Calendar

Feb
16
Wed
2022
IBIIS & AIMI Seminar: Imaging Analytics for Neuro-Oncology: Towards Computational Diagnostics @ ZOOM: https://stanford.zoom.us/j/98789338790?pwd=OXRORjhYUUdaRGJpUHJZdzZ5NGw5dz09
Feb 16 @ 12:00 pm – 1:00 pm

Spyridon (Spyros) Bakas, PhD
Assistant Professor in the Department of Pathology,
Laboratory Medicine, and of Radiology
Center for Biomedical Image Computing and Analytics (CBICA)
Perelman School of Medicine
University of Pennsylvania

Title: Imaging Analytics for Neuro-Oncology:
Towards Computational Diagnostics

Abstract: Central nervous system (CNS) tumors come with vastly heterogeneous histologic, molecular, and radiographic landscapes, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics have shown promise in better characterizing the molecular, spatial, and temporal heterogeneity of tumors. Integrative analysis of CNS tumors, including clinically acquired multi-parametric magnetic resonance imaging (mpMRI), assists in identifying macroscopic quantifiable tumor patterns of invasion and proliferation, potentially leading to improved (a) detection/segmentation of tumor subregions and (b) computer-aided diagnostic/prognostic/predictive modeling. This talk will touch upon example studies on this space, as well as an overview of the largest to-date real-world federated learning study to detect brain tumor boundaries.

Mar
16
Wed
2022
IBIIS & AIMI Seminar: Using AI for Longitudinal Tumor Response Monitoring and AI Guided Cancer Treatments: From Lab to Clinic @ ZOOM: https://stanford.zoom.us/j/99319571697?pwd=c2lhRkN4cXEzTzFzMUhKaTVJMHZLQT09
Mar 16 @ 12:00 pm – 1:00 pm

Harini Veeraraghavan, PhD
Associate Attending Computer Scientist
Department of Medical Physics
Memorial Sloan-Kettering Cancer Center

Using AI for Longitudinal Tumor Response Monitoring and AI Guided Cancer Treatments: From Lab to Clinic

Abstract:
Cancer patients are imaged with multiple imaging modalities as part of routine cancer care. However, the rich information available from the images are not fully exploited to better manage patient care through earlier intervention as well as more precise targeted treatments. In this talk, I will present some of the new AI methodologies we have been developing to track tumor response as well as from routinely acquired imaging applied to image-guided radiation treatments using CT/cone-beam CT as well as MRI-guided precision treatments. I will also present some demonstration studies of how AI based automated segmentation and tumor as well as healthy tissue change assessment can be used to early detect treatment toxicities to enable clinicians to better manage cancer care. Finally, I will show how these developed methods have been put to routine clinical care for automating radiotherapy treatment planning at MSK.

Apr
14
Thu
2022
IBIIS & AIMI Seminar: Imaging Analytics for Neuro-Oncology: Towards Computational Diagnostics @ Zoom: https://stanford.zoom.us/j/98789338790?pwd=OXRORjhYUUdaRGJpUHJZdzZ5NGw5dz09
Apr 14 @ 11:00 am – 12:00 pm

Spyridon (Spyros) Bakas, PhD
Assistant Professor in the Department of Pathology,
Laboratory Medicine, and of Radiology
Center for Biomedical Image Computing and Analytics (CBICA)
Perelman School of Medicine
University of Pennsylvania

Title: Imaging Analytics for Neuro-Oncology: Towards Computational Diagnostics

Central nervous system (CNS) tumors come with vastly heterogeneous histologic, molecular, and radiographic landscapes, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics have shown promise in better characterizing the molecular, spatial, and temporal heterogeneity of tumors. Integrative analysis of CNS tumors, including clinically acquired multi-parametric magnetic resonance imaging (mpMRI), assists in identifying macroscopic quantifiable tumor patterns of invasion and proliferation, potentially leading to improved (a) detection/segmentation of tumor subregions and (b) computer-aided diagnostic/prognostic/predictive modeling. This talk will touch upon example studies on this space, as well as an overview of the largest to-date real-world federated learning study to detect brain tumor boundaries.

Apr
20
Wed
2022
IBIIS & AIMI Seminar: Automated Workflows for Neuro-Oncology Image Analysis @ Zoom: https://stanford.zoom.us/j/94439662481?pwd=N1BUc2FqWUt4QVlQMnNSS21rcEV4UT09
Apr 20 @ 12:00 pm – 1:00 pm

Daniel Marcus, PhD
Professor of Radiology
Director of the Neuroinformatics Research Group
Director of the Neuroimaging Informatics and Analysis Center
Washington University

Abstract:
Developing and deploying computational tools for neuro-oncology applications includes a sequence of complex steps to identify appropriate images, assess image quality, annotate, process and other prepare and manipulate data for analysis. We have implemented services and tools on the open source XNAT informatics platform to automate much of this workflow to improve both its efficiency and effectiveness. Dr. Marcus will discuss this automated workflow and its implementation in a number of data sets and applications at Washington University.

