Orf Virus

www.acponline.org/bioterro/ anthrax/orf.htm

In animals, an Orf infection is also called contagious pustular dermatitis, ecthyma contagiosum, pustular ecthyma, and "scabby mouth."

Epidemiology

Orf is an infectious dermatitis affecting primarily the hooves and orifices of sheep, goats, and wild ungulates (deer and reindeer). Humans usually acquire the infection by close contact with infected animals and accidental inoculation through cuts or abrasions on the hand. Person to person transmission is rare. Orf virus disease is found worldwide and most commonly affects farm workers, shepherds, and veterinarians. The disease is self-limiting and isn't included in international lists of reportable diseases.

Incubation Period

The incubation period lasts 3-6 days.

Symptomatology and outcomes

The typical skin lesion is solitary, but occasionally, several bumpy lesions are present, each measuring up to 3cm in diameter, persisting for approximately 35 days and regressing spontaneously. The lesions begin as vesicles and then evolve into nodular masses with central umbilication. With secondary bacterial infections, lesions may become pustular. Lesions usually last 35 days and resolve completely. No reports exist of mortality.

Prevention and management

Orf infection can be prevented by avoiding contact with animals exhibiting skin lesions. As a preventive measure, good personal hygiene and washing the exposed area with soap and water is recommended in the Control of Communicable Disease Manual by Chin.

Since Orf recovers spontaneously in 3 to 6 weeks, no specific treatment is necessary in most cases. The lesions can be covered to prevent the environment or transmission to other people even though person-to-person spread is very uncommon. Large lesions can be removed by "shave excision."