Robotic Ultrasound Guidance of Radiation Therapy

Project Description

The curative potential of external beam radiation therapy is critically dependent on having the ability to accurately aim radiation beams at intended targets while avoiding surrounding healthy tissues. However existing radiotherapy-guidance technologies are incapable of real-time, volumetric, soft-tissue imaging during radiation beam delivery, when accurate target tracking is most critical. We are addressing this challenge in the development and evaluation of a novel, minimally interfering, robotic ultrasound imaging system that can be integrated with existing medical linear accelerators for therapy guidance. The project is supported by the Stanford Bio-X Interdisciplinary Initiatives Program and Philips Ultrasound.

External website: http://hristovlab.stanford.edu/research/telerobotic_ultrasound_imaging.html

News:

Related Publications

Schlosser, J., Salisbury, JK., Hristov, D, “Online image-based monitoring of soft-tissue displacements for radiation therapy of the prostate,” International Journal of Radiation Oncology, Biology, Physics (to appear)

Schlosser, J., Salisbury, JK., Hristov, D, “Telerobotic system concept for real-time soft-tissue imaging during radiotherapy beam delivery”, Medical Physics 37(12), 6357-6367, 2010. §Featured on the cover of Medical Physics. §§Featured in article on medicalphysicsweb.org.

Schlosser, J., Salisbury, JK., Hristov, D, “Hybrid X-Ray/Ultrasound Imaging Approach for Patient Positioning and Real-Time Tracking in IGRT”,  Joint AAPM/COMP Meeting, Vancouver, Canada, 2011.

Schlosser, J., Salisbury, JK., Hristov, D, “Tissue Displacement Monitoring for Prostate and Liver IGRT Using a Robotically-Controlled Ultrasound System”,  Joint AAPM/COMP Meeting, Vancouver, Canada, 2011. §Featured as “talking point” on medicalphysicsweb.org and on auntminnie.com

Schlosser, J., Salisbury, JK., Hristov, D, “Image-Based Approach to Respiratory Gating for Liver Radiotherapy Using a Telerobotic Ultrasound System”,  ASTRO 53rd Annual Meeting, Miami, FL, 2011

Schlosser, J., Salisbury, JK., Hristov, D, “In-vivo Tissue Displacement Monitoring for Prostate IGRT Using a Telerobotic Ultrasound System”,  ASTRO 53rd Annual Meeting, Miami, FL, 2011

Schlosser, J., Salisbury, JK., Jeffrey, RB., Hristov, D., “Real-Time Soft-Tissue Imaging Concurrent with External Beam Radiation Therapy Delivery”, AAPM 52nd Annual Meeting, Philadelphia, PA, 2010. §2nd place prize in Young Investigator’s Symposium

Schlosser, J., Salisbury, JK., Hristov, D, “Evaluation of a Telerobotic System Concept For Real-Time Soft-Tissue Image Guidance During Radiotherapy Delivery”,  ASTRO 52nd Annual Meeting, San Diego, CA, 2010.

Hristov, D., Schlosser, J., Salisbury, JK., Oralkan, O., Khuri-Yakub, P., “Real-Time-Image Guidance in Radiation Therapy: Is There a Role for Ultrasound Imaging?”, American Association of Physicists Medicine 52nd Annual Meeting, Philadelphia, PA, 2010.

Project Staff

Status

Active since 2008.

Funding Sources

The project is supported by the Stanford Bio-X Interdisciplinary Initiatives Program and Philips Ultrasound.