Calendar

Sep
6
Fri
2019
CCSB Seminar: Identifying and Rationally Modulating Cellular Drivers of Tumor Response @ Clark Center S360
Sep 6 @ 11:00 am – 12:00 pm
CCSB Seminar: Identifying and Rationally Modulating Cellular Drivers of Tumor Response @ Clark Center S360

Alex K. Shalek, PhD
Pfizer-Laubach Career Development Associate Professor
Institute for Medical Engineering & Science
Department of Chemistry and Koch Institute
Massachusetts Institute of Technology

Abstract: While several methods exist for sampling tissues in clinical contexts, without high-fidelity tools for comprehensively profiling them, we are both limited in our capacity to understand how constituent cells and their interactions impact prognosis, and to select and develop precision therapeutics. Recent years have witnessed transformative and intersecting advances in nanofabrication and molecular biology that now enable deep profiling of low-input samples. Collectively, these afford new and exciting opportunities to study cellular heterogeneity, starting from the level of the single cell, and may unlock the diagnostic, prognostic, and discovery potential of clinical isolates. Illustratively, I will introduce how we can leverage single-cell genomic approaches – and, in particular, single-cell RNA-Seq – to explore the extensive functional diversity between cells, uncovering, from the “bottom-up,” distinct cell states and their molecular drivers. Moreover, I will discuss high-throughput experimental strategies and demonstrate, in the context of Acute Lymphoblastic Leukemia, how they can be leveraged to achieve the statistical power necessary to reconstruct intracellular circuits, enumerate and redefine cell states and types, and transform our understanding of cellular decision-making in health and disease on a genomic scale.

Bio: Alex K. Shalek is currently the Pfizer-Laubach Career Development Associate Professor at MIT, as well as a Core Member of the Institute for Medical Engineering and Science (IMES), an Associate Professor of Chemistry, and an Extramural Member of The Koch Institute for Integrative Cancer Research. He is also an Institute Member of the Broad Institute, an Associate Member of the Ragon Institute, an Assistant in Immunology at MGH, and an Instructor in Health Sciences and Technology at HMS. His research is directed towards the development and application of new technologies that facilitate understanding of how cells collectively perform systems-level functions in healthy and diseased states. Dr. Shalek received his bachelor’s degree summa cum laude from Columbia University and his Ph.D. from Harvard University in chemical physics under the guidance of Hongkun Park, and performed postdoctoral training under Hongkun Park and Aviv Regev (Broad/MIT). To date, his interdisciplinary research has focused on realizing and utilizing nanoscale manipulation and measurement technologies to examine how small components (molecules, cells) drive systems of vast complexity (cellular responses, population behaviors).

Mar
26
Thu
2020
Thursday MIPS Roundtable – Heike Daldrup-Link, M.D. @ Zoom - See Description for Zoom Link
Mar 26 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable - Heike Daldrup-Link, M.D. @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: “Ask the Radiologist about COVID-19”

 

Hosted by Dr. Heike Daldrup-Link & Dr. Gunilla Jacobson

Join us virtually to ask anything you would like to know about COVID-19 and the current status in our community. This week we will open the floor for questions. Please prepare questions related to COVID-19. Feel free to submit questions in advance to Ashley Williams (ashleylw@stanford.edu) or submit them in the chat on Zoom.

Meeting URL: https://stanford.zoom.us/j/186504700
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 186 504 700c talking about the future of medicine and science.

Apr
2
Thu
2020
Thursday MIPS Roundtable – Kathy Ferrara, Ph.D. & Angie Louie, Ph.D. @ Zoom - See Description for Zoom Link
Apr 2 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable - Kathy Ferrara, Ph.D. & Angie Louie, Ph.D. @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable

Hosted by Dr. Kathy Ferrara & Dr. Gunilla Jacobson

Join us virtually to ask anything you would like to know about career plans, collaborations, new expertise and online lectures during the shutdown. Feel free to submit questions in advance to Ashley Williams (ashleylw@stanford.edu) or submit them in the chat on Zoom.

 

1:30-2:00 PM | Dr. Kathy Ferrara, Ph.D.

“Developing a career plan, collaborations and new expertise during the shutdown”

Professor of Radiology
Stanford University

2:00-2:30 PM | Dr. Angie Louie, Ph.D.

“How to create online lectures using Camtasia, Playposit and Canvas”

Professor of Biomedical Engineering
UC Davis

 

Meeting URL: https://stanford.zoom.us/j/186504700
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 186 504 700

Apr
9
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
Apr 9 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: ePad: A Web-based Imaging Informatics Platform for Image Annotation and Quantitative Analysis

Come learn about ePAD (https://epad.stanford.edu) from Dr. Rubin’s lab, a freely-accessible web-based informatics platform for universal access to radiology images, annotations, and quantitative analysis. We’ll also open the floor to a discussion on integrating ePAD into the SCi3 preclinical imaging workflow and how together we can crowdsource data sharing and reuse, and accelerate quantitative imaging research for everyone.

