**ABOUT THIS IMAGE.** This image illustrates the strict upper bound
that exists on the value of
*F*_{ST} at a locus given the frequency of the most
frequent allele.

The y-axis represents *F*_{ST}, and the x-axis is the
frequency *M* of the most frequent allele. Both axes range from 0
to 1. The gray region represents the set of allowable values
of *F*_{ST} given *M*. The colored rectangles
represent counts of the number of microsatellite loci that have values of
(*M*, *F*_{ST}) in particular 0.01 x 0.01 regions,
for data on 101 Africans and 63 Native Americans. Darker points represent
larger numbers of loci. The figure is based on the work of Jakobsson,
Edge & Rosenberg (The
relationship between *F*_{ST} and the frequency of the most
frequent allele; *Genetics* 193: 515-528, 2013).

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