Wyss-Coray Lab

current members
Alumni
Alumni
Current
Phone: 650 852 3220
Fax: 650 849 1983
Office: 3801 Miranda Ave, 154-W
Office: Bldg 4, Rm. B230
Office: Palo Alto, CA 94304
Dr. Tony Wyss-Coray
Professor
twc[at]stanford.edu
Over-expression of TGF-β1 has been demonstrated by Dr. Wyss-Coray to reduce Aβ deposition in brain parenchyma of APP transgenic mice. I am currently working on a drug-screening project searching for small-molecule compounds that mimic the beneficial effect of TGF-β1.
Hui Zhang
Research Scientist/Lab Manager
huizhang[at]stanford.edu
I was trained as a cell biologist during my Ph.D. studies in Vienna, Austria at the Institute of Molecular Pathology (IMP) in the lab of Juergen Knoblich. In 2003, I moved to Stanford working in the lab of Liqun Luo as a postdoctoral fellow on developmental neurobiology, particularly interested in the assembly and maintenance of neural circuits. I joined the Wyss-Coray lab in January 2011. I am using proteomics approaches to discover novel signaling pathways associated with aging and neurodegenerative diseases.
Daniela Berdnik
Research Scientist
berdnik[at]stanford.edu
Benoit has obtained his master in biostatics from Paul Sabatier University (Toulouse France) and his Ph.D. in Neuroscience from Blaise Pascal University (Clermont Ferrand, France). His main interest lies in the development of new biostatistical approaches to better understand complex biological processes. During his doctoral studies, he used BOLD fMRI and MEMRI to understand deep brain processing of complex stimulus. After completing his doctoral degree, Benoit started his postdoc at Roche Ltd (Basel Switzerland) in collaboration with the Wyss-Coray lab at Stanford University. He studied normal and abnormal aging to identify biomarkers that could be used for the early detection of diseases and/or targeted to develop new treatments.
Benoit Lehallier
Instructor
lehallib[at]stanford.edu
Having a strong interest in aging, neurodegeneration, and learning and memory, I joined the Wyss-Coray lab in hopes of using novel experimental approaches to uncover mechanistic aspects of how the systemic environment influences the aging brain. I was able to develop a system to label proteins specifically in the liver using bioorthogonal labeling, then detect these labeled proteins in plasma, as well as in the brain after these proteins cross the blood-brain barrier. I am now labeling proteins in the brain to determine what proteins secreted by neurons can be found in the bloodstream. This work may lead to a pool of protein targets that can be used as blood biomarkers for neurodegenrative diseases.
Kyle Brewer
Postdoctoral Fellow
kdbrewer[at]stanford.edu
I received my graduate degree in Integrative Biology of Disease from the University of Southern California in 2015. For my thesis, I studied the role of T cells in pediatric brain cancer and also explored the role of microglial TLR receptor signaling in Alzheimer’s disease. For this work, I received an NIH/NINDS F31 fellowship. I joined the Wyss-Coray lab in 2015 to explore the role adaptive immunity in Alzheimer’s disease in collaboration with the Stanford Alzheimer’s Disease Research Center. I am a recipient of a Glenn/AFAR Postdoctoral Fellowship in the Biology of Aging, an NIH/NIA F32, Alzheimer’s Association Young Investigator Award and a Junior Faculty Award from the AD/PD Congress. Outside of the lab, I enjoy hiking, camping and playing basketball.
David Gate
Postdoctoral Fellow
dgate[at]stanford.edu
Oliver Hahn
Postdoctoral Fellow
olihahn[at]stanford.edu
Michael Haney
Postdoctoral Fellow
haney[at]stanford.edu
Tal Iram
Postdoctoral Fellow
tal.iram[at]stanford.edu
“Prior to joining the Wyss-Coray lab, I completed my PhD degree in Neuroscience at the University of Miami. For my thesis project, I worked on a prophylactic approach to cerebral ischemia known as preconditioning by focusing on the metabolic adaptations it induces in the brain. For my postdoctoral project, I am interested in understanding how alterations in the cerebrovasculature observed during aging and neurodegeneration contribute to disease pathology.
Nathalie Khoury
Postdoctoral Fellow
nkhoury[at]stanford.edu
Song Eun Lee
Postdoctoral Fellow
songlee[at]stanford.edu
Tristan Qingyun Li
Postdoctoral Fellow
ql20[at]stanford.edu
During my Ph.D. at the University of Salzburg, Austria, I studied muscle stem cells in adult zebrafish. For my post doc, having always been intrigued by the brain, I changed my research focus to neural stem cells and joined the Aigner lab (PMU Salzburg). Here I became interested in the identification of mechanisms that contribute to reduced neurogenesis and to neuroinflammation in aging. I could identify leukotrienes as key mediators for brain aging and showed that its pharmacological inhibition ameliorated neuroinflammation and improved cognition in aged rats. I joined the Wyss-Coray lab in August 2015 to further explore the role of microglia in brain aging. Specifically, I aim to understand the role of microglial lipid accumulations in structural and functional brain aging. Also, I started to work on the killifish as a new model to study microglia and brain aging.
Julia Marschallinger
Senior Scientist
jumars[at]stanford.edu
Zurine Miguel
Senior Scientist
zurine[at]stanford.edu
Patricia Moran Losada
Postdoctoral Fellow
pmlosada[at]stanford.edu
Robert Palovics
Postdoctoral Fellow
palovics[at]stanford.edu
My goal is to keep people as healthy as possible for as long as possible. To accomplish this, I study the biology of aging, as aging is the root cause of the majority of deaths and disease worldwide. I hope to develop therapies to treat these root causes and prevent diseases like cancer, heart disease, Alzheimer's, stroke, and diabetes. My main areas of focus have been cellular senescence, how young circulating factors rejuvenate aged tissues, and characterizing organism-wide aging with RNA-seq and scRNA-seq.