Daniel Rubin, PhD
Professor of Biomedical Data Science, of Radiology, of Medicine, and, by courtesy, Ophthalmology and of Computer Science

Jason Thanh Lee, PhD
Director of the Clark Center Facility

Laura Pisani, PhD
Associate Director of the Clark Center Facility

Frezghi Habet, PhD
Director of the Porter Drive Facility

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

Please note Zoom information does change week to week.

4/9 Meeting URL: https://stanford.zoom.us/j/114866791
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 114 866 791

Apr
16
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
Apr 16 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Dr. Michelle James & Dr. Ted Graves

 

1:30-2:00 PM – Michelle L. James, Ph.D.

Neuroimmune Imaging Research and Discovery (NiRD) Lab

Assistant Professor of Radiology and of Neurology

Stanford University

 

2:00-2:30 PM – Edward “Ted” Graves, Ph.D.

Imaging Radiobiology Laboratory, Division of Radiation Oncology Medical Physics

“Using Imaging to Study Radiation Biology”

Associate Professor of Radiation Oncology (Radiation Physics) and, by courtesy, of Radiology

Stanford University

 

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

4/16 Meeting URL: https://stanford.zoom.us/j/406957830
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 406 957 830

Apr
23
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
Apr 23 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Thera(g)nostics: Current clinical use and future needs

1:30-2:15 PM | Dr. Carina Mari Aparici, M.D.

Thera(g)nostics: Current clinical use and future needs

Bringing the clinical needs with preclinical research efforts

Clinical Professor of Radiology – Nuclear Medicine

Director, Targeted Radionuclide Therapy Program

Stanford University

 

2:15-2:30 PM | Dr. Gunilla Jacobson, Ph.D.

MIPS Theranostics Interest Group

How to join and learn more

Deputy Director

Molecular Imaging Program at Stanford, Radiology

Stanford University

 

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

4/23 Meeting URL: https://stanford.zoom.us/j/639510777
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 639 510 777

Apr
30
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
Apr 30 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Faculty Lab Showcase

 

1:30-2:00 PM | Dr. Guillem Pratx, Ph.D.

The Physical Oncology Lab

Assistant Professor of Radiation Oncology (Radiation Physics)

Stanford University

 

2:00-2:30 PM | Dr. Craig Levin, Ph.D.

Molecular Imaging Instrumentation Laboratory

Professor of Radiology and, by courtesy, of Physics,
of Electrical Engineering and of Bioengineering

Stanford University

 

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

4/30 Meeting URL: https://stanford.zoom.us/j/630252651
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 630 252 651

May
7
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
May 7 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Faculty Lab Showcase

 

1:30-2:00 PM | Dr. Raag Airan, M.D., Ph.D.

Airan Lab: Noninvasive Control of the Nervous System

Assistant Professor of Radiology and, by courtesy, of Materials Science and Engineering and of Psychiatry and Behavioral  Sciences

Stanford University

 

2:00-2:30 PM | Dr. Daniel Spielman, Ph.D.

The Spielman Laboratory: In Vivo MR Spectroscopy and Multinuclear Imaging

Professor of Radiology and, by courtesy, of Electrical Engineering

Stanford University

 

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

5/7 Meeting URL: https://stanford.zoom.us/j/91812578814
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 918 1257 8814

May
14
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
May 14 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Faculty Lab Showcase

 

1:30-2:00 PM | Dr. Gozde Durmus, Ph.D.

Levitating Cells for Applications in Biology and Medicine

Assistant Professor of Radiology

Stanford University

 

2:00-2:30 PM | Dr. Ramasamy Paulmurugan, Ph.D.

Cellular Pathway Imaging Laboratory (CPIL)

Associate Professor of Radiology

Stanford University

 

MIPS Roundtables will be every Thursday through May from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

5/14 Meeting URL: https://stanford.zoom.us/j/97661102825
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 976 6110 2825

May
21
Thu
2020
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link
May 21 @ 1:30 pm – 2:30 pm
Thursday MIPS Roundtable @ Zoom - See Description for Zoom Link

Thursday MIPS Roundtable: Faculty Lab Showcase

 

1:30-2:00 PM | Dr. Sandip Biswal, M.D.

Biswal Lab for Pain Imaging

Associate Professor of Radiology

Stanford University

 

2:00-2:30 PM | Dr. Lei Xing, Ph.D.

Xing Lab: Where Sciences & Engineering Meet Medicine

Jacob Haimson Professor and Professor, by courtesy, of Electrical Engineering

Stanford University

 

MIPS Roundtables will be every Thursday from 1:30-2:30pm showcasing various topics and are open to all interested.

 

Please note Zoom information does change week to week.

5/21 Meeting URL: https://stanford.zoom.us/j/98018934679
Dial: +1 650 724 9799 or +1 833 302 1536
Meeting ID: 980 1893 4679