Rosenberg lab at Stanford University


ABOUT THIS IMAGE. HAPLOSCOPE plot of variation in the lactase region of the human genome.

At each genomic location, relative frequencies of haplotype clusters are shown on a thin vertical line. Each color depicts a haplotype cluster, and the proportion of a line in a color gives the frequency of the cluster associated with the color. The long high-frequency cluster in European populations, quantified by the plot of haplotype cluster homozygosity at the lower right corner, reflects a selective sweep in the lactase region. The figure is based on the work of Jakobsson, Scholz, Scheet, et al. (Genotype, haplotype and copy-number variation in worldwide human populations; Nature 451: 998-1003, 2008).


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