Calendar

Sep
6
Fri
2019
CCSB Seminar: Identifying and Rationally Modulating Cellular Drivers of Tumor Response @ Clark Center S360
Sep 6 @ 11:00 am – 12:00 pm
CCSB Seminar: Identifying and Rationally Modulating Cellular Drivers of Tumor Response @ Clark Center S360

Alex K. Shalek, PhD
Pfizer-Laubach Career Development Associate Professor
Institute for Medical Engineering & Science
Department of Chemistry and Koch Institute
Massachusetts Institute of Technology

Abstract: While several methods exist for sampling tissues in clinical contexts, without high-fidelity tools for comprehensively profiling them, we are both limited in our capacity to understand how constituent cells and their interactions impact prognosis, and to select and develop precision therapeutics. Recent years have witnessed transformative and intersecting advances in nanofabrication and molecular biology that now enable deep profiling of low-input samples. Collectively, these afford new and exciting opportunities to study cellular heterogeneity, starting from the level of the single cell, and may unlock the diagnostic, prognostic, and discovery potential of clinical isolates. Illustratively, I will introduce how we can leverage single-cell genomic approaches – and, in particular, single-cell RNA-Seq – to explore the extensive functional diversity between cells, uncovering, from the “bottom-up,” distinct cell states and their molecular drivers. Moreover, I will discuss high-throughput experimental strategies and demonstrate, in the context of Acute Lymphoblastic Leukemia, how they can be leveraged to achieve the statistical power necessary to reconstruct intracellular circuits, enumerate and redefine cell states and types, and transform our understanding of cellular decision-making in health and disease on a genomic scale.

Bio: Alex K. Shalek is currently the Pfizer-Laubach Career Development Associate Professor at MIT, as well as a Core Member of the Institute for Medical Engineering and Science (IMES), an Associate Professor of Chemistry, and an Extramural Member of The Koch Institute for Integrative Cancer Research. He is also an Institute Member of the Broad Institute, an Associate Member of the Ragon Institute, an Assistant in Immunology at MGH, and an Instructor in Health Sciences and Technology at HMS. His research is directed towards the development and application of new technologies that facilitate understanding of how cells collectively perform systems-level functions in healthy and diseased states. Dr. Shalek received his bachelor’s degree summa cum laude from Columbia University and his Ph.D. from Harvard University in chemical physics under the guidance of Hongkun Park, and performed postdoctoral training under Hongkun Park and Aviv Regev (Broad/MIT). To date, his interdisciplinary research has focused on realizing and utilizing nanoscale manipulation and measurement technologies to examine how small components (molecules, cells) drive systems of vast complexity (cellular responses, population behaviors).

Mar
27
Fri
2020
Mini-Grand Rounds – Aruna Subramanian, MD, and David Ha, PharmD @ Zoom
Mar 27 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Aruna Subramanian, MD, and David Ha, PharmD @ Zoom

Mini-Grand Rounds: Emerging treatment strategies for COVID-19

Aruna Subramanian, MD
Clinical Professor, Medicine
Stanford University

David Ha, PharmD
Infectious Disease Resident
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Mar
30
Mon
2020
Mini-Grand Rounds – Payam Massaband, MD @ Zoom
Mar 30 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Payam Massaband, MD @ Zoom

Mini-Grand Rounds: Effective faculty-trainee workflow and education during the COVID-19 pandemic

Payam Massaband, MD
Clinical Associate Professor, Radiology
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
3
Fri
2020
Mini-Grand Rounds – Michele Barry, MD, FACP @ Zoom
Apr 3 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Michele Barry, MD, FACP @ Zoom

Mini-Grand Rounds: CoVID19:  Lessons learned from the global response

Michele Barry, MD, FACP
Drs. Ben & A. Jess Shenson Professor
Senior Associate Dean, Global Health
Director, Center for Innovation in Global Health
Professor of Medicine & Senior Fellow at the Woods Institute and at the Freeman Spogli Institute

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
6
Mon
2020
Mini-Grand Rounds – Garry Gold, MD @ Zoom
Apr 6 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Garry Gold, MD @ Zoom

Mini-Grand Rounds: How to stay productive during the COVID-19 pandemic

Garry Gold, MD
Vice Chair, Research and Organization
Professor, Radiology
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
8
Wed
2020
Mini-Grand Rounds – Shanthi Kappagoda, MD, MS
Apr 8 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Shanthi Kappagoda, MD, MS

Mini-Grand Rounds: Update on COVID-19

Shanthi Kappagoda, MD, MS
Clinical Associate Professor, Medicine – Infectious Diseases
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
10
Fri
2020
Mini-Grand Rounds – Alison Kerr @ Zoom
Apr 10 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Alison Kerr @ Zoom

Mini-Grand Rounds: SHC preparedness and mitigation plans for the COVID-19 pandemic

Alison Kerr
Vice President, Neuroscience and Orthopedic Service Lines
CAO of Clinical Operations
Stanford Health Care

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
13
Mon
2020
Mini-Grand Rounds – Sam Shen, MD, PhD @ Zoom
Apr 13 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Sam Shen, MD, PhD @ Zoom

Mini-Grand Rounds: In the frontlines of the COVID-19 pandemic

Sam Shen, MD, MBA
Associate Chief Quality Officer/Patient Safety Officer, SHC
Vice Chair, Clinical Operations & Quality
Clinical Associate Professor, Emergency Medicine
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
15
Wed
2020
Mini-Grand Rounds – Terry Desser, MD @ Zoom
Apr 15 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Terry Desser, MD @ Zoom

Mini-Grand Rounds: Well-being during the COVID-19 pandemic

Terry Desser, MD
Professor, Radiology
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.

Apr
17
Fri
2020
Mini-Grand Rounds – Tina Hernandez-Boussard, MPH, PhD @ Zoom
Apr 17 @ 7:00 am – 7:30 am
Mini-Grand Rounds - Tina Hernandez-Boussard, MPH, PhD @ Zoom

Mini-Grand Rounds: COVID-19: Meeting the Challenge with Data Science

Tina Hernandez-Boussard, MPH, PhD
Professor, Radiology
Stanford University

7:00am – 7:30am, Zoom

The Stanford Radiology Mini-Grand Round live session events are by invitation only. Invites with link to Zoom video will be sent via email to Department faculty and staff only. Recordings will be made available to the public shortly after the event.