May
18
Wed
2022
IBIIS & AIMI Seminar: Missing the (Bench)mark? @ Zoom: https://stanford.zoom.us/j/95872488712?pwd=dDhmT1JPdWtTSlBOQ1BENmtGOUxjUT09
May 18 @ 9:30 am – 10:30 am

Lena Maier-Hein, PhD
Head of Department, Computer Assisted Medical Interventions
Managing Director, Data Science and Digital Oncology
Managing Director, National Center for Tumor Diseases
German Cancer Research Center

Title: Missing the (Bench)mark?

Abstract

Machine learning has begun to revolutionize almost all areas of health research. Success stories cover a wide variety of application fields ranging from radiology and gastroenterology all the way to mental health. Strikingly, however, solutions that perform favorably in research generally do not translate well to clinical practice, and little attention is being given to learning from failures. Focusing on biomedical image analysis as a key area of health-related machine learning, this talk will present pitfalls, caveats and recommendations related to machine learning-based biomedical image analysis. As a particular highlight, it will cover yet unpublished work on two key research questions related to biomedical image analysis competitions: 1) How can we best select performance metrics according to the characteristics of the driving biomedical question? And 2) Why is the winner the best? The results have been compiled based on the input of hundreds of image analysis researchers worldwide.

Jun
16
Thu
2022
IBIIS & AIMI Seminar: Medical AI Safety – A Clinical Perspective @ Zoom: https://stanford.zoom.us/j/93524639045?pwd=NUV1MFE2clBCYVp3K0FJNlJFTGswdz09
Jun 16 @ 4:00 pm – 5:00 pm


Lauren Oakden-Rayner, PhD
Director of Research in Medical Imaging
Royal Adelaide Hospital
Senior Research Fellow
Australian Institute for Machine Learning

Title: Medical AI Safety – A Clinical Perspective

Abstract:
Medical artificial intelligence is rapidly moving into clinics, particularly in imaging-based specialties such as radiology. This transition is producing many new challenges, as the regulatory environment has struggled to keep up and AI training for healthcare workers is virtually non-existent. Dr. Oakden-Rayner will provide a clinical safety perspective on medical AI, discuss a range of identified risks and potential harms, and discuss possible solutions to mitigate these risks as this exciting field continues to develop.

Bio:
Dr. Lauren Oakden-Rayner (FRANZCR, PhD) is the Director of Research in Medical Imaging at the Royal Adelaide Hospital and is a senior research fellow at the Australian Institute for Machine Learning. Her research explores the safe translation of artificial intelligence technologies into clinical practice, both from a technical and clinical perspective.

Sep
21
Wed
2022
IBIIS & AIMI Seminar: Ethical Challenges in the Application of AI to Healthcare @ ZOOM: https://stanford.zoom.us/j/99191454207?pwd=N0ZYWnh1Mks0UEluOVRUZjdWNHZPUT09
Sep 21 @ 1:30 pm – 2:30 pm

David Magnus, PhD
Thomas A Raffin Professor of Medicine and Biomedical Ethics and Professor of Pediatrics, Medicine, and by courtesy of Bioengineering
Director, Stanford Center for Biomedical Ethics
Associate Dean for Research
Stanford University

Title: Ethical Challenges in the Application of AI to Healthcare

Abstract:
This presentation will focus on three issues. First, applying AI to healthcare requires access to large data sets. Data acquisition and data sharing raises a number of challenging ethical issues, including challenges to traditional understandings of informed consent, and importance of diversity and inclusion in data sources. Second, I will briefly discuss the widely discussed issues around justice and equity raised by AI in healthcare. Finally, I will discuss challenges with ethical oversight and governance, particularly in relation to research development of AI. IRB’s are prohibited from considering downstream social consequences and harms to individuals other than research participants when evaluating the harms and risks of research. This gap needs to be filled, particularly as dual uses of AI models are now recognized as a problem.

Bio:
David Magnus, PhD is Thomas A. Raffin Professor of Medicine and Biomedical Ethics and Professor of Pediatrics and Medicine and by Courtesy of Bioengineering at Stanford University, where he is Director of the Stanford Center for Biomedical Ethics and an Associate Dean of Research. Magnus is member of the Ethics Committee for the Stanford Hospital. He is currently the Vice-Chair of the IRB for the NIH Precision Medicine Initiative (“All of Us”). He is the former President of the Association of Bioethics Program Directors, and is the Editor in Chief of the American Journal of Bioethics. He has published articles on a wide range of topics in bioethics, including research ethics, genetics, stem cell research, organ transplantation, end of life, and patient communication. He was a member of the Secretary of Agriculture’s Advisory Committee on Biotechnology in the 21st Century and currently serves on the California Human Stem Cell Research Advisory Committee. He is the principal editor of a collection of essays entitled “Who Owns Life?” (2002) and his publications have appeared in New England Journal of Medicine, Science, Nature Biotechnology, and the British Medical Journal. He has appeared on many radio and television shows including 60 Minutes, Good Morning America, The Today Show, CBS This Morning, FOX news Sunday, and ABC World News and NPR. In addition to his scholarly work, he has published Opinion pieces in the Philadelphia Inquirer, the Chicago Tribune, the San Jose Mercury News, and the New Jersey Star Ledger.