Nick Schaum
Postdoctoral Fellow
nschaum[at]stanford.edu
Liana Bonnano
MD PhD Student
lianab[at]stanford.edu
I am an MD-PhD student in the MSTP program. Prior to joining the Wyss-Coray lab, I worked in Irv Weissman’s lab investigating the pathogenesis of and immunotherapies for myelodysplastic syndrome. I am interested in the role of microglia and peripheral myeloid cells in aging.
John Pluvinage
MD PhD Student
johnpl1[at]stanford.edu
Ryan grew up in Lexington, NC and earned his BS in Chemical Engineering at North Carolina State University. He is currently PhD candidate in the Stanford department of Chemical Engineering and is coadvised by James Swartz. His research focuses on developing therapeutics to target age and disease-associated neuroinflammation.
Ryan Vest
Graduate Student
rtvest[at]stanford.edu
Steven earned his BS in Chemistry at UC Berkeley under Richmond Sarpong doing research in synthetic organic chemistry. Steven then came to Stanford, earning an MS in Chemistry in the Burns lab studying the synthesis and biophysics of structurally unusual lipids. Finally, he joined the Wyss-Coray lab as a BioX SIGF Fellow to complete a PhD in Chemistry. He studies changes in the cerebrospinal fluid proteome that occur with aging, rejuvenation, and Alzheimer’s disease using state-of-the-art mass spectrometry techniques.
Steven Shuken
Graduate Student
shuken[at]stanford.edu
Andrew is a bioengineering PhD student developing chemical and genetic tools to study blood-brain barrier function with age.
Andrew Yang
Graduate Student
andcyang[at]stanford.edu
Davis Lee
Research Associate
dpklee.nyda[at]gmail.com
Olivia graduated from Swarthmore college in 2018 with a degree in honors neuroscience. In the Wyss-Coray lab, she is working to understand the role of the adaptive immune system in Alzheimer’s disease. Olivia hopes to pursue a dual MD/MPH degree in order to expand her career in research to understanding and reducing global health disparities.
Olivia Leventhal
Research Associate
olivialeventhal[at]stanford.edu
Christy Munson
Research Associate
cmunson2[at]stanford.edu
Achint Kaur
Research Associate
akaur21[at]stanford.edu
Ailene Chan
Undergraduate Student
aileneyc[at]stanford.edu
Winnie Chen
Undergraduate Student
wchen2[at]stanford.edu
Saket Myneni
Undergraduate Student
skmyneni[at]stanford.edu
Originally from Singapore, I am a sophomore at Stanford University majoring in Chemical Engineering and Biology. I started college with an interest in neurodegenerative disease, but that grew to include the general biology of brain aging. I am particularly interested in changes in microglia and cerebrospinal fluid with age and disease.
Jerry Sun
Undergraduate Student
jrsun[at]stanford.edu
Kathleen Dickey
Research Data Analyst
kdickey[at]stanford.edu
Name
Lab Member
Lab Position
Current Position
2018-2019
Postdoctoral Fellow
2012-2018
Postdoctoral Fellow
2007-2015
Graduate Student
Postdoctoral Fellow, California Institute for Quantitative Biosciences, UC Berkeley, Berkeley, CA
2008-2015
Postdoctoral Fellow
2008-2015
Graduate Student
Postdoctoral Fellow, UCSF, Yuh Nung Jan Lab
2011-2015
Postdoctoral Fellow
Scientist, Utrecht University, The Netherlands
2008-2014
Postdoctoral Fellow
Scientist, Janssen R&D LLC., San Diego
2009-2014
Graduate Student
Assistant Professor of Natural Sciences, Minerva Schools at KGI
2013-2014
Postdoctoral Fellow
Postdoctoral Fellow, University of Texas Southwestern Medical Center, Dallas, Texas
2007-2013
Postdoctoral Fellow
Assistant Professor, Eastern Connecticut State University, CT
Jeong Soo Park
2009-2012
Postdoctoral Fellow
Assistant Professor, Department of Biochemistry, College of Medicine, Dankook Cheonan, South Korea
2007-2012
Graduate Student
Scientist, Janssen Pharmaceutical Companies of Johnson & Johnson
2006-2011
Graduate Student
Biochemist,Assay Developer,Big Data Analyst at Phenvogen, San Diego, CA
2007-2010
Postdoctoral Fellow
Associate Professor, Dep. of Therapeutic Development for Intractable Neurological Disease, Juntendo University
2003-2009
Postdoctoral Fellow
Principal Scientist, F. Hoffman-LaRoche Ltd.,Basel, Switzerland
2006-2008
Postdoctoral Fellow
Assistant Professor, Department of Anesthesiology, Kagoshima University, Japan
2001-2007
Postdoctoral Fellow
Senior Scientist, Janssen Pharmaceutical Companies, Johnson & Johnson, Belgium
2004-2007
Postdoctoral Fellow
Senior Investigator/Head of Neurodegeneration, Novartis, Inc., Cambridge, MA
Amy Lin
2002-2004
Postdoctoral Fellow
Scientist, Sidney Kimmel Cancer Center, San Diego, CA
2003
Postdoctoral Fellow
Assistant Professor of Neuroscience, Iwate Medical University, Iwate, Japan