertozzi, PhD
Jan 28 @ 12:00 pm – 12:45 pm Zoom - See Description for Zoom Link
MIPS Seminar - Carolyn Bertozzi, PhD @ Zoom - See Description for Zoom Link

MIPS Seminar Series: Translational Opportunities in Glycoscience

Carolyn Bertozzi, PhD
Director, ChEM-H
Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences
Professor, by courtesy, of Chemical and Systems Biology
Stanford University

 

Location: Zoom
Webinar URL: . https://stanford.zoom.us/j/94010708043
Dial: US: +1 650 724 9799  or +1 833 302 1536 (Toll Free)
Webinar ID: 940 1070 8043
Passcode: 659236

12:00pm – 12:45pm Seminar & Discussion
RSVP Here

 

ABSTRACT
Cell surface glycans constitute a rich biomolecular dataset that drives both normal and pathological processes.  Their “readers” are glycan-binding receptors that can engage in cell-cell interactions and cell signaling.  Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies.  Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities based on the concept of targeted degradation.

 

ABOUT
Carolyn Bertozzi is the Baker Family Director of Stanford ChEM-H and the Anne T. and Robert M. Bass Professor of Humanities and Sciences in the Department of Chemistry at Stanford University. She is also an Investigator of the Howard Hughes Medical Institute. Her research focuses on profiling changes in cell surface glycosylation associated with cancer, inflammation and infection, and exploiting this information for development of diagnostic and therapeutic approaches, most recently in the area of immuno-oncology. She is an elected member of the National Academy of Medicine, the National Academy of Sciences, and the American Academy of Arts and Sciences. She also has been awarded the Lemelson-MIT Prize, a MacArthur Foundation Fellowship, the Chemistry for the Future Solvay Prize, among many others.

 

Hosted by: Katherine Ferrara, PhD
Sponsored by: Molecular Imaging Program at Stanford & the Department of Radiology

Feb
25
Thu
2021
MIPS Seminar - Joseph M. DeSimone, PhD @ Zoom - See Description for Zoom Link
MIPS Seminar – Joseph M. DeSimone, PhD
Feb 25 @ 12:00 pm – 12:45 pm Zoom - See Description for Zoom Link
MIPS Seminar - Joseph M. DeSimone, PhD @ Zoom - See Description for Zoom Link

MIPS Seminar Series: “Convergent, translational research to improve human health”

Joseph M. DeSimone, PhD
Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering
Departments of Radiology and Chemical Engineering
Graduate School of Business (by Courtesy)
Stanford University

 

Location: Zoom
Webinar URL: https://stanford.zoom.us/s/98460805010
Dial: +1 650 724 9799 or +1 833 302 1536
Webinar ID: 984 6080 5010
Passcode: 809226

12:00pm – 12:45pm Seminar & Discussion
RSVP Here

 

ABSTRACT
In many ways, manufacturing processes define what’s possible in society.  Central to our interests in the DeSimone laboratory are opportunities to make things using cutting-edge fabrication technologies that can improve human health.  This lecture will describe advances in nano- / micro-fabrication and 3D printing technologies that we have made and employed toward this end.  Using novel perfluoropolyether materials synthesized in our lab in 2004, we invented the Particle Replication in Non-wetting Templates (PRINT) technology, a high-resolution imprint lithography-based process to fabricate nano- and micro-particles with precise and independent control over particle parameters (e.g. size, shape, modulus, composition, charge, surface chemistry).  PRINT brought the precision and uniformity associated with computer industry manufacturing technologies to medicine, resulting in the launch of Liquidia Technologies (NASDAQ: LQDA) and opening new research paths, including to elucidate the influence of specific particle parameters in biological systems (Proc. Natl. Acad. Sci. USA 2008), and to reveal insights to inform the design of vaccines (J. Control. Release 2018), targeted therapeutics (Nano Letters 2015), and even synthetic blood (PNAS 2011).  In 2015, we reported the invention of the Continuous Liquid Interface Production (CLIP) 3D printing technology (Science 2015), which overcame major fundamental limitations in polymer 3D printing—slowness, a very limited range of materials, and an inability to create parts with the mechanical and thermal properties needed for widespread, durable utility.  By rethinking the physics and chemistry of 3D printing, we created CLIP to eliminate layer-by-layer fabrication altogether.  A rapid, continuous process, CLIP generates production-grade parts and is now transforming how products are manufactured in industries including automotive, footwear, and medicine.  For example, to help address shortages, CLIP recently enabled a new nasopharyngeal swab for COVID-19 diagnostic testing to go from concept to market in just 20 days, followed by a 400-patient clinical trial at Stanford.  Academic laboratories are also using CLIP to pursue new medical device possibilities, including geometrically complex IVRs to optimize drug delivery and implantable chemotherapy absorbers to limit toxic side effects.  Vast opportunities exist to use CLIP to pursue next-generation medical devices and prostheses.  Moreover, CLIP can improve current approaches; for example, the fabrication of an iontophoretic device we invented several years ago (Sci. Transl. Med. 2015) to drive chemotherapeutics directly into hard-to-reach solid tumors is now being optimized for clinical trials with CLIP.  New design opportunities also exist in early detection, for example to improve specimen collection, device performance (e.g. microfluidics, cell sorting, supporting growth and studies with human organoids), and imaging (e.g. PET detectors, ultrasound transducers).  Here at Stanford, we are pursuing new 3D printing advances, including software treatment planning for digital therapeutic devices in pediatric medicine, as well as the design of a high-resolution printer capable of single-digit micron resolution to advance microneedle designs as a potent delivery platform for vaccines.  The impact of our work on human health ultimately relies on our ability to enable a convergent research program to take shape that allows for new connections to be made among traditionally disparate disciplines and concepts, and to ensure that we maintain a consistent focus on the translational potential of our discoveries and advances.

 

ABOUT
Joseph M. DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University. He holds appointments in the Departments of Radiology and Chemical Engineering with a courtesy appointment in Stanford’s Graduate School of Business. Previously, DeSimone was a professor of chemistry at the University of North Carolina at Chapel Hill and of chemical engineering at North Carolina State University. He is also Co-founder, Board Chair, and former CEO (2014 – 2019) of the additive manufacturing company, Carbon.

DeSimone is responsible for numerous breakthroughs in his career in areas including green chemistry, medical devices, nanomedicine, and 3D printing, also co-founding several companies based on his research. He has published over 350 scientific articles and is a named inventor on over 200 issued patents. Additionally, he has mentored 80 students through Ph.D. completion in his career, half of whom are women and members of underrepresented groups in STEM. In 2016 DeSimone was recognized by President Barack Obama with the National Medal of Technology and Innovation, the highest U.S. honor for achievement and leadership in advancing technological progress. He is also one of only 25 individuals elected to all three branches of the U.S. National Academies (Sciences, Medicine, Engineering). DeSimone received his B.S. in Chemistry in 1986 from Ursinus College and his Ph.D. in Chemistry in 1990 from Virginia Tech.

 

Hosted by: Katherine Ferrara, PhD
Sponsored by: Molecular Imaging Program at Stanford & the Department of Radiology