Xenopus Wnt genes

 

See the comparative table of all vertebrate Wnt genes for and explanation of the numbering/nomenclature.

Phenotype/
Effect

Duplication Axis in Xenopus (yes/no) or Other Functions

 Gene

  

 Wnt-1
yes
McMahon,1989

 Wnt-2
yes
Landesman 1997
Wnt-2B

 Wnt-3

  

 Wnt-3A
yes
Wolda 1993

 Wnt-4
no
Ungar 1995

 Wnt-5A
no
Torres 1996
but yes with HFz5 He 1997 or Fz4 (Umbhauer, 2000)

Wnt-5B

  

 Wnt-6

  Neural crest inducer (Garcia-Castro, 2002)

 Wnt-7A

  

 Wnt-7B

 yes (J.Brown, Pers. Comm)

 Wnt-8A
yes
Christian 1993

 Wnt-8B
yes
Cui 1995
Wnt-10A

 Wnt-10B

  

 Wnt-11
yes in Ku 1993
no in Du 1995
Cardiogenesis (Pandur 2002)
Activates beta-catenin and is the maternal axis inducer (Tao, 2005)
Required for heart morphogenesis Garriock 2005