Recent Highlights
(1) Tuning the Geometric and Electronic Structure of Synthetic High-Valent Iron(IV)-Oxo Models in the Presence of a Lewis Acid and Various Axial Ligands Ehudin, M. A.; Gee, L. B.; Sabuncu, S.; Braun, A.; Moënne-Loccoz, P.; Hedman, B.; Hodgson, K. O.; Solomon, E. I. and Karlin, K. D J. Am. Chem. Soc. 2019, 141, 5942. [DOI: 10.1021/jacs.9b00795]
(2) Geometric and Electronic Structure Contributions to O−O Cleavage and the Resultant Intermediate Generated in Heme-Copper Oxidases. Schaefer, A. W.; Roveda, A. C.; Jose, A. and Solomon, E. I., J. Am. Chem. Soc. 2019, 141, 10068. [DOI: doi.org/10.1021/jacs.9b04271]
(3) O2 Reduction to Water by High Potential Multicopper Oxidases: Contributions of the T1 Copper Site Potential and the Local Environment of the Trinuclear Copper Cluster. Sekretaryova, A.; Jones, S.M.; Solomon, E.I., J. Am. Chem. Soc. 2019, 141, 11304. [DOI: 10.1021/jacs.9b05230]
(4) Characterization of the Preprocessed Copper Site Equilibrium in Amine Oxidase and Assignment of the Reactive Copper Site in Topaquinone Biogenesis. Adelson, C. N.; Johnston, E. M.; Hilmer, K. M.; Watts, H.; Dey, S. G.; Brown, D. E.; Broderick, J. B.; Shepard, E. M.; Dooley, D. M. and Solomon, E. I. , J. Am. Chem. Soc. 2019, 141, 8877. [DOI: 10.1021/jacs.9b01922]
(5) X-ray Absorption Spectroscopy as a Probe of Ligand Noninnocence in Metallocorroles: The Case of Copper Corroles. Lim, H.; Thomas, K.E.; Hedman, B.; Hodgson, K.O.; Ghosh, A.; Solomon, E.I., Inorg. Chem. 2019, 58, 6722. [DOI: 10.1021/acs.inorgchem.9b00128]
(6) Influence of intramolecular secondary sphere hydrogen-bonding interactions on cytochrome c oxidase inspired low-spin heme–peroxo–copper complexes. Ehudin, M.A.; Schaefer, A.W.; Adam, S.M.; Quist, D.A.; Diaz, D.E.; Tang, J.A.; Solomon, E.I. and Karlin, K.D., Chem. Sci. 2019, 10, 2893. [DOI: 10.1039/C8SC05165H]
(7) Evaluation of a concerted vs. sequential oxygen activation mechanism in α-ketoglutarate– dependent nonheme ferrous enzymes." Goudarzi, S.; Iyer, S.R.; Babicz, J.T; Yan, J.J.; Peters, G.H.J.; Christensen, H.E.M.; Hedman, B.; Hodgson, K.O. and Solomon, E.I., PNAS 2020, 117, 5152. [DOI: 10.1073/pnas.1922484117]
(8) Kinetic analysis of amino acid radicals formed in H2O2-driven CuI LPMO reoxidation implicates dominant homolytic reactivity. Jones, S.M.; Transue, W.J.; Meier, K.K.; Kelemen, B. and Solomon E.I., PNAS 2020, 117, 11916. [DOI: 10.1073/pnas.1922499117]
(9) Rapid Decay of the Native Intermediate in the Metallooxidase Fet3p Enables Controlled FeII Oxidation for Efficient Metabolism. Jones, S.M.; Heppner, D.E.; Vu, K.; Kosman, D.J. and Solomon, E.I., J. Am. Chem. Soc. 2020, 142, 10087. [DOI: 10.1021/jacs.0c02384]
(10) A Binuclear CuA Center Designed in an All α-Helical Protein Scaffold. Mirts, E.N.; Dikanov, S.A.; Jose, A.; Solomon, E.I.; and Lu, Y., J. Am. Chem. Soc. 2020, 142, 13779. [DOI: 10.1021/jacs.0c04226]
