Frequently asked questions:
The name Wnt is an amalgam of the two founding members: int-1 in the mouse (now called Wnt-1; int stands for integration site, Nusse and Varmus 1982) and wingless in Drosophila. See Nusse et al, 1991. Other Wnt genes have been numbered according to their order of discovery. Wnt genes termed A and B are grouped as close relatives, diverging rather late in evolution (Sidow A) If possible, orthologs in different species have been given corresponding numbers, but there are some exceptions (such as in Drosophila)
No. You can contact me if you have any questions about new genes.
- Is there an official Wnt society or
Yes but acknowledge the source.
- Can I freely use pictures from the Wnt
I try to include as much as possible, but the diagrams and literature references are not intended to give a complete overview of the literature. The Wnt pathway is increasingly becoming more complex and new participants are still being uncovered. One example is the RNAi screen by DasGupta et al. (2005) identifying a further 237 components. It becomes hard to include all of these new components and the list below is selective. See the simplified map for a further selection. This site does not keep track of alternative pathways, such as the planar polarity pathway.
- Is the view of Wnt signaling as presented here
complete and unbiased?
The Wnt meeting is organized ad hoc. There is a separate list of meetings.
- When is the next Wnt meeting?
Between 5000-6000 per month.
- How many hits does the Wnt homepage get?