Oct
19
Wed
2022
IBIIS & AIMI Seminar: Learning to Read X-Ray: Applications to Heart Failure Monitoring @ ZOOM: https://stanford.zoom.us/j/93555578704?pwd=eTdhRHM4K0w5WGVmSElSWGkzN3VqQT09
Oct 19 @ 12:00 pm – 1:00 pm

Polina Golland, PhD
Professor of Electrical Engineering and Computer Science
PI in the Computer Science and Artificial Intelligence Laboratory
Massachusetts Institute of Technology

Title: Learning to Read X-Ray: Applications to Heart Failure Monitoring

Abstract: We propose and demonstrate a novel approach to training image classification models based on large collections of images with limited labels. We take advantage of availability of radiology reports to construct joint multimodal embedding that serves as a basis for classification. We demonstrate the advantages of this approach in application to assessment of pulmonary edema severity in congestive heart failure that motivated the development of the method.

Nov
16
Wed
2022
IBIIS & AIMI Seminar: Advanced Prostate Cancer Imaging @ Zoom: https://stanford.zoom.us/j/99807942044?pwd=TmJkclNkbVBZOG04KzJaSFRWVXlxZz09
Nov 16 @ 12:00 pm – 1:00 pm

Baris Turkbey, MD, FSAR
Senior Clinician
Section Chief of MRI
Section Chief of Artificial Intelligence
Molecular Imaging Branch
National Cancer Institute, NIH

Title: Advanced Prostate Cancer Imaging

Talk Objectives: 

  • To discuss current status and limitations of localized prostate cancer diagnosis.
  • To discuss use of artificial intelligence in diagnosis of localized prostate cancer.
  • To discuss use of molecular imaging in clinical prostate cancer management.

Bio:
Dr. Turkbey obtained his medical degree from Hacettepe University in Ankara, Turkey in 2003. He completed his residency in Diagnostic and Interventional Radiology at Hacettepe University. He joined Molecular Imaging Branch (MIB), National Cancer Institute, NIH in 2007. His main research areas are imaging of prostate cancer (multiparametric MRI, PET CT), image guided biopsy and treatment techniques (focal therapy, surgery and radiation therapy) for prostate cancer and artificial intelligence. Dr. Turkbey is a member of Prostate Imaging Reporting & Data System (PI-RADS) Steering Committee. He is the Director Magnetic Resonance Imaging section in MIB and the Artificial Intelligence Resource in MIB.

Dec
14
Wed
2022
IBIIS & AIMI Hybrid Seminar: Anthony Gatti, PhD & Liangqiong Qu, PhD @ Clark Center S360
Dec 14 @ 1:00 pm – 2:00 pm

In Person at the Clark Center S360 – Lunch will be provided!
Zoom: https://stanford.zoom.us/j/99496515255?pwd=MHlXbXM2WXJULzZwemk1WjJHNFZOdz09

Anthony Gatti, PhD
Postdoctoral Research Fellow
Department of Radiology
Wu Tsai Human Performance Alliance
Stanford University

Title: Towards Understanding Knee Health Using Automated MRI-Based Statistical Shape Models

Abstract: Knee injuries and pain are prevalent across all ages, with varying causes from “anterior knee pain” in runners to osteoarthritis-related pain. Osteoarthritis pain is a particular problem because structural outcomes assessed on medical images often disagree with symptoms. Most studies trying to understand knee health and pain use simple biomarkers such as mean cartilage thickness. My talk will present an automated pipeline for quantifying the whole knee using statistical shape modeling. I will present a conventional statistical shape model as well as a novel approach that uses generative neural implicit representations. Both modeling approaches allow unsupervised identification of salient anatomic features. I will demonstrate how these features can be used to predict existing radiographic outcomes, patient demographics, and knee pain.

Liangqiong Qu, PhD
Postdoctoral Research Fellow
Department of Biomedical Data Sciences
Stanford University

Title: Distributed Deep Learning in Medical Imaging

Abstract: Distributed deep learning is an emerging research paradigm for enabling collaboratively training deep learning models without sharing patient data.
In this talk, we will first investigate the use distributed deep learning to build medical imaging classification models in a real-world collaborative setting.
We then present several strategies to tackle the data heterogeneity challenge and the lack of quality labeled data challenge in distributed deep learning.