Wyss-Coray Lab

News Flash!!
  • Andrew's discovery of two tRNA synthetases that can be used to label proteins in mammalian cells with click tyrosine or click phenylalanine was just published in JACS. I have a feeling the bio-orthogonal labeling field will be excited about this one!
  • Nick received a scholarship to attend the Comparative and Experimental Approaches to Aging Biology at MDI Biological Laboratory in Maine this summer. The incredible Tabula Muris that he managed is also now online in advance publicaiton on BioRxiv! Keep it up Nick!
  • Vidhu is leaving us, but she has an awesome new job nearby in South San Francisco at Annexon biosciences working on microglia. Congrats Vidhu!
  • Clinical trial finds blood-plasma infusions for Alzheimer's safe, promising:
  • Congratulation to Jian Luo for getting his paper "Deficiency in neuronal TGF-beta signaling leads to nigrostriatal degeneration and activation of TGF-beta signaling protects against MPTP neurotoxicity in mice” accepted in Journal of Neuroscience!​
Wyss-Coray Lab

The Wyss-Coray research team studies brain aging and neurodegeneration with a focus on age-related cognitive decline and Alzheimer’s disease. The team is studying how circulatory blood factors can modulate brain structure and function and how factors from young organisms can rejuvenate old brains. We are trying to understand the molecular basis of the systemic communication with the brain by employing a combination of genetic, cell biology, and –omics approaches in killifish, mice, and humans and through the development of bio-orthogonal tools for the in vivo labeling of proteins.

Affiliations and Support:

The Wyss-Coray lab is part of the Glenn Center for Aging at Stanford, the Stanford Neurosciences Institute’s Brain Rejuvenation Project, The NIH Alzheimer’s Disease Research Center, and it is funded by the Department of Veterans Affairs, the National Institute on Aging, the Cure Alzheimer’s Fund, and the NOMIS Foundation.

More on the lab can be found here:

New Yorker article
TED Talk
News Feature in Nature
article in The Guardian